Detailed information NTG0513245

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: I6G43_RS08845
• Genome accession: NZ_CP065706
• Coordinates: 1840920..1841930 (-)
• Length: 336 a.a.
• NCBI ID: WP_038804599.1
• Uniprot ID: A0A3R9K0P0
• Organism: Streptococcus oralis strain FDAARGOS_886
• Function: regulate comCDE transcription and transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1835920..1846930

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I6G43_RS08820 (I6G43_08820)	-	1836153..1837367 (-)	1215	WP_000666480.1	pyridoxal phosphate-dependent aminotransferase	-
I6G43_RS08825 (I6G43_08825)	-	1837512..1837811 (-)	300	WP_038805805.1	hypothetical protein	-
I6G43_RS08830 (I6G43_08830)	-	1837978..1838430 (+)	453	WP_000079159.1	universal stress protein	-
I6G43_RS08835 (I6G43_08835)	-	1838466..1839851 (-)	1386	WP_000453130.1	Cof-type HAD-IIB family hydrolase	-
I6G43_RS08840 (I6G43_08840)	-	1839917..1840879 (+)	963	WP_001124804.1	asparaginase	-
I6G43_RS08845 (I6G43_08845)	ccpA	1840920..1841930 (-)	1011	WP_038804599.1	catabolite control protein A	Regulator
I6G43_RS08850 (I6G43_08850)	-	1842140..1842457 (+)	318	WP_038805930.1	DUF960 domain-containing protein	-
I6G43_RS08855 (I6G43_08855)	-	1842508..1843791 (-)	1284	WP_001125353.1	DUF308 domain-containing protein	-
I6G43_RS08860 (I6G43_08860)	folK	1843784..1844605 (-)	822	WP_000372501.1	2-amino-4-hydroxy-6- hydroxymethyldihydropteridine diphosphokinase	-
I6G43_RS08865 (I6G43_08865)	folE	1844648..1845202 (-)	555	WP_000380934.1	GTP cyclohydrolase I FolE	-
I6G43_RS08870 (I6G43_08870)	-	1845183..1846505 (-)	1323	WP_000659084.1	bifunctional folylpolyglutamate synthase/dihydrofolate synthase	-

Sequence

Protein

• Length: 336 a.a.
• Molecular weight: 37215.31 Da
• Isoelectric Point: 5.4980

>NTDB_id=513245 I6G43_RS08845 WP_038804599.1 1840920..1841930(-) (ccpA) [Streptococcus oralis strain FDAARGOS_886]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITNGYFS
TLAKGIDDIAEMYKYNIVLANSDEDDEKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDIEHQLPS
VNIDYKQATIDAVTHLLQENEKIAFVSGPLVDDINGKIRLIGYKEALKKAGIPYSEGLVFESKYSYNDGYALAERLVSSQ
ATAAVVTGDELAAGVLNGLADHGISVPEEFEIITTDDSQIARFTRPNLTTIAQPLYDLGAISMRMLTKIMHKEELEEREV
LLPHGLTERRSTRKRK

Nucleotide

• Length: 1011 bp

>NTDB_id=513245 I6G43_RS08845 WP_038804599.1 1840920..1841930(-) (ccpA) [Streptococcus oralis strain FDAARGOS_886]
ATGAACACAGATGATACAGTAACGATTTATGATGTTGCCCGTGAAGCTGGGGTTTCAATGGCAACTGTTAGCCGTGTAGT
GAATGGCAATAAGAACGTCAAAGAGAATACTCGTAAAAAAGTTCTAGAGGTGATCGATCGTCTTGACTACCGTCCAAATG
CGGTAGCGCGTGGCTTGGCCAGCAAGAAAACCACGACAGTTGGTGTTGTGATTCCAAATATCACCAATGGCTATTTTTCA
ACCCTAGCCAAGGGGATTGATGATATTGCAGAGATGTATAAGTACAATATCGTCCTAGCCAACAGTGATGAAGACGATGA
AAAAGAAGTTTCAGTAGTTAATACTCTCTTTTCAAAACAAGTTGATGGTATTATCTTTATGGGCTATCACTTGACTGAAA
AGATTCGTTCAGAATTTTCTCGTTCTCGGACACCAGTTGTCCTTGCAGGAACGGTGGATATCGAACACCAGTTGCCAAGT
GTTAATATTGACTACAAACAAGCAACGATTGATGCAGTAACTCATTTGCTTCAGGAAAATGAAAAGATTGCCTTTGTCAG
CGGGCCACTTGTTGATGATATCAACGGCAAAATTCGATTGATTGGTTACAAGGAAGCTTTGAAAAAGGCAGGAATCCCTT
ATAGCGAGGGCTTGGTATTTGAGTCTAAATACAGCTATAATGATGGCTATGCCTTGGCAGAGCGCTTGGTTTCTTCACAG
GCTACAGCTGCAGTTGTGACAGGTGATGAATTGGCTGCGGGTGTGTTAAATGGCTTGGCAGATCACGGTATTTCTGTACC
GGAAGAGTTTGAAATCATCACGACAGATGATTCTCAAATTGCACGATTCACTCGTCCAAACTTGACTACTATTGCCCAAC
CTCTTTATGACCTAGGCGCTATCAGCATGCGTATGTTGACCAAGATTATGCATAAGGAAGAGTTGGAAGAACGTGAAGTT
CTCCTGCCTCACGGTTTGACAGAACGCCGTTCGACACGAAAACGCAAATAG

Domains

Predicted by InterproScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: A0A3R9K0P0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus pneumoniae D39	92.262	100	0.923
ccpA	Streptococcus gordonii str. Challis substr. CH1	86.826	99.405	0.863
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	57.704	98.512	0.568