Detailed information    

insolico Bioinformatically predicted

Overview

Name   amiA   Type   Regulator
Locus tag   I6H78_RS08515 Genome accession   NZ_CP066059
Coordinates   1733147..1735105 (+) Length   652 a.a.
NCBI ID   WP_198459406.1    Uniprot ID   A0A7T4M0D2
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   internalize XIP (predicted from homology)   
Competence regulation

Genomic Context

Location: 1728147..1740105
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS08490 (I6H78_08490) - 1728291..1728803 (+) 513 WP_198459402.1 YiiX/YebB-like N1pC/P60 family cysteine hydrolase -
  I6H78_RS08495 (I6H78_08495) - 1728787..1729437 (+) 651 WP_198459403.1 DUF1803 domain-containing protein -
  I6H78_RS08500 (I6H78_08500) - 1729539..1729739 (+) 201 WP_000051179.1 CsbD family protein -
  I6H78_RS08505 (I6H78_08505) - 1729771..1731216 (-) 1446 WP_198459404.1 UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L- lysine ligase -
  I6H78_RS08510 (I6H78_08510) - 1731322..1732944 (+) 1623 WP_198459405.1 polysaccharide biosynthesis protein -
  I6H78_RS08515 (I6H78_08515) amiA 1733147..1735105 (+) 1959 WP_198459406.1 peptide ABC transporter substrate-binding protein Regulator
  I6H78_RS08520 (I6H78_08520) - 1735251..1736345 (+) 1095 WP_198459407.1 cystathionine gamma-synthase -
  I6H78_RS08525 (I6H78_08525) - 1736353..1737519 (+) 1167 WP_198459408.1 MalY/PatB family protein -

Sequence

Protein


Download         Length: 652 a.a.        Molecular weight: 72877.02 Da        Isoelectric Point: 4.6991

>NTDB_id=516995 I6H78_RS08515 WP_198459406.1 1733147..1735105(+) (amiA) [Streptococcus oralis strain FDAARGOS_1021]
MKKSKAKYLTLASVVLSAGILLSACGNSSSATKTYNYVYSNDPSSLNYLAENRATTNDIVTNLVDGLMENDQYGNYVPSL
AEDWTVSQDGLTYTYKLRKDAKWYTYEGEEYAPVTAQDFVTGLKYAADKKSEALYLVQDSVAGLDDYINGKTTDFSTVGV
KAIDDQTVQYTLTRPEPYWNSKTTSTILFPVNADFLKSKGDDFGKVDPSSILYSGPFLMKSFVSKSVIEYKKNPNYWDAK
NVFVDDVKLTYYDGSDQDALARNFVEGVYSYALLYPNSSSFEGIKEKNKDNIIYSMQNATSYYLNFNLDRKSYNFTSKSS
DIEKKSTQEAVLNKNFRQAFNYAYNRTAYGAQSQGEEGATKIIRNLVVPPTFVSINGKDFGDVVSEKMVNYGQEWQGINF
ADAQDPYYNPDKAKAKFAEAKKELEAKGVQFPIHLDVTVDQSAKKGVLEASSLKQSIESVLGAENVVIDIQQLSTDDFDN
SSYLAQTAAQKDFDIYNGGWSADYLDPSSYLDILNVNNGGMLQNIGLEPGEVNDKAKAVGLDTYTQMLEEANKEQEPAKR
YEKYAEIQAWLVDSALAIPNVSQGGTPTLRKTVPFSSPFSQAGNKGVESYKYLKLQDKTVTADEYEKAKEKWQKEKEESN
KKAQEELAKHVK

