Detailed information NTG0509609

Bioinformatically predicted

Overview

• Name: comA/comEC
• Type: Machinery gene
• Locus tag: I5593_RS04225
• Genome accession: NZ_CP065432
• Coordinates: 906092..908524 (+)
• Length: 810 a.a.
• NCBI ID: WP_000472725.1
• Uniprot ID: A0A6F8TDY5
• Organism: Acinetobacter baumannii strain ATCC 17961
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Prophage	901063..913201	906092..908524	within	0

Gene organization within MGE regions

Location: 901063..913201

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I5593_RS04195 (I5593_04195)	-	901063..901209 (-)	147	WP_000691794.1	hypothetical protein	-
I5593_RS04200 (I5593_04200)	-	901243..902184 (-)	942	WP_000795874.1	hypothetical protein	-
I5593_RS04205 (I5593_04205)	-	902441..902926 (+)	486	WP_001985538.1	YaiI/YqxD family protein	-
I5593_RS04210 (I5593_04210)	-	902937..903845 (+)	909	WP_001140081.1	DMT family transporter	-
I5593_RS19545	-	903875..903955 (-)	81	Protein_801	PilZ domain-containing protein	-
I5593_RS04215 (I5593_04215)	-	904093..905328 (+)	1236	WP_001984636.1	lipoprotein-releasing ABC transporter permease subunit	-
I5593_RS04220 (I5593_04220)	lolD	905321..906007 (+)	687	WP_000049406.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
I5593_RS04225 (I5593_04225)	comA/comEC	906092..908524 (+)	2433	WP_000472725.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
I5593_RS04230 (I5593_04230)	-	908477..909460 (-)	984	WP_001984639.1	lysophospholipid acyltransferase family protein	-
I5593_RS04235 (I5593_04235)	sppA	909597..910613 (+)	1017	WP_001286607.1	signal peptide peptidase SppA	-
I5593_RS04240 (I5593_04240)	-	910632..911441 (+)	810	WP_000114071.1	alpha/beta fold hydrolase	-
I5593_RS04245 (I5593_04245)	purN	911505..912134 (-)	630	WP_000975526.1	phosphoribosylglycinamide formyltransferase	-
I5593_RS04250 (I5593_04250)	purM	912131..913201 (-)	1071	WP_000071984.1	phosphoribosylformylglycinamidine cyclo-ligase	-

Sequence

Protein

• Length: 810 a.a.
• Molecular weight: 92398.75 Da
• Isoelectric Point: 8.7619

>NTDB_id=509609 I5593_RS04225 WP_000472725.1 906092..908524(+) (comA/comEC) [Acinetobacter baumannii strain ATCC 17961]
MFKIILLGWIGGIALMGIDFPLIMQYEKVGKALLLLAFIFYLYKRPMFGDRPFLKAVFCLLCTTSLFMVGYHYAEKALIE
RLEQRETDTRNLDIIVYINRLSEEKDNKVQQTAQVLNLSKEPVNWLLYLKSNNQNLLKNNQNLELGHYYRISGKTRPAHS
YATPGAFDQEKWFIQRNIMSGFNVRYIEPLSLDEIYRLGYQQHLKEQQSFSNSFRLNIEKLRLTFRQILNSSSLQQKGLI
LALLTGDESLLSDETQLQFKQLGISHLLAISGPHVLIFAIMLSWACHQFISRYYPQIYLWKPKQVLMAVPCCLGVLIYTA
FVGFEIPALRTLLSAFIFIGFLLLKQPIKPFTLLVYSASLLLLMDPFSVLSAGFWLSYGACFILLRIYQTIAQLPEQHFL
SLSSKMIFMSKVLIESQGKIFIALSPLTLLFFQQISWVAPLTNIIAVPIVGGVIVPLNIMAACAWFVIKPFGNMLFHFND
MLLSILLSCLGLLEKLSLPLQGISLTPLSLLAISCAIIILFLPKGILPKTWGILCCLPLVIMNKTSQQIQLNILDVGQGQ
AIFLQHPEQNWLIDTGGSYDEKIFSIGQNVVVPFLRQQGVRQLDHVVLSHLDQDHSGAFPLIQQEIPVKQLISNEQLPND
LKQPFQYCYQGQQWHYPELDIQILWPKEKDLAFVASNQNQYSCVVYLQFKKVGGYQNFLIMGDAGWEAEYELLKDYPNLK
IDVLVLGHHGSKHSSAYDFLATLKPKLAIASAGFDNRYGHPSQQVIARLKALHIPLKSTVEQGTLSFVLENHKIVLHDRR
LDRLWLSRGF

