Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   I2439_RS05065 Genome accession   NZ_CP065191
Coordinates   1058030..1059340 (+) Length   436 a.a.
NCBI ID   WP_111678059.1    Uniprot ID   A0AAX2LI37
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ46     
Function   Required for optimal comC expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1053030..1064340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2439_RS05050 (HIEAAJJG_01019) phoU 1053511..1054164 (+) 654 WP_012678018.1 phosphate signaling complex protein PhoU -
  I2439_RS05055 (HIEAAJJG_01020) - 1054399..1056936 (+) 2538 WP_196820065.1 M1 family metallopeptidase -
  I2439_RS05060 (HIEAAJJG_01021) ciaR 1057363..1058037 (+) 675 WP_111678058.1 response regulator transcription factor Regulator
  I2439_RS05065 (HIEAAJJG_01022) ciaH 1058030..1059340 (+) 1311 WP_111678059.1 HAMP domain-containing sensor histidine kinase Regulator
  I2439_RS05070 (HIEAAJJG_01023) - 1059725..1060069 (+) 345 WP_243272241.1 hypothetical protein -
  I2439_RS05075 (HIEAAJJG_01025) - 1060381..1060764 (+) 384 WP_037579880.1 hypothetical protein -
  I2439_RS05080 (HIEAAJJG_01026) - 1060775..1061020 (+) 246 WP_196820066.1 hypothetical protein -
  I2439_RS05085 (HIEAAJJG_01027) - 1061195..1061575 (+) 381 WP_042670594.1 hypothetical protein -
  I2439_RS05090 (HIEAAJJG_01028) - 1061572..1062780 (+) 1209 WP_196820067.1 hypothetical protein -
  I2439_RS05095 (HIEAAJJG_01029) - 1062777..1063169 (+) 393 WP_165627640.1 hypothetical protein -
  I2439_RS05100 (HIEAAJJG_01030) - 1063190..1063474 (+) 285 WP_037579874.1 hypothetical protein -
  I2439_RS05105 (HIEAAJJG_01031) rpsT 1063687..1063920 (-) 234 WP_037578328.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 436 a.a.        Molecular weight: 49660.31 Da        Isoelectric Point: 9.5548

>NTDB_id=507826 I2439_RS05065 WP_111678059.1 1058030..1059340(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
MNKLKKELLSDNYTHFFHFFAIFTGIFVVMTIIILQIMRFSVYSTVDSSLISVGQNASNYANRTMARISSFYFDAENNLI
QALPELEASKSLGSSTTNMDIILFSANGTILNSFDAFSNYQSFRLDKSQLNNIVTTQLMNFYGQKEKYHTLTVKVHIKNY
PAVAYMMAVVNVQQLDTANERYEQIIIMVMIVFWLISILASIYLAKWSRKPIMESYAKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHIASSLDEVRNMRILTTNLLNLARRDDGIKPQLVDVDAAFFDTVFENYQLVAEESGKQFISAN
QINRPLKTDKALLKQLMTILFDNAIKYTDHNGVVEVKVRTTDKHLLISVIDNGPGIKDDDKKKIFDRFYRVDKARTRQKG
GFGLGLALAQQIVTSLKGTITVSDNKPTGAIFEVKL

Nucleotide


Download         Length: 1311 bp        

>NTDB_id=507826 I2439_RS05065 WP_111678059.1 1058030..1059340(+) (ciaH) [Streptococcus equi subsp. zooepidemicus strain SEZ46]
ATGAATAAACTAAAAAAAGAATTATTGTCCGATAATTATACACATTTTTTTCATTTCTTTGCTATTTTTACAGGCATTTT
TGTTGTCATGACTATCATTATTTTGCAAATCATGAGGTTTAGTGTCTATTCCACAGTAGACAGCAGTCTCATTTCGGTCG
GTCAAAATGCCAGCAACTATGCCAATAGGACCATGGCGAGAATATCTTCCTTTTATTTTGATGCAGAAAATAACCTTATT
CAGGCTCTTCCTGAATTGGAAGCGTCAAAATCACTTGGCTCCTCCACCACTAATATGGATATTATTTTATTTAGTGCCAA
TGGGACGATATTGAATTCCTTTGACGCCTTCTCCAATTACCAAAGCTTTCGTTTAGACAAAAGTCAGCTTAATAACATTG
TCACAACACAGCTGATGAATTTTTATGGGCAAAAGGAGAAATACCATACCCTAACCGTTAAGGTCCACATTAAAAACTAT
CCGGCAGTGGCTTATATGATGGCAGTGGTTAATGTTCAGCAACTGGATACTGCCAATGAGCGCTATGAACAGATTATTAT
CATGGTTATGATTGTCTTTTGGTTAATTTCGATTTTAGCCAGCATTTATTTAGCGAAGTGGAGCAGAAAGCCAATTATGG
AGAGCTATGCCAAGCAAAAAATGTTTGTAGAAAATGCCAGTCATGAGCTTAGAACTCCTTTGGCTGTGCTGCAAAATCGT
TTGGAATCACTGTTTAGAAAGCCTAACGAGACCATTTTAGAAAATAGTGAGCATATTGCTTCAAGCCTAGATGAGGTCCG
CAATATGAGAATATTAACCACTAATTTGTTGAATTTAGCTAGACGCGATGATGGGATCAAGCCGCAGCTAGTTGATGTTG
ATGCAGCCTTTTTTGATACTGTTTTTGAAAATTATCAATTAGTTGCAGAAGAATCAGGCAAGCAGTTTATCTCAGCCAAT
CAGATCAATAGGCCCTTAAAGACGGATAAGGCTTTGCTCAAGCAGCTGATGACCATTTTGTTTGATAATGCGATCAAATA
CACTGATCATAACGGTGTGGTTGAGGTCAAGGTTAGAACGACCGATAAGCATTTATTGATTTCTGTTATTGATAATGGCC
CAGGGATCAAGGATGATGATAAGAAAAAGATTTTTGATCGCTTTTACCGAGTGGATAAGGCAAGGACACGCCAAAAAGGA
GGCTTTGGACTCGGATTGGCCTTAGCGCAGCAGATCGTTACCTCATTAAAAGGAACGATTACCGTCAGCGATAATAAGCC
TACCGGCGCTATTTTTGAGGTAAAATTATAG

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(220-285)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(329-436)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus mutans UA159

57.666

100

0.578
  ciaH Streptococcus pneumoniae Rx1

51.147

100

0.511
  ciaH Streptococcus pneumoniae D39

51.147

100

0.511
  ciaH Streptococcus pneumoniae R6

51.147

100

0.511
  ciaH Streptococcus pneumoniae TIGR4

51.147

100

0.511