Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   I6H78_RS05530 Genome accession   NZ_CP066059
Coordinates   1135651..1136949 (+) Length   432 a.a.
NCBI ID   WP_198459046.1    Uniprot ID   -
Organism   Streptococcus oralis strain FDAARGOS_1021     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1130651..1141949
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I6H78_RS05505 (I6H78_05505) rpsB 1131476..1132255 (+) 780 WP_000268477.1 30S ribosomal protein S2 -
  I6H78_RS05510 (I6H78_05510) tsf 1132334..1133374 (+) 1041 WP_000808056.1 translation elongation factor Ts -
  I6H78_RS05515 (I6H78_05515) cysK 1133478..1134404 (-) 927 WP_061853334.1 cysteine synthase A -
  I6H78_RS05520 (I6H78_05520) - 1134501..1134944 (-) 444 WP_084922193.1 PH domain-containing protein -
  I6H78_RS05525 (I6H78_05525) - 1134959..1135594 (-) 636 WP_198459045.1 YigZ family protein -
  I6H78_RS05530 (I6H78_05530) comFA/cflA 1135651..1136949 (+) 1299 WP_198459046.1 DEAD/DEAH box helicase Machinery gene
  I6H78_RS05535 (I6H78_05535) comFC/cflB 1136946..1137608 (+) 663 WP_198459047.1 ComF family protein Machinery gene
  I6H78_RS05540 (I6H78_05540) hpf 1137688..1138236 (+) 549 WP_198459048.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  I6H78_RS05545 (I6H78_05545) tnpA 1138433..1138897 (+) 465 WP_198459049.1 IS200/IS605 family transposase -
  I6H78_RS05550 (I6H78_05550) - 1139074..1140252 (+) 1179 WP_198460230.1 acetyl-CoA C-acetyltransferase -

Sequence

Protein


Download         Length: 432 a.a.        Molecular weight: 49554.34 Da        Isoelectric Point: 8.5135

>NTDB_id=516972 I6H78_RS05530 WP_198459046.1 1135651..1136949(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1021]
MKVNPNYLGRLFTEKELTEEERQVAVKLPAMRKEKGKLFCQRCNSPIQEEWYLPIGAYYCRECLLMKRVRSDQALYYFPQ
EDFPKQDVLKWRSQLTPSQGKVSEGLIRAVEKKEPTLVHAVTGAGKTEMIYQVVSKVIDDGGAVCLASPRIDVCLELYKR
LQNDFACDIALLHGESEPYFRTPLVIATTHQLLKFYHAFDLLIVDEVDAFPYVDNTMLYYAVKNSVKEDGLRIFLTATST
DELDRKVRTGELKRLSLPRRFHGNPLIIPKPVWLSDFNRCLEKNQLSTKLKTYIEKQRRTGYPLLIFASEIKKGEKLKEI
LQEQYPNENIGFVSSVTEDRLEQVQAFRDGELTILISTTILERGVTFPCVDVFVVEANHRLFTKSSLIQIGGRVGRSMDR
PTGELLFFHDGLNASIKKAIKEIKQTNKEAGL

Nucleotide


Download         Length: 1299 bp        

>NTDB_id=516972 I6H78_RS05530 WP_198459046.1 1135651..1136949(+) (comFA/cflA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAAAGTAAATCCAAATTACCTCGGTCGCTTGTTTACTGAGAAAGAATTAACTGAAGAAGAACGACAGGTAGCAGTGAA
ACTGCCAGCAATGAGAAAAGAGAAGGGGAAACTGTTTTGTCAACGTTGTAACAGTCCGATTCAAGAAGAATGGTATTTGC
CTATTGGCGCTTACTATTGCAGGGAGTGTTTGCTGATGAAGCGAGTCAGGAGTGATCAAGCTTTATACTATTTTCCACAG
GAAGATTTTCCCAAGCAAGATGTTCTTAAATGGCGTAGTCAGTTAACCCCTTCTCAGGGAAAGGTATCAGAGGGGCTGAT
TCGAGCAGTTGAAAAGAAGGAACCGACTTTAGTTCATGCTGTGACAGGTGCTGGAAAGACAGAGATGATTTATCAAGTTG
TATCCAAAGTGATTGATGATGGTGGAGCAGTTTGTTTGGCAAGTCCTCGAATTGATGTGTGTTTGGAACTGTATAAGCGA
CTGCAGAATGACTTTGCTTGCGATATAGCGCTACTCCATGGCGAATCAGAGCCCTATTTTCGAACTCCCTTAGTAATTGC
AACAACTCATCAGTTATTAAAATTTTATCATGCTTTTGATTTGTTGATAGTGGATGAGGTAGATGCCTTTCCTTATGTTG
ACAACACTATGCTTTACTATGCTGTAAAGAATAGTGTAAAGGAGGATGGATTGAGGATATTCCTTACGGCAACTTCTACA
GATGAGTTAGATAGGAAGGTTCGCACAGGGGAATTAAAAAGATTAAGCTTGCCGAGACGGTTTCATGGAAATCCTTTGAT
TATTCCTAAACCAGTCTGGTTATCGGATTTTAATCGCTGTTTAGAGAAAAATCAATTGTCAACCAAGTTAAAGACTTATA
TTGAGAAACAGAGAAGAACAGGTTATCCCTTACTGATTTTTGCATCAGAGATTAAGAAAGGCGAAAAACTAAAAGAAATC
TTGCAGGAGCAGTACCCGAATGAGAATATCGGCTTTGTGTCTTCTGTGACAGAAGACCGATTAGAGCAGGTGCAAGCTTT
TCGAGATGGAGAACTAACAATACTGATCAGTACGACAATCTTGGAACGTGGGGTTACCTTCCCTTGTGTGGATGTTTTCG
TAGTAGAAGCTAATCATCGTCTCTTTACCAAGTCTAGCTTGATTCAGATTGGAGGACGTGTTGGGCGTAGTATGGACAGA
CCAACTGGTGAGTTGCTCTTTTTTCATGATGGATTAAATGCTTCCATAAAGAAGGCAATCAAGGAAATCAAGCAGACGAA
CAAGGAGGCGGGATTATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(292-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

89.815

100

0.898
  comFA/cflA Streptococcus pneumoniae Rx1

89.12

100

0.891
  comFA/cflA Streptococcus pneumoniae D39

89.12

100

0.891
  comFA/cflA Streptococcus pneumoniae R6

89.12

100

0.891
  comFA/cflA Streptococcus pneumoniae TIGR4

88.889

100

0.889
  comFA/cflA Streptococcus mitis SK321

88.889

100

0.889
  comFA Lactococcus lactis subsp. cremoris KW2

50.367

94.676

0.477
  comFA Latilactobacillus sakei subsp. sakei 23K

38.532

100

0.389