Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   STR1_RS05485 Genome accession   NZ_CP065486
Coordinates   1054542..1055882 (-) Length   446 a.a.
NCBI ID   WP_084830671.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain R1     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1049542..1060882
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STR1_RS05460 (STR1_05525) yidA 1049802..1050611 (+) 810 WP_011226081.1 sugar-phosphatase -
  STR1_RS05465 (STR1_05530) - 1050613..1051836 (+) 1224 WP_095559388.1 aminoacyltransferase -
  STR1_RS05470 (STR1_05535) - 1051845..1053101 (-) 1257 WP_198362548.1 ISL3-like element ISSth1 family transposase -
  STR1_RS05475 (STR1_05540) - 1053303..1053664 (-) 362 Protein_1035 YbaN family protein -
  STR1_RS05480 (STR1_05545) vicX 1053724..1054536 (-) 813 WP_011681204.1 MBL fold metallo-hydrolase Regulator
  STR1_RS05485 (STR1_05550) vicK 1054542..1055882 (-) 1341 WP_084830671.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STR1_RS05490 (STR1_05555) vicR 1055875..1056582 (-) 708 WP_095559389.1 response regulator YycF Regulator
  STR1_RS05495 (STR1_05560) - 1057104..1057871 (+) 768 WP_347128973.1 amino acid ABC transporter ATP-binding protein -
  STR1_RS05500 (STR1_05565) - 1057883..1058716 (+) 834 WP_011681208.1 transporter substrate-binding domain-containing protein -
  STR1_RS05505 (STR1_05570) - 1058734..1059432 (+) 699 WP_014608374.1 amino acid ABC transporter permease -
  STR1_RS05510 (STR1_05575) - 1059444..1060094 (+) 651 WP_095559390.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 50767.14 Da        Isoelectric Point: 5.3880

>NTDB_id=510543 STR1_RS05485 WP_084830671.1 1054542..1055882(-) (vicK) [Streptococcus thermophilus strain R1]
MTSIGLNITSFELALLFMLLFVAFYFIFLAYRDYQQVKNIRKLTKRVKSLMAGNYNEKLCIKGNSELLELANSLNDLSDV
FRLTHENLIQEKNRLSSVLSYMSDGVIATNRLGQITMINSTAQRLLNLDRETATQMSILDILDGENPYTYSELLSKTPEI
HLSRRDANDEFVTLRVNFALIRKESGFISGLVAVLHDATEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALNE
EIAPNFIKVSLDETNRMMRMISDLLALSRIDNKSTQLNVEMTNFTAFMTYILNRFGQIKSQETNPGKSYEIIRDYPVNSI
WVEIDTDKMTQVIDNILNNAIKYSPDGGKITVSMKTTDTQLIVSISDQGLGIPKKDLPLIFDRFYRVDKARSRAQGGTGL
GLSIAKEIVKQHNGFIWAKSEYGKGSTFTIVLPYDQDAMMVDEWEM

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=510543 STR1_RS05485 WP_084830671.1 1054542..1055882(-) (vicK) [Streptococcus thermophilus strain R1]
ATGACTAGTATTGGCTTAAATATTACAAGCTTTGAACTGGCCTTACTCTTTATGCTCCTCTTTGTTGCTTTCTATTTCAT
TTTTCTAGCTTATCGTGATTATCAACAGGTCAAAAATATCCGAAAGTTGACTAAGAGAGTCAAATCCCTTATGGCAGGTA
ATTATAATGAAAAATTATGCATAAAGGGAAATTCAGAGCTTTTAGAGCTAGCTAATAGCTTGAATGATTTGTCGGACGTC
TTTCGTTTGACACATGAAAATCTAATCCAGGAAAAAAACCGCTTATCATCTGTCCTTTCGTACATGAGTGACGGGGTTAT
TGCGACCAATCGCCTTGGTCAGATTACTATGATTAATAGTACTGCCCAACGTTTGTTGAATTTAGATCGCGAAACTGCGA
CTCAGATGTCTATTTTGGATATATTAGATGGTGAGAATCCCTATACCTATAGTGAATTGTTGTCTAAGACACCCGAAATC
CATCTGTCGCGTCGAGATGCTAACGATGAATTTGTGACGCTACGTGTTAATTTTGCATTAATTCGTAAGGAATCTGGTTT
TATTTCAGGTCTGGTAGCCGTTCTTCATGATGCCACTGAGCAGGAAAAAGAAGAGCGCGAACGCCGTCTCTTCGTATCAA
ATGTTAGTCACGAATTGCGGACGCCTTTAACTTCTGTGAAATCCTATCTTGAAGCGCTTGATGATGGTGCTCTCAACGAA
GAGATTGCTCCAAACTTTATCAAAGTTTCTTTAGATGAAACCAACCGCATGATGCGTATGATTTCTGACCTCTTGGCATT
ATCTCGAATTGACAATAAAAGCACACAGCTTAATGTTGAAATGACAAACTTTACAGCCTTTATGACCTATATCTTGAATC
GGTTTGGTCAAATTAAGAGTCAAGAAACTAATCCAGGTAAGTCTTATGAAATCATTCGAGATTACCCAGTAAACTCTATT
TGGGTGGAAATTGATACTGATAAGATGACCCAGGTCATAGATAATATACTTAATAATGCCATCAAGTATTCTCCTGATGG
TGGGAAAATTACAGTATCTATGAAAACGACAGACACTCAGTTGATTGTTTCTATTTCTGACCAAGGTTTAGGAATTCCTA
AAAAAGATTTACCTCTGATTTTTGACCGTTTTTACCGTGTTGATAAGGCCAGAAGTCGTGCTCAGGGTGGAACAGGACTT
GGCTTATCCATTGCAAAAGAAATTGTTAAACAACATAATGGCTTCATTTGGGCTAAGAGTGAGTATGGTAAGGGATCAAC
TTTTACAATTGTGCTTCCATATGACCAGGACGCAATGATGGTCGATGAATGGGAGATGTAG

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(208-272)

PAS fold (PAS)

(94-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(325-435)

HAMP domain (HAMP)

(37-79)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

74.638

92.825

0.693
  micB Streptococcus pneumoniae Cp1015

66.051

97.085

0.641