Detailed information NTG0510121

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST90728_RS03170
• Genome accession: NZ_CP065479
• Coordinates: 584234..585235 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 90728
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 579234..590235

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST90728_RS03150 (ST90728_03160)	smpB	580339..580803 (+)	465	WP_347114434.1	SsrA-binding protein SmpB	-
ST90728_RS03155 (ST90728_03165)	-	580957..582363 (+)	1407	WP_002950242.1	Cof-type HAD-IIB family hydrolase	-
ST90728_RS03160 (ST90728_03170)	-	582365..582730 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST90728_RS03165 (ST90728_03175)	-	582833..583918 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
ST90728_RS03170 (ST90728_03180)	ccpA	584234..585235 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST90728_RS03175 (ST90728_03185)	-	585294..585491 (+)	198	WP_014608125.1	hypothetical protein	-
ST90728_RS03180 (ST90728_03190)	-	585597..586169 (+)	573	WP_347114435.1	MmcQ/YjbR family DNA-binding protein	-
ST90728_RS03185 (ST90728_03195)	-	586377..587492 (+)	1116	WP_002950249.1	glycerate kinase	-
ST90728_RS03190 (ST90728_03200)	-	587531..587986 (-)	456	WP_087009787.1	YueI family protein	-
ST90728_RS03195 (ST90728_03205)	eno	588194..589498 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
ST90728_RS03200 (ST90728_03210)	-	589651..589835 (-)	185	Protein_568	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=510121 ST90728_RS03170 WP_004197422.1 584234..585235(+) (ccpA) [Streptococcus thermophilus strain 90728]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=510121 ST90728_RS03170 WP_004197422.1 584234..585235(+) (ccpA) [Streptococcus thermophilus strain 90728]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCGAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCTGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547