Detailed information NTG0513879

Bioinformatically predicted

Overview

• Name: pilU
• Type: Machinery gene
• Locus tag: KWY98_RS04185
• Genome accession: NZ_CP078119
• Coordinates: 803754..804980 (+)
• Length: 408 a.a.
• NCBI ID: WP_003690199.1
• Uniprot ID: -
• Organism: Neisseria gonorrhoeae strain 1291
• Function: mediate the depolymerization of the type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 798754..809980

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KWY98_RS04160 (KWY98_04160)	dksA	799930..800346 (-)	417	WP_003690204.1	RNA polymerase-binding protein DksA	-
KWY98_RS04165 (KWY98_04165)	proC	800494..801303 (-)	810	WP_225577382.1	pyrroline-5-carboxylate reductase	-
KWY98_RS04170 (KWY98_04170)	-	801334..801741 (-)	408	WP_003690202.1	hypothetical protein	-
KWY98_RS04175 (KWY98_04175)	-	801741..802427 (-)	687	WP_003690201.1	YggS family pyridoxal phosphate-dependent enzyme	-
KWY98_RS04180 (KWY98_04180)	pilT	802547..803590 (+)	1044	WP_003690200.1	type IV pilus twitching motility protein PilT	Machinery gene
KWY98_RS04185 (KWY98_04185)	pilU	803754..804980 (+)	1227	WP_003690199.1	PilT/PilU family type 4a pilus ATPase	Machinery gene
KWY98_RS04190 (KWY98_04190)	yccS	805097..807247 (+)	2151	WP_003690198.1	YccS family putative transporter	-
KWY98_RS04195 (KWY98_04195)	-	808179..808463 (-)	285	WP_003701816.1	GIY-YIG nuclease family protein	-
KWY98_RS04200 (KWY98_04200)	-	809107..809391 (-)	285	WP_003692093.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 408 a.a.
• Molecular weight: 45672.29 Da
• Isoelectric Point: 7.3203

>NTDB_id=513879 KWY98_RS04185 WP_003690199.1 803754..804980(+) (pilU) [Neisseria gonorrhoeae strain 1291]
MNTDNLHDILDETVQVYSQKKQSRSETPAEIGTHFHPLLDRLCETAEAQNASDILISKGFPPSLKINSALTPQPQKALTG
EETAAIAASTMNAEQSEIFRRDGEINYSVQSRSGTRYRANAYHSQGSAGLVLRRINHVIPQMRELGLPEKLKDLAVAPRG
LLIIVGPTGSGKSTTMATMLEHRNKTLPGHIVTIEDPIEFIYKPRRCIFTQREIGVDTINWQTAVQNAMRQSPDVVCIGE
VRSRESMEYAMQLAQTGHLCIFTLHANTAPQSLERILNFYPKEQHNQILIDIALNLTGIICQRLALKKDKTGRTAVVDLL
INTPAIQDFILKGDLMNISKIMETAKTDGMQTMDQNLFELYRHGIISYEEALRQSVSANNLRLHIQLHKEGKTPELLYDR
VNGLNLIS

Nucleotide

• Length: 1227 bp

>NTDB_id=513879 KWY98_RS04185 WP_003690199.1 803754..804980(+) (pilU) [Neisseria gonorrhoeae strain 1291]
ATGAATACCGATAACCTGCACGACATCTTGGACGAAACGGTTCAAGTGTATTCTCAAAAAAAACAAAGCCGATCCGAAAC
CCCGGCCGAAATCGGCACACACTTCCACCCGCTGCTCGACCGCCTGTGCGAAACCGCAGAAGCACAAAACGCGTCCGACA
TCCTTATCAGCAAAGGATTCCCGCCCTCGTTGAAAATCAACAGCGCATTAACCCCGCAGCCGCAAAAGGCTCTGACGGGC
GAGGAAACCGCCGCCATCGCCGCATCGACGATGAACGCCGAACAATCGGAAATATTCCGGCGCGACGGCGAAATCAACTA
CTCCGTCCAATCGCGCAGCGGCACGCGCTACCGCGCCAACGCCTACCACAGCCAAGGCAGCGCAGGTTTGGTTTTGCGGC
GCATCAACCACGTCATCCCGCAAATGCGGGAATTGGGCTTGCCCGAAAAACTCAAAGACCTCGCCGTCGCACCGCGCGGG
CTGCTGATTATCGTCGGGCCTACCGGTTCGGGCAAATCCACCACGATGGCGACTATGCTCGAACACCGCAACAAAACCCT
GCCCGGCCATATCGTTACCATCGAAGACCCGATTGAGTTTATCTACAAACCGCGCCGCTGCATCTTTACCCAGCGCGAAA
TCGGCGTCGACACCATAAACTGGCAGACGGCGGTACAAAACGCTATGCGCCAATCCCCAGACGTGGTCTGTATCGGCGAA
GTCCGCAGCAGGGAAAGTATGGAATACGCGATGCAGCTCGCCCAAACCGGCCACCTGTGCATTTTTACGCTCCACGCCAA
CACCGCGCCGCAGTCGCTCGAACGCATACTCAACTTCTACCCCAAAGAACAGCACAACCAAATACTGATTGACATCGCCC
TCAATCTGACCGGCATCATCTGCCAACGCCTCGCCCTCAAAAAAGACAAAACGGGCAGGACGGCGGTTGTCGACTTGCTC
ATCAACACGCCCGCCATCCAAGACTTCATCCTGAAGGGCGACCTGATGAACATCAGTAAAATCATGGAAACCGCCAAAAC
CGACGGAATGCAGACGATGGACCAAAACCTTTTCGAACTGTACCGTCACGGCATCATCAGTTACGAAGAAGCCCTGCGCC
AGTCCGTTTCCGCCAACAACCTGCGATTGCACATCCAACTGCACAAAGAAGGCAAAACGCCCGAACTCCTTTACGACAGG
GTCAACGGTCTCAACCTCATTTCCTGA

Domains

Predicted by InterProScan.

• Type II/IV secretion system protein (T2SSE) (49-305)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilU	Acinetobacter baylyi ADP1	44.875	88.48	0.397
pilU	Pseudomonas stutzeri DSM 10701	44.944	87.255	0.392
pilU	Vibrio cholerae strain A1552	47.024	82.353	0.387