Detailed information NTG0510232

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: ST90730_RS01495
• Genome accession: NZ_CP065481
• Coordinates: 269931..270830 (+)
• Length: 299 a.a.
• NCBI ID: WP_011226854.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain 90730
• Function: activate transcription of comX; activate transcription of comS (predicted from homology) Competence regulation

Genomic Context

Location: 264931..275830

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90730_RS01475 (ST90730_01455)	trkA	266067..267416 (-)	1350	WP_011225444.1	Trk system potassium transporter TrkA	-
ST90730_RS01480 (ST90730_01460)	-	267705..268214 (+)	510	WP_011680717.1	tRNA (cytidine(34)-2'-O)-methyltransferase	-
ST90730_RS01485 (ST90730_01465)	-	268526..269083 (+)	558	WP_002949523.1	ECF transporter S component	-
ST90730_RS01490 (ST90730_01470)	-	269086..269736 (+)	651	WP_011226853.1	phosphatase PAP2 family protein	-
ST90730_RS01495 (ST90730_01475)	comR	269931..270830 (+)	900	WP_011226854.1	helix-turn-helix domain-containing protein	Regulator
ST90730_RS01500	-	271069..272247 (+)	1179	Protein_242	ABC transporter transmembrane domain-containing protein	-
ST90730_RS01505 (ST90730_01500)	-	272533..273101 (+)	569	Protein_243	ATP-binding cassette domain-containing protein	-
ST90730_RS01510 (ST90730_01505)	-	273209..273520 (+)	312	WP_011226857.1	DUF805 domain-containing protein	-
ST90730_RS01515	-	273488..273772 (-)	285	WP_231108755.1	hypothetical protein	-
ST90730_RS01520	-	274012..274314 (-)	303	WP_011226859.1	hypothetical protein	-
ST90730_RS01525	-	274538..274909 (-)	372	WP_231108754.1	hypothetical protein	-
ST90730_RS01530 (ST90730_01515)	-	275314..275829 (+)	516	WP_011226861.1	AmiS/UreI family transporter	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35317.79 Da
• Isoelectric Point: 5.1073

>NTDB_id=510232 ST90730_RS01495 WP_011226854.1 269931..270830(+) (comR) [Streptococcus thermophilus strain 90730]
MNIKDSIGLRIKTERERQQMSREVLCLDGAELTVRQLIRIEKGESLPSLDRLSYIAKRLGKSMTELLDQDNITIPDEYYE
MKNRLIKFPTYRNPDRIKSKLTLIEEVYEKFFDILPEEELLTLDILENILSFTSWEESPKVEEIYEDLFEQVKRKRKFST
NDLLIIDYYFFHLYGRKQYDKKLFERIIKRVLNQEIWTDDVYNIVLFNDLMAIAALKIFHNSFSDFLTVVDKALAVIEKS
QLYSYKPSVFVLKAKYELLHKENKKEAAENYDKAIMFASVLEDSVLEESIKAGKLADGL

Nucleotide

• Length: 900 bp

>NTDB_id=510232 ST90730_RS01495 WP_011226854.1 269931..270830(+) (comR) [Streptococcus thermophilus strain 90730]
TTGAACATAAAAGACAGCATTGGACTAAGAATCAAAACTGAGCGTGAACGCCAACAGATGTCACGTGAAGTGCTATGTTT
AGATGGTGCGGAATTGACTGTTCGCCAGTTAATTCGTATTGAAAAGGGGGAGTCTCTCCCGTCTTTAGATAGATTATCGT
ATATTGCTAAACGTTTAGGAAAAAGTATGACAGAGTTATTGGATCAAGACAATATTACCATTCCTGACGAATATTATGAA
ATGAAGAATCGTTTGATTAAGTTTCCAACGTACAGAAACCCTGACAGAATAAAGTCTAAACTTACTTTGATTGAGGAAGT
CTATGAGAAATTTTTTGATATTCTTCCAGAAGAAGAATTATTAACTCTAGACATTCTCGAAAATATATTGAGTTTTACTA
GCTGGGAGGAGAGTCCAAAAGTTGAGGAGATATATGAAGACTTGTTTGAACAAGTCAAAAGGAAGAGGAAATTCTCAACT
AACGATTTATTAATCATTGACTATTATTTCTTTCATCTTTATGGGAGAAAACAGTATGACAAAAAACTATTTGAAAGAAT
TATAAAGAGAGTATTAAATCAGGAAATTTGGACAGATGATGTTTACAATATTGTTTTATTTAATGATTTGATGGCTATTG
CTGCTTTAAAGATTTTTCACAATTCCTTCTCAGACTTCTTAACAGTTGTGGATAAAGCCTTAGCTGTCATAGAAAAATCA
CAATTATATAGCTACAAGCCTAGTGTTTTTGTACTTAAGGCTAAATATGAACTTCTGCATAAAGAAAACAAGAAAGAGGC
TGCAGAGAATTATGATAAGGCCATAATGTTTGCTTCCGTTTTGGAAGACTCGGTTTTAGAGGAAAGTATAAAGGCAGGAA
AATTGGCAGATGGTTTATAG

Domains

Predicted by InterproScan.

• Helix-turn-helix (HTH_3) (11-66)

• ComR tetratricopeptide (ComR_TPR) (75-292)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus thermophilus LMG 18311	99.666	100	0.997
comR	Streptococcus thermophilus LMD-9	98.997	100	0.99
comR	Streptococcus salivarius strain HSISS4	94.983	100	0.95
comR	Streptococcus salivarius SK126	94.314	100	0.943
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	42.14	100	0.421