Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   ICN77_RS04725 Genome accession   NZ_CP066376
Coordinates   869679..870395 (-) Length   238 a.a.
NCBI ID   WP_001829999.1    Uniprot ID   C0LF82
Organism   Staphylococcus epidermidis strain PH1-28     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 864679..875395
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ICN77_RS04710 (ICN77_000797) - 865960..866913 (+) 954 WP_002503805.1 LacI family DNA-binding transcriptional regulator -
  ICN77_RS04715 (ICN77_000798) - 867173..868645 (+) 1473 WP_198895860.1 sucrose-6-phosphate hydrolase -
  ICN77_RS04720 (ICN77_000799) - 868652..869611 (+) 960 WP_002485130.1 carbohydrate kinase -
  ICN77_RS04725 (ICN77_000800) agrA 869679..870395 (-) 717 WP_001829999.1 LytTR family DNA-binding domain-containing protein Regulator
  ICN77_RS04730 (ICN77_000801) - 870412..871701 (-) 1290 WP_002457064.1 GHKL domain-containing protein -
  ICN77_RS04735 (ICN77_000802) - 871726..871866 (-) 141 WP_002447513.1 cyclic lactone autoinducer peptide -
  ICN77_RS04740 (ICN77_000803) - 871872..872435 (-) 564 WP_002457915.1 accessory gene regulator AgrB -
  ICN77_RS04745 (ICN77_000804) hld 872752..872829 (+) 78 WP_002494082.1 delta-hemolysin -
  ICN77_RS04750 (ICN77_000805) - 873210..873995 (-) 786 WP_198895861.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27936.97 Da        Isoelectric Point: 5.6250

>NTDB_id=519528 ICN77_RS04725 WP_001829999.1 869679..870395(-) (agrA) [Staphylococcus epidermidis strain PH1-28]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELALATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=519528 ICN77_RS04725 WP_001829999.1 869679..870395(-) (agrA) [Staphylococcus epidermidis strain PH1-28]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAGCTTTAGCAACAAATGATCCTTATGAGGTCTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAGCTGACTTATTTGACGTTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAAGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTCGAAACAGCACATACACGACTCAAATTAT
TATCAAAAGAAAGTAATGTAGATACGATTGAGTTAAAGCGGGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGGCTCATTGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTGATAAACAGGCATAATATTGAATCTATTG
ACTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C0LF82

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.815

100

0.878
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374