Detailed information NTG0515379

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: JAN99_RS06950
• Genome accession: NZ_CP065927
• Coordinates: 1422701..1423702 (-)
• Length: 333 a.a.
• NCBI ID: WP_002985680.1
• Uniprot ID: A0A4U7H1B9
• Organism: Streptococcus pyogenes strain emm9ST603
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1417701..1428702

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JAN99_RS06935 (JAN99_06930)	thrS	1417871..1419814 (-)	1944	WP_002985672.1	threonine--tRNA ligase	-
JAN99_RS06940 (JAN99_06935)	-	1420236..1421570 (-)	1335	WP_002994187.1	glycosyltransferase family 4 protein	-
JAN99_RS06945 (JAN99_06940)	-	1421572..1422570 (-)	999	WP_111693054.1	glycosyltransferase family 4 protein	-
JAN99_RS06950 (JAN99_06945)	ccpA	1422701..1423702 (-)	1002	WP_002985680.1	catabolite control protein A	Regulator
JAN99_RS06955 (JAN99_06950)	-	1423876..1424961 (+)	1086	WP_111693053.1	Xaa-Pro peptidase family protein	-
JAN99_RS06960 (JAN99_06955)	-	1425010..1425675 (+)	666	WP_111693052.1	NAD(P)H-dependent oxidoreductase	-
JAN99_RS06965 (JAN99_06960)	-	1425686..1426063 (+)	378	WP_002985686.1	VOC family protein	-
JAN99_RS06970 (JAN99_06965)	-	1426208..1427134 (+)	927	WP_047235928.1	glycosyltransferase family 2 protein	-
JAN99_RS06975 (JAN99_06970)	-	1427345..1428028 (+)	684	WP_023078761.1	DUF969 domain-containing protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36713.83 Da
• Isoelectric Point: 5.9985

>NTDB_id=515379 JAN99_RS06950 WP_002985680.1 1422701..1423702(-) (ccpA) [Streptococcus pyogenes strain emm9ST603]
MNTDDTITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIANSYFS
ILAKGIDDIAAMYKYNIVLASSDEDDDKEVNVVNTLFAKQVDGIIFMGHHLTEKIRAEFSRSRTPVVLAGTVDLDHQLPS
VNIDYRAAVSNVVDILAENHKCIAFVSGPLIDDINGKVRLAGYKEGLKHNKLDFKEGLVFEANYSYKEGFELAQRVINSG
ATAAYVAEDELAAGLLNGLFEAGKRVPEDFEIITSNDSPVVQYTRPNLSSISQPVYDLGAVSMRMLTKIMNKEELEEKEI
LLNHGIKKRGTTK

Nucleotide

• Length: 1002 bp

>NTDB_id=515379 JAN99_RS06950 WP_002985680.1 1422701..1423702(-) (ccpA) [Streptococcus pyogenes strain emm9ST603]
ATGAATACAGATGATACCATTACAATTTATGATGTTGCCCGTGAAGCTGGTGTTTCAATGGCAACCGTTAGTCGTGTTGT
TAATGGCAATAAAAATGTTAAGGAAAATACACGTAAGAAAGTTTTAGAAGTTATTGATCGCCTTGACTATCGTCCCAATG
CTGTCGCGCGTGGTCTCGCCAGCAAAAAGACAACAACCGTTGGCGTTGTGATTCCAAATATTGCAAATAGTTATTTTTCT
ATCTTAGCTAAGGGTATTGACGATATCGCCGCTATGTACAAATATAATATTGTGCTTGCCTCCAGTGATGAAGATGATGA
CAAGGAGGTTAATGTTGTCAATACCCTTTTTGCCAAGCAAGTGGATGGTATTATTTTTATGGGGCATCACTTGACAGAAA
AAATCCGGGCCGAATTTTCACGCTCTCGTACTCCAGTTGTTTTGGCAGGAACTGTAGATCTTGATCATCAATTACCAAGC
GTCAACATTGACTATAGAGCTGCGGTGTCAAACGTTGTTGATATTTTAGCTGAAAATCATAAGTGTATCGCTTTTGTGTC
AGGACCACTCATTGATGATATCAATGGTAAAGTGCGCTTAGCAGGTTACAAAGAAGGGTTGAAGCACAATAAGCTTGACT
TCAAAGAAGGTCTTGTTTTTGAAGCGAACTATTCTTATAAAGAAGGATTTGAATTGGCGCAGCGCGTCATTAACTCAGGA
GCAACAGCGGCTTATGTGGCTGAAGATGAATTGGCAGCAGGCCTTTTAAACGGCTTGTTTGAAGCAGGTAAACGCGTACC
AGAGGACTTTGAAATCATCACTAGCAACGATTCACCAGTGGTTCAATACACTCGTCCCAATTTGAGTTCTATCAGTCAAC
CTGTTTATGACTTAGGTGCTGTTAGCATGCGGATGTTGACTAAAATCATGAACAAAGAAGAGTTGGAAGAAAAAGAAATT
CTTTTGAATCATGGTATTAAAAAACGTGGGACAACTAAGTAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (177-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: A0A4U7H1B9

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	78.078	100	0.781
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	56.193	99.399	0.559