Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SMUGS5_RS08590 Genome accession   NC_018089
Coordinates   1776456..1777781 (-) Length   441 a.a.
NCBI ID   WP_014835041.1    Uniprot ID   -
Organism   Streptococcus mutans GS-5     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1771456..1782781
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SMUGS5_RS10230 (SMUGS5_08515) - 1771856..1772020 (-) 165 WP_002265308.1 hypothetical protein -
  SMUGS5_RS10690 - 1772460..1772672 (+) 213 Protein_1664 IS3 family transposase -
  SMUGS5_RS08570 (SMUGS5_08525) - 1772795..1773199 (-) 405 WP_002274065.1 hypothetical protein -
  SMUGS5_RS08575 (SMUGS5_08530) - 1773346..1773765 (-) 420 WP_002263913.1 hypothetical protein -
  SMUGS5_RS08580 (SMUGS5_08535) - 1775146..1775547 (-) 402 WP_002310604.1 hypothetical protein -
  SMUGS5_RS10505 - 1775678..1775907 (-) 230 Protein_1668 Blp family class II bacteriocin -
  SMUGS5_RS08585 (SMUGS5_08550) comC/blpC 1776174..1776314 (+) 141 WP_002267610.1 ComC/BlpC family leader-containing pheromone/bacteriocin Regulator
  SMUGS5_RS08590 (SMUGS5_08555) comD/blpH 1776456..1777781 (-) 1326 WP_014835041.1 sensor histidine kinase Regulator
  SMUGS5_RS08595 (SMUGS5_08560) comE/blpR 1777778..1778530 (-) 753 WP_002270252.1 response regulator transcription factor Regulator
  SMUGS5_RS08600 (SMUGS5_08565) - 1779001..1779639 (-) 639 WP_002271525.1 VTT domain-containing protein -
  SMUGS5_RS08605 (SMUGS5_08570) - 1779687..1780313 (-) 627 WP_002265453.1 hypothetical protein -
  SMUGS5_RS08610 (SMUGS5_08575) der 1780388..1781698 (-) 1311 WP_002280559.1 ribosome biogenesis GTPase Der -
  SMUGS5_RS08615 (SMUGS5_08580) dnaI 1781711..1782610 (-) 900 WP_002267936.1 primosomal protein DnaI -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 50598.73 Da        Isoelectric Point: 9.7605

>NTDB_id=52053 SMUGS5_RS08590 WP_014835041.1 1776456..1777781(-) (comD/blpH) [Streptococcus mutans GS-5]
MNEALMILSNGLLTYLTVLFLLFLFSKVSNVTLSKKELTLFSISNFLIMIAVTMVNVNLFYPAEPLYFIVLSIYLNRQNS
LSLNIFYGLLPVASSDLFRRAIIFFILDGNQGIVMDSSIITTYMIEFAGIALSYLFLSVFNVDIGRLKDSLTKMKVKKRL
IPMNITMLLYYLLIQALYIIESYNVIPTLKFRKFVVIVYLILFLILISFLSQYTKQKVQNEIMAQKEAQIRNITQYSQQI
ESLYKDIRSFRHDYLNILTSLRLGIENKDLASIEKIYHQILEKTGHQLQDTRYNIGHLANIQNDAVKGILSAKILEAQNK
KIAVNVEVSSKIQLPEMELLDFITILSILCDNAIEAAFESLNPEIQLAFFKKNGSIVFIIQNSTKEKQIDVSKIFKENYS
TKGSNRGIGLAKVNHILEHYPKTSLQTSSHHHLFKQLLIIK

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=52053 SMUGS5_RS08590 WP_014835041.1 1776456..1777781(-) (comD/blpH) [Streptococcus mutans GS-5]
ATGAATGAAGCCTTAATGATACTTTCAAATGGTTTATTAACTTATCTAACCGTTCTATTTCTCTTGTTTCTATTTTCTAA
GGTAAGTAATGTCACTTTATCGAAAAAGGAATTAACCCTTTTTTCGATAAGCAATTTTCTGATAATGATTGCTGTTACGA
TGGTAAATGTAAACCTGTTTTATCCTGCAGAGCCTCTTTATTTTATAGTTTTATCAATTTATCTTAATAGACAGAATAGT
CTTTCTCTAAATATATTTTATGGTCTGCTGCCTGTTGCCAGTTCTGACTTGTTTAGGCGGGCAATCATATTCTTTATCTT
GGATGGAAATCAAGGAATTGTAATGGACAGTAGCATTATAACCACCTATATGATCGAGTTTGCAGGAATAGCGCTAAGTT
ACCTCTTTCTAAGTGTGTTCAATGTTGATATTGGTCGACTTAAAGATAGTTTGACCAAGATGAAGGTCAAAAAACGCTTG
ATCCCAATGAATATTACTATGCTTCTATACTACCTTTTAATACAGGCATTGTATATTATAGAGAGTTATAATGTGATACC
GACTTTAAAATTTCGTAAATTTGTCGTTATTGTCTATCTTATTTTATTTTTGATTCTGATCTCATTTTTAAGCCAATATA
CCAAACAAAAGGTTCAAAATGAGATAATGGCACAAAAGGAAGCTCAGATTCGAAATATCACCCAGTATAGTCAGCAAATA
GAATCTCTTTACAAGGATATTCGAAGTTTCCGCCATGATTATCTGAATATTTTAACTAGCCTCAGATTAGGCATTGAAAA
TAAAGATTTAGCTAGTATTGAAAAGATTTACCATCAAATCTTAGAAAAAACAGGACATCAATTGCAGGATACCCGTTATA
ATATCGGCCATCTAGCTAATATTCAAAACGATGCTGTCAAGGGTATCTTGTCAGCAAAAATCTTAGAAGCTCAGAATAAA
AAGATTGCTGTCAATGTAGAAGTCTCAAGTAAAATACAACTGCCTGAGATGGAGTTGCTTGATTTCATTACCATACTTTC
TATCTTGTGTGATAATGCCATTGAGGCTGCTTTCGAATCATTAAATCCTGAAATTCAGTTAGCCTTTTTTAAGAAAAATG
GCAGTATAGTCTTTATCATTCAGAATTCCACCAAAGAAAAACAAATAGATGTGAGTAAAATTTTTAAAGAAAACTATTCC
ACTAAAGGCTCCAATCGCGGTATTGGTTTAGCAAAGGTGAATCATATTCTTGAACATTATCCCAAAACCAGTTTACAAAC
AAGCAGTCATCATCATTTATTCAAGCAACTCCTAATAATAAAATAG

Domains

Predicted by InterproScan.

GHKL domain (HATPase_c_5)

(337-440)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

98.639

100

0.986

Multiple sequence alignment