Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   JDY60_RS08290 Genome accession   NZ_CP066172
Coordinates   1723596..1724894 (+) Length   432 a.a.
NCBI ID   WP_200370622.1    Uniprot ID   -
Organism   Streptococcus oralis strain SF100     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1718596..1729894
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JDY60_RS08265 (JDY60_08265) rpsB 1719421..1720200 (+) 780 WP_000268475.1 30S ribosomal protein S2 -
  JDY60_RS08270 (JDY60_08270) tsf 1720279..1721319 (+) 1041 WP_000808056.1 translation elongation factor Ts -
  JDY60_RS08275 (JDY60_08275) cysK 1721423..1722349 (-) 927 WP_000158480.1 cysteine synthase A -
  JDY60_RS08280 (JDY60_08280) - 1722446..1722889 (-) 444 WP_200370619.1 PH domain-containing protein -
  JDY60_RS08285 (JDY60_08285) - 1722904..1723539 (-) 636 WP_200370621.1 YigZ family protein -
  JDY60_RS08290 (JDY60_08290) comFA/cflA 1723596..1724894 (+) 1299 WP_200370622.1 DEAD/DEAH box helicase Machinery gene
  JDY60_RS08295 (JDY60_08295) comFC/cflB 1724891..1725553 (+) 663 WP_200370624.1 ComF family protein Machinery gene
  JDY60_RS08300 (JDY60_08300) hpf 1725633..1726181 (+) 549 WP_000599114.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  JDY60_RS08305 (JDY60_08305) - 1726263..1727441 (+) 1179 WP_200370626.1 acetyl-CoA C-acetyltransferase -
  JDY60_RS08310 (JDY60_08310) - 1727598..1729571 (+) 1974 WP_000739978.1 DHH family phosphoesterase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49705.58 Da        Isoelectric Point: 8.0229

>NTDB_id=518087 JDY60_RS08290 WP_200370622.1 1723596..1724894(+) (comFA/cflA) [Streptococcus oralis strain SF100]
MKVNPNYLGRLFTEKELTEEERQEAVRLPAMRKEKGKLFCQRCNSLILEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDILKWRGQLTPFQEKVSEGLLQAIDKQEPTLVHAVTGAGKTEMIYQVVAKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVVATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRMFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LKEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKNMNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=518087 JDY60_RS08290 WP_200370622.1 1723596..1724894(+) (comFA/cflA) [Streptococcus oralis strain SF100]
ATGAAAGTAAATCCAAATTATCTCGGTCGCTTGTTTACTGAGAAAGAATTAACGGAAGAAGAACGACAGGAAGCAGTGAG
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAATAGTTTGATTCTAGAAGAATGGTATTTGC
CTATCGGCGCTTACTATTGTAGGGAGTGTTTACTGATGAAGAGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCTCAA
GAGGATTTTCCTAAGCAAGACATCCTCAAATGGCGTGGTCAGTTAACACCTTTTCAAGAAAAAGTGTCAGAGGGACTGCT
TCAAGCAATAGACAAGCAAGAGCCAACCTTGGTTCACGCTGTGACAGGAGCTGGAAAGACAGAGATGATTTATCAAGTTG
TGGCTAAAGTGATTGATGATGGTGGTGCAGTTTGTTTGGCCAGTCCTCGAATTGATGTGTGTTTAGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAGTTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATGTTCCTTACGGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATC
TTGAAGGAGCAGTACCCGAATGAGAATATCGGCTTTGTGTCTTCTGTGACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGCGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGTTTGATTCAGATTGGAGGGCGAGTTGGACGCAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTCTTTCATGATGGATTAAATGCTTCCATCAAAAAGGCAATCAAGGAAATCAAGAATATGAA
TAAGGAGGCAGGGTTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-396)

Type III restriction enzyme, res subunit (ResIII)

(94-166)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

90.741

100

0.907
  comFA/cflA Streptococcus pneumoniae Rx1

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae D39

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae R6

90.509

100

0.905
  comFA/cflA Streptococcus pneumoniae TIGR4

90.278

100

0.903
  comFA/cflA Streptococcus mitis SK321

90.046

100

0.9
  comFA Lactococcus lactis subsp. cremoris KW2

51.345

94.676

0.486
  comFA Latilactobacillus sakei subsp. sakei 23K

39.08

100

0.394