Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   I2438_RS07915 Genome accession   NZ_CP065190
Coordinates   1632422..1633171 (-) Length   249 a.a.
NCBI ID   WP_024273220.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1627422..1638171
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS07900 (HCFMJIKG_01570) - 1629377..1630735 (+) 1359 WP_021321060.1 bacteriocin secretion accessory protein -
  I2438_RS07905 (HCFMJIKG_01571) - 1630835..1630969 (+) 135 WP_012516117.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  I2438_RS10540 (HCFMJIKG_01572) - 1631088..1632422 (-) 1335 WP_021321061.1 sensor histidine kinase -
  I2438_RS07915 (HCFMJIKG_01573) comE/blpR 1632422..1633171 (-) 750 WP_024273220.1 LytR/AlgR family response regulator transcription factor Regulator
  I2438_RS07920 (HCFMJIKG_01574) - 1633798..1634001 (-) 204 WP_012516120.1 TmhB bacteriocin enhancer peptide -
  I2438_RS07925 (HCFMJIKG_01575) - 1634018..1634275 (-) 258 WP_012516121.1 Blp family class II bacteriocin -
  I2438_RS07930 (HCFMJIKG_01576) rlmD 1634596..1635963 (-) 1368 WP_012516122.1 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD -
  I2438_RS07935 (HCFMJIKG_01577) - 1635960..1636928 (-) 969 WP_012516123.1 helix-hairpin-helix domain-containing protein -
  I2438_RS07940 (HCFMJIKG_01578) prx 1637068..1637250 (-) 183 WP_206156615.1 Paratox Regulator

Sequence

Protein


Download         Length: 249 a.a.        Molecular weight: 29193.69 Da        Isoelectric Point: 8.3306

>NTDB_id=507778 I2438_RS07915 WP_024273220.1 1632422..1633171(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MRVVILEDDMIQQRCLEKLIKELEVKHQLLFQGLDCFGRPHQLLSAIKKNCGQQLFFLDIEIKNEDKKGLEVARQIRQIN
PDAMIVFVTTHSEFMPLAFQYQVSALDYIDKELPHTEFVQRVETALLYAVRQNSETIAESAFYFTSRYAQVQVPFNDILY
IETSSRAHRVNLYTKKERMQFTGTLTDILKQESRFLQCHRSFLINPRNVVRVDKIERVVYFRNGSSCLIARSKMNSVLTT
IENLYRGDN

Nucleotide


Download         Length: 750 bp        

>NTDB_id=507778 I2438_RS07915 WP_024273220.1 1632422..1633171(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
GTGAGAGTAGTTATTTTAGAAGATGATATGATTCAACAGAGATGTTTAGAAAAGCTTATTAAAGAGCTTGAGGTTAAGCA
CCAGCTATTATTTCAAGGACTTGATTGTTTTGGAAGGCCTCACCAGCTATTAAGTGCTATTAAGAAGAACTGTGGTCAGC
AGCTATTCTTTTTAGATATTGAGATAAAAAATGAGGACAAAAAAGGGCTTGAGGTTGCTAGGCAAATTCGTCAGATAAAT
CCAGATGCGATGATTGTTTTTGTAACGACTCACTCGGAATTTATGCCCTTGGCTTTTCAGTATCAGGTATCTGCTTTGGA
CTATATCGATAAAGAGCTGCCTCACACTGAGTTTGTTCAACGGGTAGAGACTGCTTTATTATATGCTGTGCGGCAAAATA
GTGAAACGATAGCGGAAAGTGCTTTTTATTTTACATCTCGTTATGCTCAGGTACAGGTGCCTTTTAATGATATCCTGTAT
ATTGAGACATCGTCACGAGCGCATCGTGTCAATTTGTATACAAAAAAGGAGAGAATGCAATTTACAGGGACTTTGACGGA
TATTTTGAAGCAAGAGTCTCGTTTTTTGCAATGTCATCGTTCTTTTTTGATTAATCCTAGGAATGTCGTTAGGGTAGATA
AGATTGAGCGAGTGGTTTATTTTCGAAATGGCTCTAGCTGCTTAATTGCTCGTAGTAAAATGAACAGTGTTTTAACAACA
ATTGAGAACCTATATAGAGGAGATAATTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-237)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.61

100

0.526
  comE/comE1 Streptococcus equinus JB1

40.167

95.984

0.386