Detailed information    

insolico Bioinformatically predicted

Overview

Name   comD/blpH   Type   Regulator
Locus tag   SCI_RS11205 Genome accession   NC_022238
Coordinates   574992..576299 (-) Length   435 a.a.
NCBI ID   WP_020997678.1    Uniprot ID   -
Organism   Streptococcus constellatus subsp. pharyngis C1050     
Function   phosphorylation of ComE; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 569992..581299
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SCI_RS02910 (SCI_0578) - 570321..570695 (-) 375 WP_022525583.1 hypothetical protein -
  SCI_RS02915 (SCI_0579) comA/nlmT 571179..573329 (+) 2151 WP_006267089.1 peptide cleavage/export ABC transporter Regulator
  SCI_RS02920 (SCI_0580) - 573340..574701 (+) 1362 WP_020999319.1 bacteriocin secretion accessory protein -
  SCI_RS02925 (SCI_0581) - 574798..574947 (+) 150 WP_003037249.1 ComC/BlpC family leader-containing pheromone/bacteriocin -
  SCI_RS11205 (SCI_0582) comD/blpH 574992..576299 (-) 1308 WP_020997678.1 sensor histidine kinase Regulator
  SCI_RS02935 (SCI_0583) comE/blpR 576304..577050 (-) 747 WP_041786327.1 response regulator transcription factor Regulator
  SCI_RS02940 (SCI_0584) - 577219..577932 (-) 714 WP_020997680.1 CPBP family intramembrane glutamic endopeptidase -
  SCI_RS02945 (SCI_0585) - 578164..578385 (+) 222 WP_006267535.1 Blp family class II bacteriocin -
  SCI_RS02955 (SCI_0587) - 579062..579382 (+) 321 WP_006267159.1 hypothetical protein -
  SCI_RS02960 (SCI_0588) - 579390..579623 (+) 234 WP_003025420.1 garvicin Q family class II bacteriocin -
  SCI_RS02965 (SCI_0589) - 579675..579965 (+) 291 WP_006267076.1 bacteriocin immunity protein -
  SCI_RS02970 (SCI_0590) - 580115..580435 (+) 321 WP_006267110.1 hypothetical protein -

Sequence

Protein


Download         Length: 435 a.a.        Molecular weight: 50186.67 Da        Isoelectric Point: 7.9846

>NTDB_id=50683 SCI_RS11205 WP_020997678.1 574992..576299(-) (comD/blpH) [Streptococcus constellatus subsp. pharyngis C1050]
MVQLSLIIIDMFLLLFLFSYISGQKLTTRTYLIAILANLFYSIIFSFIPNNLFSYLIGPTYFLIFSWIVGKSYNKTLKIF
YGLFPITLWNLIQRLIIFFISPLFSFSVESLNKSFFGPIVTSIMATLIVLLFLHLIQYNFKTLKSQKINHNDKKIIIFVN
ISMIVYHLIVQVLSYLENESNIQTLNFRESLVVLYLILFVSVANYLDRHLRERIQNDLMLQKDLQLKNMENYSHHIEELY
TEVRSFRHDYANILTTLKLGIEQNDIGIVKNVYHSVLKDSNKRFRNPKYDIGRLVHIKNDALKSLLAAKFAQAQEHNVSV
SLEVPEDICPQGMELIDFITIVSILCDNAIEATTPTMTIAYVLSENKQVFSIENAIKEEHIDMSYIFDAGVSSKGSGRGI
GLSNVLAILDRYPNVSLTSASQNYRFQHVLEIHLN

Nucleotide


Download         Length: 1308 bp        

>NTDB_id=50683 SCI_RS11205 WP_020997678.1 574992..576299(-) (comD/blpH) [Streptococcus constellatus subsp. pharyngis C1050]
ATGGTGCAATTATCATTGATTATCATAGACATGTTTTTATTGTTGTTTCTGTTTTCCTACATTAGTGGACAAAAATTAAC
AACTAGAACATATCTGATAGCAATTCTAGCTAACTTATTTTATAGTATAATTTTTTCTTTTATTCCAAATAATTTATTTT
CTTATCTGATAGGTCCAACTTATTTTTTAATTTTTTCTTGGATTGTTGGAAAATCTTACAACAAAACATTAAAAATTTTT
TACGGACTTTTTCCAATCACACTATGGAATTTAATTCAACGCTTGATTATTTTTTTCATATCTCCTTTATTTAGTTTTAG
TGTAGAAAGCCTCAATAAAAGTTTTTTTGGTCCGATTGTCACCTCAATTATGGCAACGCTGATAGTATTACTTTTTTTGC
ATTTAATTCAATATAATTTTAAGACATTAAAATCTCAAAAAATTAATCACAACGATAAGAAAATTATCATCTTTGTAAAT
ATCAGCATGATTGTTTATCATCTTATTGTTCAAGTTCTATCTTATTTAGAAAACGAGAGTAACATACAGACACTAAATTT
TAGAGAAAGTTTAGTAGTTCTTTATCTTATCCTTTTTGTGAGTGTTGCCAATTATTTAGACCGTCATTTACGAGAGAGAA
TCCAAAATGATTTAATGCTTCAAAAAGATTTACAGTTAAAAAATATGGAAAACTACAGTCATCACATTGAGGAATTGTAC
ACAGAAGTTCGGAGCTTTCGGCATGATTACGCTAATATTTTAACAACCTTGAAATTAGGAATTGAGCAAAATGATATAGG
CATTGTAAAGAATGTCTATCATTCTGTTTTGAAAGATTCCAATAAGCGTTTTCGCAATCCCAAGTATGATATTGGACGGT
TAGTCCATATCAAAAACGATGCCTTAAAAAGCCTGCTAGCTGCTAAATTTGCACAAGCTCAAGAGCATAATGTATCCGTT
TCATTGGAGGTTCCAGAAGATATTTGTCCACAAGGAATGGAATTAATTGACTTTATCACCATTGTCTCCATTTTGTGTGA
TAATGCGATTGAAGCTACCACTCCAACTATGACGATTGCTTATGTTTTGTCAGAAAACAAGCAGGTATTCTCCATTGAAA
ATGCTATAAAAGAAGAGCATATAGACATGTCTTATATTTTTGATGCGGGAGTTAGTTCTAAAGGATCTGGGCGAGGAATT
GGATTATCAAATGTCTTAGCAATTCTGGATCGATATCCAAATGTTTCTCTTACTAGCGCTAGTCAAAATTATCGTTTCCA
GCATGTCCTTGAGATTCATCTGAATTAA

Domains

Predicted by InterProScan.

GHKL domain (HATPase_c_5)

(333-428)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comD/blpH Streptococcus mutans UA159

38.005

96.782

0.368

Multiple sequence alignment