Nucleotide


Download         Length: 1959 bp        

>NTDB_id=516995 I6H78_RS08515 WP_198459406.1 1733147..1735105(+) (amiA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAAAGTCTAAGGCCAAGTATCTGACACTTGCAAGTGTCGTGTTAAGCGCAGGTATCTTACTGAGCGCATGTGGAAA
TTCAAGTAGCGCTACTAAAACATATAACTATGTTTATTCGAACGATCCATCTAGTTTGAACTATCTTGCAGAAAACCGTG
CAACAACCAATGACATCGTGACCAATTTGGTGGATGGGTTGATGGAAAATGACCAATACGGTAACTATGTTCCATCATTG
GCAGAGGATTGGACTGTTTCTCAGGACGGTTTGACCTATACTTACAAATTGCGTAAGGATGCAAAATGGTATACTTATGA
GGGTGAAGAATACGCCCCTGTAACGGCCCAAGACTTTGTGACAGGTTTGAAATATGCTGCTGATAAAAAATCCGAAGCCT
TGTACCTGGTTCAAGACTCTGTAGCAGGTTTGGATGACTATATCAACGGGAAAACAACTGACTTTTCAACAGTCGGTGTT
AAGGCTATTGATGACCAAACAGTTCAGTACACTTTGACACGTCCAGAACCTTATTGGAATTCTAAAACAACTTCAACCAT
TCTCTTCCCTGTCAATGCAGACTTCTTGAAATCAAAAGGGGATGATTTTGGTAAGGTAGATCCTTCTAGCATTTTGTACA
GTGGACCTTTCTTGATGAAATCGTTTGTTTCAAAATCTGTTATCGAATACAAGAAAAATCCAAATTACTGGGATGCTAAA
AATGTCTTTGTGGACGATGTGAAATTGACTTACTATGACGGTAGTGACCAGGATGCCCTAGCTCGTAACTTCGTAGAAGG
AGTATACAGCTACGCACTTCTCTACCCAAATAGCTCAAGCTTTGAAGGCATTAAAGAGAAGAACAAGGATAACATCATCT
ATAGTATGCAAAACGCAACTTCTTATTACTTGAACTTCAACTTAGACAGAAAATCTTATAACTTCACTTCTAAATCCTCA
GATATCGAAAAGAAATCAACCCAAGAAGCAGTTCTGAATAAAAACTTCCGTCAAGCCTTCAACTATGCTTATAACCGTAC
AGCCTATGGAGCACAATCTCAAGGGGAAGAAGGAGCAACAAAGATTATTCGTAACTTGGTTGTACCTCCTACGTTTGTAA
GTATCAACGGAAAAGACTTTGGCGATGTTGTTTCAGAAAAGATGGTCAACTATGGCCAAGAATGGCAAGGAATCAACTTT
GCAGATGCACAAGATCCATACTACAATCCTGATAAAGCTAAAGCTAAATTTGCAGAAGCTAAGAAAGAATTGGAAGCTAA
GGGTGTGCAATTCCCAATCCACTTGGATGTAACAGTTGACCAATCAGCTAAAAAAGGTGTACTTGAAGCAAGTTCTTTGA
AACAATCCATCGAATCTGTTCTAGGAGCTGAGAATGTGGTTATCGATATCCAACAGCTATCAACAGATGACTTTGACAAC
TCTAGCTACCTCGCTCAAACCGCAGCTCAAAAAGACTTTGATATCTATAATGGCGGTTGGAGTGCTGACTACTTGGATCC
ATCAAGCTATCTTGATATCTTAAATGTCAATAACGGTGGTATGTTGCAAAACATTGGTCTAGAACCAGGTGAGGTCAATG
ACAAGGCTAAGGCAGTTGGTCTGGATACTTACACTCAAATGTTAGAAGAAGCGAACAAGGAGCAAGAACCAGCGAAACGT
TATGAAAAATATGCGGAAATTCAAGCTTGGCTCGTTGATAGCGCCCTTGCTATTCCAAACGTTTCTCAGGGTGGAACACC
GACCTTGAGAAAGACAGTTCCATTCTCATCACCATTCTCACAAGCTGGAAATAAGGGTGTCGAATCATACAAGTATCTCA
AGTTGCAAGATAAGACTGTAACGGCTGATGAGTATGAAAAAGCTAAAGAAAAATGGCAGAAAGAAAAAGAAGAATCAAAT
AAAAAAGCCCAAGAAGAACTGGCAAAACATGTTAAATAA

Domains

Predicted by InterproScan.

Bacterial extracellular solute-binding proteins, family 5 Middle (SBP_bac_5)

(76-519)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T4M0D2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  amiA Streptococcus salivarius strain HSISS4

55.775

100

0.563
  amiA3 Streptococcus thermophilus LMG 18311

55.235

100

0.558
  amiA3 Streptococcus thermophilus LMD-9

54.932

100

0.555