Detailed information NTG0513564

Bioinformatically predicted

Overview

• Name: dprA
• Type: Machinery gene
• Locus tag: I6G28_RS00295
• Genome accession: NZ_CP065726
• Coordinates: 45196..46389 (-)
• Length: 397 a.a.
• NCBI ID: WP_111727533.1
• Uniprot ID: A0A7T3EUI8
• Organism: Neisseria cinerea strain FDAARGOS_871
• Function: ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 40196..51389

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G28_RS00275 (I6G28_00275)	-	41275..41526 (-)	252	WP_003677924.1	YfhL family 4Fe-4S dicluster ferredoxin	-
I6G28_RS00280 (I6G28_00280)	rsmD	41648..42217 (-)	570	WP_107996484.1	16S rRNA (guanine(966)-N(2))-methyltransferase RsmD	-
I6G28_RS00285 (I6G28_00285)	topA	42326..44632 (-)	2307	WP_111727534.1	type I DNA topoisomerase	-
I6G28_RS00290 (I6G28_00290)	-	44712..45173 (-)	462	WP_108044376.1	DUF494 domain-containing protein	-
I6G28_RS00295 (I6G28_00295)	dprA	45196..46389 (-)	1194	WP_111727533.1	DNA-processing protein DprA	Machinery gene
I6G28_RS00300 (I6G28_00300)	-	46481..47758 (-)	1278	WP_111727532.1	sigma-54-dependent transcriptional regulator	-
I6G28_RS00305 (I6G28_00305)	-	47763..49868 (-)	2106	WP_111727531.1	sensor histidine kinase	-
I6G28_RS00310 (I6G28_00310)	-	49868..50464 (-)	597	WP_003677947.1	DUF4390 domain-containing protein	-

Sequence

Protein

• Length: 397 a.a.
• Molecular weight: 42815.98 Da
• Isoelectric Point: 5.8227

>NTDB_id=513564 I6G28_RS00295 WP_111727533.1 45196..46389(-) (dprA) [Neisseria cinerea strain FDAARGOS_871]
MTENERFAWLQLAFTPYIGAESFLLLLHHFDSAQNALSAPAEQVAALIRHKQALEAWRGGDKRTVARQAAEAALEWEMRD
GCRLMLLRDDDFPEMLTQGITAPPVLFLRGNVQLLHKPSAAIVGSRHATPQAMRIAKDFGKSLGGQNIPVVSGMASGIDT
AAHQGALEAEGGTIAVWGTGIDRIYPPSNKNLAYEIAEKGLIVSEFPIGTRPYAGNFPRRNRLIAALSQVTLVVEAALES
GSLITARLAAEMGREVMAVPGSIDNPHSKGCHKLIKDGAKLVECLDDILHECPRLLQNEGASSYSINKGIPEKCITAVQT
ASDPPFSSEGKMPSEKTENRPVGGGILDRMGFDPVHPDVLAEQLGMPAADLYAELLELELDGSIAAMPGGRYQRIRT

Nucleotide

• Length: 1194 bp

>NTDB_id=513564 I6G28_RS00295 WP_111727533.1 45196..46389(-) (dprA) [Neisseria cinerea strain FDAARGOS_871]
ATGACAGAGAACGAACGTTTCGCATGGTTGCAGCTGGCTTTTACGCCCTATATCGGTGCGGAAAGTTTCTTGCTGCTGCT
GCACCATTTCGACAGTGCGCAAAATGCCCTGTCCGCACCGGCGGAACAGGTGGCGGCACTGATACGGCACAAACAGGCGC
TTGAGGCTTGGCGCGGCGGCGACAAACGTACTGTGGCACGGCAGGCCGCCGAAGCGGCATTGGAATGGGAAATGAGGGAC
GGATGCCGTCTGATGCTTCTGCGGGATGATGACTTTCCTGAAATGCTGACTCAGGGTATAACCGCGCCGCCGGTTTTGTT
TTTGCGCGGCAACGTGCAACTGCTGCACAAACCTTCCGCCGCTATCGTCGGCAGCCGTCATGCCACGCCGCAGGCAATGC
GAATTGCCAAAGATTTCGGCAAGTCGTTGGGCGGGCAAAATATCCCCGTTGTGTCAGGTATGGCTTCCGGTATCGATACT
GCCGCCCATCAGGGCGCACTGGAGGCAGAAGGCGGCACCATCGCCGTGTGGGGGACAGGTATAGACCGCATTTACCCGCC
GTCCAATAAAAACCTTGCCTATGAAATCGCCGAAAAAGGACTGATTGTCAGCGAGTTTCCCATCGGTACGCGGCCGTATG
CCGGCAATTTTCCGCGCCGCAACCGCCTGATTGCCGCACTGTCGCAAGTAACGCTGGTGGTTGAAGCCGCATTGGAATCC
GGTTCGCTGATTACTGCCAGATTGGCAGCGGAGATGGGGCGCGAAGTGATGGCGGTACCCGGCTCGATAGACAATCCACA
CAGTAAAGGCTGCCACAAACTGATTAAAGACGGCGCAAAATTGGTGGAATGCCTGGACGACATCCTTCACGAGTGTCCGC
GGCTCTTGCAAAATGAGGGTGCTTCATCATATTCTATAAATAAGGGAATACCTGAAAAGTGCATCACTGCCGTTCAGACG
GCATCTGACCCGCCGTTTTCGTCTGAAGGCAAAATGCCGTCTGAAAAGACGGAGAACCGACCCGTCGGCGGCGGTATCTT
GGACAGGATGGGTTTCGACCCGGTTCATCCCGATGTGCTTGCCGAGCAGTTGGGTATGCCTGCCGCAGACTTATACGCCG
AACTGTTGGAATTGGAACTGGACGGCAGCATTGCCGCCATGCCTGGCGGAAGATACCAGCGTATCCGAACCTGA

Domains

Predicted by InterproScan.

• DprA winged helix domain (DprA_WH) (345-390)

• DNA recombination-mediator protein A (DNA_processg_A) (79-283)

3D structure

• AlphaFold DB: A0A7T3EUI8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA	Neisseria meningitidis strain C311	92.191	100	0.922
dprA	Neisseria meningitidis MC58	92.191	100	0.922
dprA	Neisseria gonorrhoeae strain FA1090	85.642	100	0.856
dprA	Neisseria gonorrhoeae MS11	85.39	100	0.854
dprA	Vibrio cholerae strain A1552	37.594	100	0.378
dprA	Vibrio campbellii strain DS40M4	36.923	98.237	0.363