Detailed information NTG0511342

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: ST4147_RS08650
• Genome accession: NZ_CP065504
• Coordinates: 1657921..1658358 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 4147
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1652921..1663358

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4147_RS08615 (ST4147_08590)	-	1652975..1653637 (-)	663	WP_011227583.1	type II CAAX endopeptidase family protein	-
ST4147_RS08620 (ST4147_08595)	-	1653740..1654188 (-)	449	Protein_1640	CAAX protease	-
ST4147_RS08625	-	1654262..1654687 (-)	426	WP_041827107.1	CPBP family intramembrane glutamic endopeptidase	-
ST4147_RS08630 (ST4147_08605)	-	1654930..1655127 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
ST4147_RS08635 (ST4147_08610)	-	1655376..1656569 (-)	1194	WP_022096898.1	acetate kinase	-
ST4147_RS08640 (ST4147_08615)	comYH	1656625..1657581 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
ST4147_RS08645 (ST4147_08620)	comGG	1657626..1657943 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
ST4147_RS08650 (ST4147_08625)	comYF	1657921..1658358 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
ST4147_RS08655 (ST4147_08630)	comGE	1658342..1658635 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
ST4147_RS08660 (ST4147_08635)	comYD	1658607..1659035 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
ST4147_RS08665 (ST4147_08640)	comYC	1658995..1659321 (-)	327	WP_002946126.1	competence type IV pilus major pilin ComGC	Machinery gene
ST4147_RS08670 (ST4147_08645)	comYB	1659318..1660418 (-)	1101	WP_148148900.1	competence type IV pilus assembly protein ComGB	Machinery gene
ST4147_RS08675 (ST4147_08650)	comGA/cglA/cilD	1660300..1661241 (-)	942	WP_011226629.1	competence type IV pilus ATPase ComGA	Machinery gene
ST4147_RS08680 (ST4147_08655)	-	1661322..1661684 (-)	363	WP_011226630.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=511342 ST4147_RS08650 WP_014608742.1 1657921..1658358(-) (comYF) [Streptococcus thermophilus strain 4147]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=511342 ST4147_RS08650 WP_014608742.1 1657921..1658358(-) (comYF) [Streptococcus thermophilus strain 4147]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441