Detailed information NTG0517596

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: JC624_RS18160
• Genome accession: NZ_CP066124
• Coordinates: 3778559..3779971 (+)
• Length: 470 a.a.
• NCBI ID: WP_005065713.1
• Uniprot ID: A0A009RVI8
• Organism: Acinetobacter pittii strain 32292
• Function: regulation of type IV pilus assembly (predicted from homology) Competence regulation

Genomic Context

Location: 3773559..3784971

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JC624_RS18140	thrC	3773817..3774956 (+)	1140	WP_002048893.1	threonine synthase	-
JC624_RS18145	pbpG	3775062..3776108 (-)	1047	WP_005804058.1	D-alanyl-D-alanine endopeptidase PBP7/8	-
JC624_RS18150	gacA	3776321..3776956 (+)	636	WP_002121174.1	response regulator	-
JC624_RS18155	pilS	3776967..3778535 (+)	1569	WP_227062294.1	sensor histidine kinase	Regulator
JC624_RS18160	pilR	3778559..3779971 (+)	1413	WP_005065713.1	sigma-54-dependent transcriptional regulator	Regulator
JC624_RS18165	ctpA	3779975..3781159 (-)	1185	WP_227062296.1	S41 family peptidase	-
JC624_RS18170	gpmI	3781175..3782722 (-)	1548	WP_005065710.1	2,3-bisphosphoglycerate-independent phosphoglycerate mutase	-
JC624_RS18175	lptG	3782849..3783919 (-)	1071	WP_002121203.1	LPS export ABC transporter permease LptG	-

Sequence

Protein

• Length: 470 a.a.
• Molecular weight: 52610.64 Da
• Isoelectric Point: 6.3452

>NTDB_id=517596 JC624_RS18160 WP_005065713.1 3778559..3779971(+) (pilR) [Acinetobacter pittii strain 32292]
MAEQQPLVLLVDDEEDLCLLMQMTLARMGIKTHLAYRVEQAKQLFTQFHYDACLTDLNLPDGSGLELVQHVSQTYPHTPI
AVLTAYGNMDIAIAALKAGAFDFVSKPINQIHLDQLLKKALNQPKPEHEFGETTLENDLLIGRSPPIQNLRTAIKKIARS
QAPVFVTGESGTGKEVVANLIHRLSNRSEGPFIAINCGAIPTELMESELFGHKKGSFTGATQDKQGLILSAHGGSLFLDE
IAELPLSMQVKLLRAVQEKKIRPVGSDQEIDVDFRVISASHQDLDLLVQQGKFRQDLFFRIHVMDIMLPPLRDRGGDILL
LANHFIQKVCTEWGISSKQLTASAETYLLQQDFPGNVRELRNMIERAITLSDDESIDLTHLAPPLRGSSVSPQIVTKQLN
QTPAVQTHPKFPMEGLERYLENIEKDILLNALNMTHWNRTLAAKKLGMTFRSLRYRLKKFGLDTEMGEEV

Nucleotide

• Length: 1413 bp

>NTDB_id=517596 JC624_RS18160 WP_005065713.1 3778559..3779971(+) (pilR) [Acinetobacter pittii strain 32292]
ATGGCAGAACAGCAACCACTCGTTTTGCTTGTAGACGATGAAGAAGATTTGTGCCTGTTAATGCAAATGACTCTTGCACG
AATGGGGATTAAGACACATCTTGCTTATCGGGTTGAACAGGCCAAACAGCTTTTTACTCAGTTTCATTACGATGCGTGCT
TGACCGATTTAAACCTACCCGACGGTAGTGGTTTAGAATTGGTCCAACATGTTTCTCAAACTTACCCACACACACCCATT
GCAGTCTTAACTGCATACGGCAATATGGATATTGCAATTGCAGCATTAAAAGCGGGAGCTTTTGATTTTGTCAGCAAACC
TATTAACCAAATTCATTTAGATCAGTTGTTAAAAAAGGCGCTCAACCAGCCAAAACCAGAGCATGAATTTGGTGAAACAA
CTCTAGAGAATGACTTATTAATTGGGCGTTCACCACCTATACAAAACTTACGGACAGCTATTAAAAAAATAGCCCGCTCC
CAAGCTCCTGTATTTGTTACAGGCGAGTCTGGTACGGGTAAAGAAGTTGTTGCGAATCTGATTCACCGCTTAAGCAACCG
CAGTGAAGGACCATTTATTGCAATTAACTGTGGAGCAATCCCAACAGAGCTCATGGAAAGTGAACTTTTCGGGCATAAAA
AAGGGAGCTTTACTGGAGCGACTCAAGATAAACAAGGTCTTATTTTATCGGCACACGGCGGCAGTTTATTTTTAGATGAA
ATTGCTGAATTGCCTTTAAGTATGCAGGTTAAATTGCTTCGGGCAGTACAAGAGAAAAAGATTCGCCCTGTCGGTTCAGA
TCAGGAAATTGATGTTGATTTTCGAGTAATTAGTGCCAGTCACCAAGATTTAGATTTGTTAGTCCAACAAGGTAAATTCC
GTCAGGACTTATTTTTCCGCATTCATGTTATGGATATTATGTTACCACCACTGCGTGACCGTGGTGGAGATATTTTGCTA
TTGGCCAATCATTTTATTCAAAAGGTTTGTACGGAATGGGGAATTTCAAGCAAGCAATTAACAGCGAGCGCTGAAACTTA
CTTATTGCAGCAAGACTTTCCGGGTAATGTTCGTGAATTAAGAAATATGATTGAACGAGCTATTACTTTAAGTGATGATG
AGTCCATTGATTTAACACACTTAGCGCCTCCTCTTAGAGGCAGTAGCGTAAGCCCGCAAATCGTAACGAAACAACTAAAT
CAAACACCGGCTGTTCAGACTCACCCAAAATTTCCAATGGAAGGTTTAGAACGTTACTTAGAAAATATCGAAAAAGATAT
TTTACTGAATGCTCTGAACATGACACATTGGAATCGAACTTTGGCCGCTAAAAAGCTAGGAATGACATTCCGTTCTTTAC
GCTATCGACTCAAAAAATTTGGCTTAGATACCGAAATGGGAGAGGAAGTATAA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (8-116)

• Bacterial regulatory protein, Fis family (HTH_8) (420-460)

• Sigma-54 interaction domain (Sigma54_activat) (140-306)

3D structure

• AlphaFold DB: A0A009RVI8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Acinetobacter baumannii strain A118	86.047	100	0.866
pilR	Pseudomonas aeruginosa PAK	51.096	97.021	0.496