Detailed information NTG0518068

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JDY60_RS06985
• Genome accession: NZ_CP066172
• Coordinates: 1476746..1477756 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis strain SF100
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1471746..1482756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JDY60_RS06970 (JDY60_06970)	-	1471799..1473775 (-)	1977	WP_200370509.1	CAP domain-containing protein	-
JDY60_RS06975 (JDY60_06975)	-	1474274..1475665 (-)	1392	WP_084856762.1	Cof-type HAD-IIB family hydrolase	-
JDY60_RS06980 (JDY60_06980)	-	1475731..1476693 (+)	963	WP_061426607.1	asparaginase	-
JDY60_RS06985 (JDY60_06985)	ccpA	1476746..1477756 (-)	1011	WP_001090635.1	catabolite control protein A	Regulator
JDY60_RS06990 (JDY60_06990)	-	1477961..1478278 (+)	318	WP_000886045.1	DUF960 domain-containing protein	-
JDY60_RS06995 (JDY60_06995)	-	1478329..1479612 (-)	1284	WP_001125354.1	membrane protein	-
JDY60_RS07000 (JDY60_07000)	folK	1479605..1480426 (-)	822	WP_000372502.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
JDY60_RS07005 (JDY60_07005)	folE	1480585..1481139 (-)	555	WP_200370510.1	GTP cyclohydrolase I FolE	-
JDY60_RS07010 (JDY60_07010)	-	1481143..1482444 (-)	1302	WP_200370511.1	folylpolyglutamate synthase/dihydrofolate synthase family protein	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=518068 JDY60_RS06985 WP_001090635.1 1476746..1477756(-) (ccpA) [Streptococcus oralis strain SF100]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=518068 JDY60_RS06985 WP_001090635.1 1476746..1477756(-) (ccpA) [Streptococcus oralis strain SF100]
ATGAACACAGATGATACAGTAACGATTTATGACGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCAAACATTACCAATGGTTATTTCTCA
ACACTTGCTAAGGGGATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTTGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTTTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTAGATGTAGAACACCAACTTCCAAGT
GTAAATATCGACTACAAACAAGCAACGATTGATGCTGTAAGCTACCTTCTCAAAGAAAACGAAAAGATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTACAAGGAAGCCTTGAAAAAAGCTGGACATTCTT
ATAGTGAGGGATTGGTCTTTGAATCAAAATACAGCTATGACGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCAGCAGGTGTGTTGAATGGTTTAGCTGACCATGGTGTATCTGTGCC
GGAAGAGTTTGAAATCATCACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACGACTATTGCCCAAC
CTCTTTATGACTTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTACCTCATGGTTTGACAGAGCGCCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568