Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KX728_RS07640 Genome accession   NZ_CP079724
Coordinates   1560096..1560728 (-) Length   210 a.a.
NCBI ID   WP_215804360.1    Uniprot ID   -
Organism   Streptococcus oralis strain 34     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1555096..1565728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KX728_RS07625 (KX728_07620) recD/recD2/recDB 1555648..1558017 (+) 2370 WP_215804363.1 ATP-dependent RecD-like DNA helicase Machinery gene
  KX728_RS07630 (KX728_07625) tig 1558065..1559348 (-) 1284 WP_215804362.1 trigger factor -
  KX728_RS07635 (KX728_07630) - 1559439..1560095 (-) 657 WP_215804361.1 DNA alkylation repair protein -
  KX728_RS07640 (KX728_07635) vraR 1560096..1560728 (-) 633 WP_215804360.1 response regulator transcription factor Regulator
  KX728_RS07645 (KX728_07640) - 1560738..1561736 (-) 999 WP_215804359.1 sensor histidine kinase -
  KX728_RS07650 (KX728_07645) liaF 1561733..1562431 (-) 699 WP_215804358.1 cell wall-active antibiotics response protein LiaF -
  KX728_RS07655 (KX728_07650) fni 1562598..1563599 (-) 1002 WP_042767917.1 type 2 isopentenyl-diphosphate Delta-isomerase -
  KX728_RS07660 (KX728_07655) - 1563583..1564590 (-) 1008 WP_215804357.1 phosphomevalonate kinase -
  KX728_RS07665 (KX728_07660) mvaD 1564577..1565530 (-) 954 WP_215804356.1 diphosphomevalonate decarboxylase -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23570.18 Da        Isoelectric Point: 4.8942

>NTDB_id=514651 KX728_RS07640 WP_215804360.1 1560096..1560728(-) (vraR) [Streptococcus oralis strain 34]
MKILLVDDHEMVRLGLKSYFDLQDDVEVVGEAANGAQGIDLALKLRPDVIVMDIVMPEMNGIDATLAILKEWPEAKILIV
TSYLDNEKIMPVLNAGAKGYMLKTSSADELLHAVRKVAAGELAIEQEVSKKVEYHRNHIELHEELTARERDVLQLIAKGY
ENQRIADELFISLKTVKTHVSNILAKLEVSDRTQAAVYAFQHHLVGQEDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=514651 KX728_RS07640 WP_215804360.1 1560096..1560728(-) (vraR) [Streptococcus oralis strain 34]
ATGAAAATTTTACTTGTAGATGACCATGAAATGGTTCGATTGGGCTTGAAAAGCTATTTTGATCTCCAAGACGATGTGGA
AGTTGTGGGCGAGGCTGCCAATGGGGCTCAAGGTATTGACTTGGCCTTGAAACTGCGTCCAGATGTCATCGTCATGGATA
TAGTCATGCCTGAGATGAATGGGATTGACGCGACCTTAGCCATCCTGAAAGAATGGCCTGAAGCCAAGATTTTGATTGTA
ACTTCTTACTTGGACAATGAAAAAATTATGCCGGTCTTGAATGCGGGTGCCAAAGGTTACATGCTCAAGACTTCTAGTGC
AGACGAACTGCTTCATGCCGTCCGCAAGGTGGCTGCTGGAGAGCTGGCTATTGAACAAGAGGTCAGCAAAAAGGTCGAAT
ACCACCGCAATCATATAGAGCTTCATGAAGAACTGACTGCGCGTGAGCGAGACGTGCTTCAACTCATCGCCAAGGGCTAT
GAAAATCAGCGCATTGCAGATGAACTCTTTATCTCCCTAAAGACGGTGAAGACCCATGTGTCCAACATCCTAGCCAAGCT
TGAGGTCAGCGATCGCACTCAGGCTGCAGTCTATGCCTTTCAGCACCACTTGGTAGGGCAGGAGGATTTTTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(3-115)

Bacterial regulatory proteins, luxR family (GerE)

(145-199)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

51.456

98.095

0.505
  degU Bacillus subtilis subsp. subtilis str. 168

38.393

100

0.41