Detailed information NTG0511219

Bioinformatically predicted

Overview

• Name: comYF
• Type: Machinery gene
• Locus tag: STT128_RS08880
• Genome accession: NZ_CP065500
• Coordinates: 1719114..1719551 (-)
• Length: 145 a.a.
• NCBI ID: WP_014608742.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain ST128
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1714114..1724551

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STT128_RS08840 (STT128_08920)	-	1714178..1714840 (-)	663	WP_011681679.1	type II CAAX endopeptidase family protein	-
STT128_RS08845 (STT128_08925)	-	1714937..1715380 (-)	444	WP_011681680.1	hypothetical protein	-
STT128_RS08850	-	1715454..1715879 (-)	426	WP_014608739.1	CPBP family intramembrane glutamic endopeptidase	-
STT128_RS08855	-	1715836..1716111 (-)	276	WP_011681681.1	hypothetical protein	-
STT128_RS08860 (STT128_08935)	-	1716123..1716320 (-)	198	WP_011681682.1	helix-turn-helix transcriptional regulator	-
STT128_RS08865 (STT128_08940)	-	1716569..1717762 (-)	1194	WP_014608740.1	acetate kinase	-
STT128_RS08870 (STT128_08945)	comYH	1717818..1718774 (-)	957	WP_011226622.1	class I SAM-dependent methyltransferase	Machinery gene
STT128_RS08875 (STT128_08950)	comGG	1718819..1719136 (-)	318	WP_002952035.1	competence type IV pilus minor pilin ComGG	-
STT128_RS08880 (STT128_08955)	comYF	1719114..1719551 (-)	438	WP_014608742.1	competence type IV pilus minor pilin ComGF	Machinery gene
STT128_RS08885 (STT128_08960)	comGE	1719535..1719828 (-)	294	WP_011226625.1	competence type IV pilus minor pilin ComGE	-
STT128_RS08890 (STT128_08965)	comYD	1719800..1720228 (-)	429	WP_011226626.1	competence type IV pilus minor pilin ComGD	Machinery gene
STT128_RS08895 (STT128_08970)	comYC	1720188..1720514 (-)	327	WP_014727724.1	competence type IV pilus major pilin ComGC	Machinery gene
STT128_RS08900 (STT128_08975)	comYB	1720511..1721611 (-)	1101	WP_120764773.1	competence type IV pilus assembly protein ComGB	Machinery gene
STT128_RS08905 (STT128_08980)	comGA/cglA/cilD	1721493..1722434 (-)	942	WP_022096896.1	competence type IV pilus ATPase ComGA	Machinery gene
STT128_RS08910 (STT128_08985)	-	1722515..1722877 (-)	363	WP_014622006.1	DUF1033 family protein	-

Sequence

Protein

• Length: 145 a.a.
• Molecular weight: 16505.05 Da
• Isoelectric Point: 8.9784

>NTDB_id=511219 STT128_RS08880 WP_014608742.1 1719114..1719551(-) (comYF) [Streptococcus thermophilus strain ST128]
MYLSSKLRAFTLLECLVALLVIAGSVQVYQGLTTVLVSNVKQVRQQENQDWLLFVQQMEAELEGCQLVKVEWNKLYVKKD
NQDLAFGLSSASDFRKTNADGRGYQPMLFDVKSSKVSQKNQIVTIQVTLKNELQRSFVYAFEKTG

Nucleotide

• Length: 438 bp

>NTDB_id=511219 STT128_RS08880 WP_014608742.1 1719114..1719551(-) (comYF) [Streptococcus thermophilus strain ST128]
ATGTATCTAAGCAGTAAGCTGCGTGCCTTTACCCTCTTGGAATGTCTAGTGGCCTTGTTGGTCATTGCTGGCTCAGTTCA
AGTTTATCAAGGGTTAACCACTGTACTTGTGAGTAATGTTAAGCAGGTAAGACAACAAGAAAACCAAGATTGGCTTCTAT
TTGTTCAACAAATGGAGGCAGAATTAGAAGGATGTCAGTTGGTCAAGGTAGAGTGGAACAAACTCTATGTCAAGAAGGAT
AATCAAGACTTGGCTTTTGGTCTTTCAAGTGCCTCTGATTTTCGAAAAACAAATGCTGATGGTCGAGGTTATCAACCAAT
GCTTTTCGATGTCAAATCTAGTAAGGTAAGTCAAAAGAACCAGATAGTTACCATCCAAGTGACTCTTAAAAATGAACTAC
AAAGGAGTTTTGTTTATGCTTTTGAAAAAACAGGTTAG

Domains

Predicted by InterproScan.

• Putative Competence protein ComGF (ComGF) (39-134)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comYF	Streptococcus mutans UA140	58.865	97.241	0.572
comYF	Streptococcus mutans UA159	58.156	97.241	0.566
comGF/cglF	Streptococcus pneumoniae D39	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae Rx1	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae R6	47.857	96.552	0.462
comGF/cglF	Streptococcus pneumoniae TIGR4	47.857	96.552	0.462
comGF/cglF	Streptococcus mitis NCTC 12261	46.099	97.241	0.448
comGF/cglF	Streptococcus mitis SK321	45.39	97.241	0.441
comGF	Lactococcus lactis subsp. cremoris KW2	46.043	95.862	0.441