Detailed information NTG0507766

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I2438_RS05305
• Genome accession: NZ_CP065190
• Coordinates: 1074668..1075405 (+)
• Length: 245 a.a.
• NCBI ID: WP_021320758.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ36
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	1075473..1077043	1074668..1075405	flank	68

Gene organization within MGE regions

Location: 1074668..1077043

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2438_RS05305 (HCFMJIKG_01047)	comE/blpR	1074668..1075405 (+)	738	WP_021320758.1	response regulator transcription factor	Regulator

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28904.26 Da
• Isoelectric Point: 7.8801

>NTDB_id=507766 I2438_RS05305 WP_021320758.1 1074668..1075405(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPYQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHRLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKLKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=507766 I2438_RS05305 WP_021320758.1 1074668..1075405(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ36]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAACAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACTTGTGATCGTTTTGAAGTTTATGGAAAGCCCTACCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATTGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAGGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAACGGGCAGTCTTGCATGGTTTCAAGACTAAAACTGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (18-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.719	98.776	0.531
comE/comE1	Streptococcus equinus JB1	45.868	98.776	0.453
comE/comE2	Streptococcus equinus JB1	37.295	99.592	0.371