Detailed information NTG0511314

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST4147_RS03275
• Genome accession: NZ_CP065504
• Coordinates: 603100..604101 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 4147
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 598100..609101

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4147_RS03255 (ST4147_03225)	smpB	599206..599670 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST4147_RS03260 (ST4147_03230)	-	599824..601230 (+)	1407	WP_011227013.1	Cof-type HAD-IIB family hydrolase	-
ST4147_RS03265 (ST4147_03235)	-	601232..601597 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST4147_RS03270 (ST4147_03240)	-	601700..602785 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
ST4147_RS03275 (ST4147_03245)	ccpA	603100..604101 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST4147_RS03280 (ST4147_03250)	-	604160..604357 (+)	198	WP_011225705.1	hypothetical protein	-
ST4147_RS03285 (ST4147_03255)	-	604463..605227 (+)	765	WP_011225706.1	MmcQ/YjbR family DNA-binding protein	-
ST4147_RS03290 (ST4147_03260)	-	605242..606357 (+)	1116	WP_011227015.1	glycerate kinase	-
ST4147_RS03295 (ST4147_03265)	-	606396..606851 (-)	456	WP_002950250.1	YueI family protein	-
ST4147_RS03300 (ST4147_03270)	eno	607060..608364 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
ST4147_RS03305 (ST4147_03275)	-	608516..608700 (-)	185	Protein_589	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=511314 ST4147_RS03275 WP_004197422.1 603100..604101(+) (ccpA) [Streptococcus thermophilus strain 4147]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=511314 ST4147_RS03275 WP_004197422.1 603100..604101(+) (ccpA) [Streptococcus thermophilus strain 4147]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547