Detailed information NTG0509085

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: ST1A_RS03300
• Genome accession: NZ_CP065384
• Coordinates: 616461..617462 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 1A
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 611461..622462

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ST1A_RS03280 (ST1A_03240)	smpB	612564..613028 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
ST1A_RS03285 (ST1A_03245)	-	613182..614588 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
ST1A_RS03290 (ST1A_03250)	-	614590..614955 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
ST1A_RS03295 (ST1A_03255)	-	615058..616143 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
ST1A_RS03300 (ST1A_03260)	ccpA	616461..617462 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
ST1A_RS03305 (ST1A_03265)	-	617521..617718 (+)	198	WP_014608125.1	hypothetical protein	-
ST1A_RS03310	-	617824..618048 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
ST1A_RS03315 (ST1A_03270)	-	618049..618588 (+)	540	WP_011680936.1	hypothetical protein	-
ST1A_RS03320 (ST1A_03275)	-	618601..619716 (+)	1116	WP_011680937.1	glycerate kinase	-
ST1A_RS03325 (ST1A_03280)	-	619763..620218 (-)	456	WP_011680938.1	YueI family protein	-
ST1A_RS03330 (ST1A_03285)	eno	620427..621731 (+)	1305	WP_011680939.1	surface-displayed alpha-enolase	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=509085 ST1A_RS03300 WP_004197422.1 616461..617462(+) (ccpA) [Streptococcus thermophilus strain 1A]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=509085 ST1A_RS03300 WP_004197422.1 616461..617462(+) (ccpA) [Streptococcus thermophilus strain 1A]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547