Detailed information NTG0513259

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: I6G42_RS00695
• Genome accession: NZ_CP065707
• Coordinates: 147814..148824 (-)
• Length: 336 a.a.
• NCBI ID: WP_038804599.1
• Uniprot ID: A0A3R9K0P0
• Organism: Streptococcus oralis strain FDAARGOS_885
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 142814..153824

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G42_RS00670 (I6G42_00670)	-	143036..144250 (-)	1215	WP_038804594.1	pyridoxal phosphate-dependent aminotransferase	-
I6G42_RS00675 (I6G42_00675)	-	144394..144693 (-)	300	WP_038804595.1	hypothetical protein	-
I6G42_RS00680 (I6G42_00680)	-	144860..145312 (+)	453	WP_000079159.1	universal stress protein	-
I6G42_RS00685 (I6G42_00685)	-	145348..146733 (-)	1386	WP_038804597.1	Cof-type HAD-IIB family hydrolase	-
I6G42_RS00690 (I6G42_00690)	-	146799..147761 (+)	963	WP_038804598.1	asparaginase	-
I6G42_RS00695 (I6G42_00695)	ccpA	147814..148824 (-)	1011	WP_038804599.1	catabolite control protein A	Regulator
I6G42_RS00700 (I6G42_00700)	-	149034..149351 (+)	318	WP_000886039.1	DUF960 domain-containing protein	-
I6G42_RS00705 (I6G42_00705)	folK	149398..150210 (-)	813	WP_038804600.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
I6G42_RS00710 (I6G42_00710)	folE	150253..150807 (-)	555	WP_038804601.1	GTP cyclohydrolase I FolE	-
I6G42_RS00715 (I6G42_00715)	-	150764..152110 (-)	1347	WP_038804602.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-
I6G42_RS00720 (I6G42_00720)	folP	152112..153056 (-)	945	WP_038804603.1	dihydropteroate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37215.31 Da
• Isoelectric Point: 5.4980

>NTDB_id=513259 I6G42_RS00695 WP_038804599.1 147814..148824(-) (ccpA) [Streptococcus oralis strain FDAARGOS_885]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDIEHQLPS
VNIDYKQATIDAVTHLLQENEKIAFVSGPLVDDINGKIRLIGYKEALKKAGIPYSEGLVFESKYSYNDGYALAERLVSSQ
ATAAVVTGDELAAGVLNGLADHGISVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=513259 I6G42_RS00695 WP_038804599.1 147814..148824(-) (ccpA) [Streptococcus oralis strain FDAARGOS_885]
ATGAACACAGATGATACAGTAACGATTTATGATGTTGCCCGTGAAGCTGGGGTTTCAATGGCAACTGTTAGCCGTGTAGT
GAATGGCAATAAGAACGTCAAAGAGAACACTCGTAAAAAAGTTCTAGAGGTGATTGATCGTCTTGACTACCGTCCAAATG
CGGTAGCGCGTGGTTTGGCCAGCAAGAAAACCACTACAGTTGGTGTTGTGATTCCAAATATCACTAATGGCTATTTTTCA
ACCCTAGCCAAGGGGATTGATGATATTGCAGAGATGTATAAGTACAATATCGTCCTAGCCAATAGTGATGAAGACGATGA
AAAAGAAGTTTCAGTAGTTAATACTCTCTTTTCAAAACAGGTTGACGGGATCATTTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAATTCTCTCGTTCACGGACACCAGTTGTCCTTGCAGGAACGGTGGATATCGAACACCAGTTGCCAAGT
GTTAATATTGACTACAAACAAGCAACGATTGATGCAGTAACTCATTTGCTTCAGGAAAATGAAAAGATTGCCTTTGTCAG
TGGGCCACTTGTTGATGATATCAATGGTAAAATTCGATTGATTGGTTACAAGGAAGCTTTGAAAAAGGCAGGAATCCCTT
ATAGCGAGGGCTTGGTATTTGAGTCTAAATACAGCTATAATGATGGCTATGCCTTGGCAGAGCGCTTGGTTTCTTCACAG
GCTACAGCCGCGGTTGTGACAGGTGATGAATTGGCTGCGGGTGTGTTAAATGGCTTGGCAGATCACGGTATTTCTGTACC
AGAAGAGTTTGAAATCATCACGACAGATGATTCTCAGATTGCACGATTCACTCGTCCAAATCTGACAACGATTGCCCAAC
CTCTTTATGATCTAGGTGCTATCAGCATGCGTATGTTGACCAAAATCATGCACAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCTTGCCTCACGGTTTAACAGAACGTCGTTCAACACGCAAACGTAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A3R9K0P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	92.262	100	0.923
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568