Detailed information NTG0510535

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: STR1_RS03220
• Genome accession: NZ_CP065486
• Coordinates: 612363..613364 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain R1
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 607363..618364

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STR1_RS03200 (STR1_03190)	smpB	608467..608931 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
STR1_RS03205 (STR1_03195)	-	609085..610491 (+)	1407	WP_095559289.1	Cof-type HAD-IIB family hydrolase	-
STR1_RS03210 (STR1_03200)	-	610493..610858 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
STR1_RS03215 (STR1_03205)	-	610961..612046 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
STR1_RS03220 (STR1_03210)	ccpA	612363..613364 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
STR1_RS03225 (STR1_03215)	-	613423..613620 (+)	198	WP_014608125.1	hypothetical protein	-
STR1_RS03230	-	613726..613950 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
STR1_RS03235 (STR1_03220)	-	613951..614490 (+)	540	WP_011680936.1	hypothetical protein	-
STR1_RS03240 (STR1_03225)	-	614503..615618 (+)	1116	WP_011680937.1	glycerate kinase	-
STR1_RS03245 (STR1_03230)	-	615665..616120 (-)	456	WP_095559290.1	YueI family protein	-
STR1_RS03250 (STR1_03235)	eno	616328..617632 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
STR1_RS03255 (STR1_03240)	-	617787..617971 (-)	185	Protein_592	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=510535 STR1_RS03220 WP_004197422.1 612363..613364(+) (ccpA) [Streptococcus thermophilus strain R1]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=510535 STR1_RS03220 WP_004197422.1 612363..613364(+) (ccpA) [Streptococcus thermophilus strain R1]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547