Detailed information NTG0510003

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST4078_RS03325
• Genome accession: NZ_CP065477
• Coordinates: 612102..613103 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 4078
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 607102..618103

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4078_RS03305 (ST4078_03255)	smpB	608209..608673 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST4078_RS03310 (ST4078_03260)	-	608827..610233 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
ST4078_RS03315 (ST4078_03265)	-	610235..610600 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST4078_RS03320 (ST4078_03270)	-	610703..611788 (-)	1086	WP_011680935.1	M24 family metallopeptidase	-
ST4078_RS03325 (ST4078_03275)	ccpA	612102..613103 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST4078_RS03330 (ST4078_03280)	-	613162..613359 (+)	198	WP_014608125.1	hypothetical protein	-
ST4078_RS03335	-	613465..613689 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
ST4078_RS03340 (ST4078_03285)	-	613690..614229 (+)	540	WP_011680936.1	MmcQ/YjbR family DNA-binding protein	-
ST4078_RS03345 (ST4078_03290)	-	614242..615357 (+)	1116	WP_011680937.1	glycerate kinase	-
ST4078_RS03350 (ST4078_03295)	-	615404..615859 (-)	456	WP_011680938.1	YueI family protein	-
ST4078_RS03355 (ST4078_03300)	eno	616068..617372 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-
ST4078_RS03360 (ST4078_03305)	-	617524..617709 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=510003 ST4078_RS03325 WP_004197422.1 612102..613103(+) (ccpA) [Streptococcus thermophilus strain 4078]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=510003 ST4078_RS03325 WP_004197422.1 612102..613103(+) (ccpA) [Streptococcus thermophilus strain 4078]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547