Nucleotide

• Length: 2433 bp

>NTDB_id=509609 I5593_RS04225 WP_000472725.1 906092..908524(+) (comA/comEC) [Acinetobacter baumannii strain ATCC 17961]
ATGTTTAAGATTATTCTATTGGGGTGGATTGGCGGTATTGCATTGATGGGAATAGATTTCCCTTTAATCATGCAATATGA
AAAAGTGGGCAAGGCTCTACTGTTACTTGCCTTTATTTTTTATCTTTATAAACGCCCCATGTTCGGTGATCGACCATTTT
TAAAGGCAGTGTTTTGCTTATTATGTACAACAAGTCTTTTTATGGTTGGTTACCACTATGCTGAAAAAGCACTGATTGAA
CGATTAGAACAAAGAGAAACAGATACCCGAAATCTCGACATTATTGTTTATATAAACCGTTTAAGTGAAGAAAAAGATAA
TAAGGTTCAACAAACTGCACAAGTTCTAAATCTTTCTAAAGAACCGGTGAATTGGTTGCTATATTTAAAAAGTAATAATC
AAAATTTATTAAAGAATAATCAGAATCTTGAATTAGGTCACTATTATCGAATATCTGGAAAAACAAGACCTGCGCATAGT
TATGCCACCCCAGGAGCTTTTGATCAGGAAAAGTGGTTTATTCAGCGAAATATTATGTCTGGTTTTAACGTGAGATATAT
TGAGCCTTTAAGCCTTGATGAAATCTATCGATTAGGCTATCAGCAACATTTAAAAGAACAACAGTCTTTTTCCAATAGTT
TTCGTTTAAATATAGAAAAACTTCGCTTAACTTTTAGGCAAATATTAAACAGCTCATCTTTACAGCAAAAGGGTTTAATT
TTAGCTTTGCTGACAGGTGATGAAAGTCTTTTATCAGATGAAACTCAACTACAGTTCAAACAATTAGGAATTAGTCATTT
ATTGGCGATCTCAGGCCCACATGTGCTCATTTTTGCCATTATGTTATCTTGGGCATGTCATCAATTTATTAGTCGTTATT
ATCCTCAAATTTATTTATGGAAACCGAAACAGGTTTTGATGGCTGTACCATGCTGCCTTGGTGTTTTAATTTATACTGCA
TTTGTAGGTTTCGAAATTCCTGCACTACGAACATTATTATCAGCATTTATATTTATTGGTTTTCTATTATTAAAACAACC
TATTAAACCTTTTACATTACTCGTATATAGTGCAAGTCTACTGTTGCTAATGGACCCGTTTAGTGTGCTTTCTGCAGGTT
TTTGGCTGTCTTATGGGGCATGTTTTATTTTATTAAGAATTTACCAAACTATAGCGCAGCTACCTGAGCAACATTTTTTG
AGTCTGAGTTCAAAAATGATTTTTATGAGTAAGGTGTTAATTGAATCTCAAGGCAAAATATTTATTGCATTGAGTCCTTT
AACCTTACTTTTCTTTCAACAAATTTCTTGGGTTGCTCCATTAACCAATATTATTGCCGTGCCTATTGTTGGGGGTGTTA
TTGTCCCTTTAAACATCATGGCTGCTTGCGCATGGTTTGTAATAAAACCATTTGGAAATATGCTTTTTCATTTCAATGAT
ATGTTGCTCAGCATATTGCTGAGTTGTTTGGGCTTATTAGAAAAACTCTCTTTACCATTACAAGGTATAAGCTTGACGCC
ACTGTCTTTATTAGCGATTAGTTGTGCCATTATTATTTTATTTTTACCTAAAGGAATTCTGCCCAAAACTTGGGGAATAT
TATGTTGTTTACCCTTAGTTATTATGAACAAAACGAGTCAGCAAATTCAGCTTAATATTTTAGATGTTGGGCAGGGGCAG
GCTATTTTTCTACAACATCCCGAACAAAACTGGTTAATTGACACAGGCGGTTCTTACGATGAAAAAATATTTAGTATTGG
ACAAAATGTTGTAGTGCCTTTTCTACGTCAGCAAGGCGTAAGACAACTAGATCATGTTGTGCTATCCCATCTTGATCAAG
ACCATAGTGGCGCGTTTCCTCTTATTCAACAAGAGATTCCTGTAAAGCAGCTTATTTCGAATGAACAATTACCAAATGAT
TTAAAGCAACCATTCCAATATTGCTATCAAGGGCAACAATGGCATTATCCTGAGTTAGATATTCAAATTTTATGGCCTAA
AGAAAAAGATCTGGCTTTTGTTGCTTCTAATCAGAATCAATATTCTTGTGTTGTATATCTTCAATTTAAAAAAGTTGGTG
GTTACCAAAATTTTCTTATTATGGGCGATGCTGGATGGGAAGCTGAATACGAGTTATTAAAAGATTATCCTAACTTGAAG
ATAGATGTGTTGGTGCTAGGGCATCATGGAAGTAAGCACAGTTCGGCTTATGATTTCTTGGCGACCTTAAAACCTAAACT
GGCCATTGCATCGGCAGGGTTTGATAACCGTTATGGCCATCCTAGCCAACAAGTTATAGCACGTTTAAAAGCTCTACATA
TTCCGCTAAAAAGCACTGTGGAACAAGGAACCTTAAGTTTTGTGTTGGAAAACCACAAAATAGTTTTACATGACCGACGT
TTGGATAGGCTCTGGTTGAGTAGAGGTTTTTAA

Domains

Predicted by InterproScan.

• Competence protein (Competence) (243-521)

• Domain of unknown function (DUF4131) (DUF4131) (33-188)

• Metallo-beta-lactamase superfamily (Lactamase_B) (555-645)

3D structure

• AlphaFold DB: A0A6F8TDY5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/comEC	Acinetobacter baumannii D1279779	98.642	100	0.986
comA/comEC	Acinetobacter baumannii strain A118	97.407	100	0.974
comA/comEC	Acinetobacter baylyi ADP1	50.308	100	0.504