Detailed information NTG0050752

Bioinformatically predicted

Overview

• Name: endA
• Type: Machinery gene
• Locus tag: SMULJ23_RS03150
• Genome accession: NC_017768
• Coordinates: 635643..636524 (+)
• Length: 293 a.a.
• NCBI ID: WP_002262935.1
• Uniprot ID: Q8DT59
• Organism: Streptococcus mutans LJ23
• Function: cleavage of dsDNA into ssDNA (predicted from homology) DNA processing

Genomic Context

Location: 630643..641524

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SMULJ23_RS03120 (SMULJ23_0591)	-	630827..631705 (+)	879	WP_002262941.1	F0F1 ATP synthase subunit gamma	-
SMULJ23_RS03125 (SMULJ23_0592)	atpD	631731..633137 (+)	1407	WP_002264827.1	F0F1 ATP synthase subunit beta	-
SMULJ23_RS03130 (SMULJ23_0593)	-	633151..633567 (+)	417	WP_002262939.1	F0F1 ATP synthase subunit epsilon	-
SMULJ23_RS03135 (SMULJ23_0594)	-	633840..634073 (+)	234	WP_002285829.1	DUF1146 family protein	-
SMULJ23_RS03140 (SMULJ23_0595)	murA	634139..635410 (+)	1272	WP_002262937.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
SMULJ23_RS03145 (SMULJ23_0596)	-	635413..635601 (+)	189	WP_002264826.1	DNA-directed RNA polymerase subunit beta	-
SMULJ23_RS03150 (SMULJ23_0597)	endA	635643..636524 (+)	882	WP_002262935.1	DNA/RNA non-specific endonuclease	Machinery gene
SMULJ23_RS03155 (SMULJ23_0598)	-	636593..637243 (-)	651	WP_002262934.1	amino acid ABC transporter permease	-
SMULJ23_RS03160 (SMULJ23_0599)	-	637258..637962 (-)	705	WP_002262933.1	amino acid ABC transporter permease	-
SMULJ23_RS03165 (SMULJ23_0600)	-	637980..638792 (-)	813	WP_002262932.1	transporter substrate-binding domain-containing protein	-
SMULJ23_RS03170 (SMULJ23_0601)	-	638789..639571 (-)	783	WP_002262931.1	amino acid ABC transporter ATP-binding protein	-
SMULJ23_RS03175 (SMULJ23_0602)	vicR	639924..640631 (+)	708	WP_002262930.1	response regulator YycF	Regulator

Sequence

Protein

• Length: 293 a.a.
• Molecular weight: 32130.72 Da
• Isoelectric Point: 9.5337

>NTDB_id=50752 SMULJ23_RS03150 WP_002262935.1 635643..636524(+) (endA) [Streptococcus mutans LJ23]
MTRKTNKSQRKQQKLCLSLLAALSVFVCTYIATSDHIADSNPIKQAAQLLTGKNKDILSNGSMSHQATPSQELANTVMTD
AVKNALGRQIEWSGAGSFIINHNKTDLNADVASQPYASNQTKIVQGQTVPTVANALLSKATRQYRNRQETGNGRTNWQPA
GWHQLYDLPGDYDHAVDRGHLLAYALVGGLKRFDASTSNPQNVATQAAWANEANSSNSRGQNYYETLIRKALDSHKRVRY
RVTLIYDDNNDILASGSHLEAKSSDGSLEFNVFIPNVQSGLTFDYATGQVKAN

Nucleotide

• Length: 882 bp

>NTDB_id=50752 SMULJ23_RS03150 WP_002262935.1 635643..636524(+) (endA) [Streptococcus mutans LJ23]
ATGACTAGAAAAACGAATAAGTCTCAGCGAAAACAGCAAAAATTATGCTTATCTCTCCTTGCTGCTTTGAGCGTATTTGT
TTGTACTTATATTGCAACCAGTGATCATATTGCTGATAGTAACCCTATAAAGCAGGCTGCCCAATTATTGACAGGTAAAA
ACAAGGATATACTTTCAAATGGTTCAATGAGCCATCAAGCGACTCCCAGTCAAGAATTAGCCAATACTGTTATGACGGAT
GCAGTAAAAAATGCCTTGGGTAGACAAATTGAATGGAGTGGTGCAGGTTCTTTCATTATTAATCATAATAAAACTGACCT
TAACGCTGATGTTGCTAGCCAACCGTATGCTAGTAATCAGACCAAAATCGTTCAAGGACAGACAGTACCAACAGTAGCAA
ATGCTTTGTTAAGTAAGGCTACTCGTCAGTACCGAAACCGTCAAGAGACAGGAAATGGCAGGACAAATTGGCAGCCAGCA
GGCTGGCATCAGCTTTATGATTTGCCGGGTGACTATGATCACGCGGTTGATCGTGGACACTTATTGGCTTATGCTTTGGT
TGGTGGTTTGAAACGATTTGATGCTTCAACGAGTAATCCTCAAAATGTAGCAACACAAGCAGCTTGGGCTAATGAAGCGA
ATAGTTCAAACTCAAGGGGACAAAATTATTATGAAACACTGATTAGAAAAGCTTTGGATAGTCATAAGCGTGTTCGTTAT
CGTGTGACTCTTATCTATGATGACAACAATGATATCTTAGCCAGTGGCAGTCATCTAGAAGCCAAATCATCAGATGGCAG
TCTAGAGTTCAATGTCTTTATTCCTAATGTTCAAAGCGGTTTGACCTTTGATTATGCAACAGGACAAGTTAAGGCAAATT
AA

Domains

Predicted by InterproScan.

• DNA/RNA non-specific endonuclease (Endonuclease_NS) (99-251)

3D structure

• AlphaFold DB: Q8DT59

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
endA	Streptococcus pneumoniae Rx1	64.103	79.863	0.512
endA	Streptococcus pneumoniae D39	64.103	79.863	0.512
endA	Streptococcus pneumoniae R6	64.103	79.863	0.512
endA	Streptococcus pneumoniae TIGR4	64.103	79.863	0.512