Detailed information    

insolico Bioinformatically predicted

Overview

Name   vicK   Type   Regulator
Locus tag   I2438_RS07295 Genome accession   NZ_CP065190
Coordinates   1496206..1497558 (-) Length   450 a.a.
NCBI ID   WP_012677636.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ36     
Function   repress comCDE expression; repress comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1491206..1502558
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2438_RS07280 (HCFMJIKG_01444) rnc 1492048..1492740 (-) 693 WP_037581642.1 ribonuclease III -
  I2438_RS07285 (HCFMJIKG_01445) - 1492999..1494513 (-) 1515 WP_021320991.1 helix-turn-helix domain-containing protein -
  I2438_RS07290 (HCFMJIKG_01446) vicX 1495393..1496202 (-) 810 WP_021320992.1 MBL fold metallo-hydrolase Regulator
  I2438_RS07295 (HCFMJIKG_01447) vicK 1496206..1497558 (-) 1353 WP_012677636.1 cell wall metabolism sensor histidine kinase VicK Regulator
  I2438_RS07300 (HCFMJIKG_01448) vicR 1497551..1498261 (-) 711 WP_012515994.1 response regulator YycF Regulator
  I2438_RS07305 (HCFMJIKG_01449) - 1498470..1499486 (-) 1017 WP_014623189.1 DUF3114 domain-containing protein -
  I2438_RS07310 (HCFMJIKG_01450) - 1499532..1500794 (-) 1263 WP_014623190.1 AMP-binding protein -
  I2438_RS07315 (HCFMJIKG_01451) - 1500784..1501899 (-) 1116 WP_024273213.1 acetyl-CoA C-acyltransferase -
  I2438_RS07320 (HCFMJIKG_01452) - 1501896..1502435 (-) 540 WP_021320995.1 hypothetical protein -

Sequence

Protein


Download         Length: 450 a.a.        Molecular weight: 51541.94 Da        Isoelectric Point: 5.5557

>NTDB_id=507773 I2438_RS07295 WP_012677636.1 1496206..1497558(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MTKDIIGNLSAFELAILLLLVFVAFYFIHLAIRDYRNARIIRLMSHKIRDLINGRYTDTINEKADIELMELSEQLNDLSD
VFRLTHENLAQEKNRLASILAYMTDGVLATNRSGKIIMINETAQKQLNLNREQALEKNITDLLDSDSPYTYRELVSKTPI
VTLNRRNDTGEFVSLRLRFALNRRESGFISGLVVVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALK
EDIAPSFIKVSLDETNRMMRMISDLLNLSRIDNHVTQLSVEMTNFTAFMTSILNRFDLVKNQHTSTGKSYEIVRDYPITS
IWLEIDNDKMTQVIENILNNAIKYSPDGGKIIVNMKTTDTQLIISISDEGLGIPKKDLPLIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHRGFIWAKSDYGKGSTFTIVLPYEKDAAIYDEWEDDID

Nucleotide


Download         Length: 1353 bp        

>NTDB_id=507773 I2438_RS07295 WP_012677636.1 1496206..1497558(-) (vicK) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGACTAAGGACATCATTGGAAACCTTTCTGCATTTGAGCTAGCCATACTCTTATTGCTTGTTTTTGTTGCTTTTTATTT
CATTCATTTAGCCATTCGTGATTATCGCAATGCTCGGATCATTCGTCTGATGAGCCACAAGATAAGAGATTTGATCAATG
GTCGCTATACTGATACGATCAATGAAAAGGCTGATATTGAATTGATGGAGCTGTCTGAGCAGCTCAATGACCTATCAGAT
GTTTTTCGTCTGACTCATGAAAACCTTGCTCAAGAAAAAAATCGTCTTGCTAGTATTTTGGCTTATATGACAGATGGGGT
CCTTGCGACCAATCGTTCCGGCAAGATTATCATGATTAATGAGACTGCTCAAAAGCAGCTCAATTTAAATCGCGAGCAGG
CCTTGGAAAAAAACATTACAGATTTATTAGACAGTGACTCCCCTTATACCTACCGAGAGCTGGTCTCAAAAACACCGATT
GTGACCTTAAACCGTCGTAATGATACAGGAGAATTTGTTTCCCTGCGGCTGCGCTTTGCGCTTAATAGGCGAGAGAGCGG
CTTTATTTCAGGTCTGGTTGTTGTGCTTCATGACACGACTGAGCAGGAAAAGGAAGAGCGTGAGCGCAGACTCTTTGTTT
CAAATGTTAGCCATGAGCTGCGGACACCTTTGACCTCTGTCAAGTCATACCTAGAGGCTCTAGATGAGGGCGCGCTAAAG
GAGGACATCGCTCCAAGCTTTATAAAGGTCTCACTAGATGAAACCAATCGCATGATGCGCATGATTTCAGATTTGCTCAA
TCTATCAAGAATTGATAATCATGTGACACAGCTGTCTGTTGAAATGACCAACTTTACAGCCTTTATGACCTCTATCTTAA
ACCGCTTTGATTTGGTGAAAAATCAGCACACCAGTACAGGAAAATCCTATGAAATTGTCAGAGATTACCCTATCACCTCT
ATTTGGCTAGAAATTGATAACGATAAAATGACGCAGGTCATTGAAAATATTTTAAACAATGCCATCAAATATTCACCTGA
TGGTGGGAAAATTATCGTAAACATGAAAACAACAGATACCCAGCTAATCATTTCGATTTCTGATGAGGGTTTGGGCATTC
CAAAAAAGGACCTGCCTTTGATTTTTGACCGTTTTTACCGAGTGGATAAGGCTAGAAGTCGGGCGCAGGGGGGTACCGGC
TTAGGGCTGGCTATTGCCAAAGAAATTATCAAGCAGCACCGAGGCTTTATCTGGGCTAAGAGTGACTATGGTAAGGGGTC
AACCTTTACCATTGTGTTACCTTACGAAAAGGATGCTGCTATCTATGATGAATGGGAGGATGATATTGATTAA

Domains

Predicted by InterproScan.

PAS fold (PAS)

(95-197)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(326-436)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vicK Streptococcus mutans UA159

73.671

92

0.678
  micB Streptococcus pneumoniae Cp1015

66.824

94.444

0.631