Detailed information NTG0516953

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: I6H78_RS04135
• Genome accession: NZ_CP066059
• Coordinates: 871466..872476 (-)
• Length: 336 a.a.
• NCBI ID: WP_001090635.1
• Uniprot ID: I0Q241
• Organism: Streptococcus oralis strain FDAARGOS_1021
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 866466..877476

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6H78_RS04110 (I6H78_04110)	-	866491..867705 (-)	1215	WP_000666454.1	pyridoxal phosphate-dependent aminotransferase	-
I6H78_RS04115 (I6H78_04115)	-	867850..868149 (-)	300	WP_198460164.1	hypothetical protein	-
I6H78_RS04120 (I6H78_04120)	-	868316..868768 (+)	453	WP_000079161.1	universal stress protein	-
I6H78_RS04125 (I6H78_04125)	-	868805..870190 (-)	1386	WP_198460165.1	Cof-type HAD-IIB family hydrolase	-
I6H78_RS04130 (I6H78_04130)	-	870256..871218 (+)	963	WP_198460166.1	asparaginase	-
I6H78_RS04135 (I6H78_04135)	ccpA	871466..872476 (-)	1011	WP_001090635.1	catabolite control protein A	Regulator
I6H78_RS04140 (I6H78_04140)	-	872682..872999 (+)	318	WP_000886046.1	DUF960 domain-containing protein	-
I6H78_RS04145 (I6H78_04145)	-	873050..874333 (-)	1284	WP_198460167.1	DUF308 domain-containing protein	-
I6H78_RS04150 (I6H78_04150)	folK	874326..875147 (-)	822	WP_198460168.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
I6H78_RS04155 (I6H78_04155)	folE	875295..875849 (-)	555	WP_061409803.1	GTP cyclohydrolase I FolE	-
I6H78_RS04160 (I6H78_04160)	-	875853..877151 (-)	1299	WP_198460169.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37214.23 Da
• Isoelectric Point: 5.5033

>NTDB_id=516953 I6H78_RS04135 WP_001090635.1 871466..872476(-) (ccpA) [Streptococcus oralis strain FDAARGOS_1021]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATIDAVSYLLKENEKIAFVSGPLVDDINGKVRLIGYKEALKKAGHSYSEGLVFESKYSYDDGYALAERLISSQ
ATAAVVTGDELAAGVLNGLADHGVSVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=516953 I6H78_RS04135 WP_001090635.1 871466..872476(-) (ccpA) [Streptococcus oralis strain FDAARGOS_1021]
ATGAACACAGATGATACAGTAACGATTTATGATGTCGCCCGTGAAGCAGGAGTTTCAATGGCAACAGTTAGCCGTGTCGT
TAATGGCAACAAGAATGTTAAAGAGAACACTCGAAAAAAAGTCCTAGAAGTGATTGATCGCTTGGACTATCGTCCAAATG
CGGTAGCACGTGGTTTGGCTAGCAAGAAAACAACGACAGTCGGAGTTGTGATTCCTAACATTACCAATGGTTATTTCTCA
ACACTTGCTAAGGGAATTGACGACATTGCTGAAATGTACAAGTATAACATTGTCCTTGCAAATAGTGATGAGGATGATGA
AAAGGAAGTTTCAGTGGTTAACACTCTCTTTTCAAAACAAGTCGATGGGATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAGTTCTCTCGTTCACGGACACCGGTTGTTCTTGCTGGTACTGTGGATGTTGAACACCAACTTCCAAGT
GTGAATATCGACTACAAACAAGCAACGATTGATGCCGTGAGCTATCTTCTCAAAGAAAATGAGAAAATTGCTTTTGTGAG
TGGACCACTCGTCGATGATATCAATGGCAAGGTTCGTTTGATTGGTTATAAGGAAGCCTTGAAAAAAGCTGGGCATTCTT
ATAGTGAGGGCTTGGTCTTTGAATCAAAATACAGCTATGACGATGGTTATGCCTTGGCAGAACGCTTGATTTCATCACAA
GCTACAGCCGCAGTTGTAACAGGTGATGAATTGGCGGCGGGTGTGTTGAATGGTTTGGCTGACCACGGTGTGTCTGTGCC
AGAAGAGTTTGAAATCATTACGACAGATGACTCTCAGATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGACCTAGGTGCTATCAGCATGCGTATGTTGACTAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCCTGCCTCATGGTTTGACAGAACGTCGCTCTACACGAAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

3D structure

• AlphaFold DB: I0Q241

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	94.345	100	0.943
ccpA	Streptococcus gordonii str. Challis substr. CH1	88.623	99.405	0.881
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568