Detailed information NTG0509945

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST4052_RS03200
• Genome accession: NZ_CP065476
• Coordinates: 594368..595369 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 4052
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 589368..600369

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST4052_RS03180 (ST4052_03185)	smpB	590474..590938 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST4052_RS03185 (ST4052_03190)	-	591092..592498 (+)	1407	WP_011227013.1	Cof-type HAD-IIB family hydrolase	-
ST4052_RS03190 (ST4052_03195)	-	592500..592865 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST4052_RS03195 (ST4052_03200)	-	592968..594053 (-)	1086	WP_011225703.1	Xaa-Pro peptidase family protein	-
ST4052_RS03200 (ST4052_03205)	ccpA	594368..595369 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST4052_RS03205 (ST4052_03210)	-	595428..595625 (+)	198	WP_011225705.1	hypothetical protein	-
ST4052_RS03210 (ST4052_03215)	-	595731..596495 (+)	765	WP_347100919.1	MmcQ/YjbR family DNA-binding protein	-
ST4052_RS03215 (ST4052_03220)	-	596510..597625 (+)	1116	WP_011227015.1	glycerate kinase	-
ST4052_RS03220 (ST4052_03225)	-	597664..598119 (-)	456	WP_002950250.1	YueI family protein	-
ST4052_RS03225 (ST4052_03230)	eno	598328..599632 (+)	1305	WP_011225708.1	surface-displayed alpha-enolase	-
ST4052_RS03230 (ST4052_03235)	-	599784..599968 (-)	185	Protein_574	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=509945 ST4052_RS03200 WP_004197422.1 594368..595369(+) (ccpA) [Streptococcus thermophilus strain 4052]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=509945 ST4052_RS03200 WP_004197422.1 594368..595369(+) (ccpA) [Streptococcus thermophilus strain 4052]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCTGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547