Detailed information NTG0506544

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I2436_RS04845
• Genome accession: NZ_CP065060
• Coordinates: 1024668..1025405 (+)
• Length: 245 a.a.
• NCBI ID: WP_165622997.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ28
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1019668..1030405

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2436_RS04815 (GDAKBCAL_00960)	-	1020112..1021017 (-)	906	WP_012677986.1	diacylglycerol kinase family protein	-
I2436_RS04820 (GDAKBCAL_00961)	-	1021128..1021778 (-)	651	WP_043030784.1	hemolysin III family protein	-
I2436_RS04825 (GDAKBCAL_00962)	-	1021762..1022217 (-)	456	WP_037578258.1	DUF1836 domain-containing protein	-
I2436_RS04830 (GDAKBCAL_00963)	-	1022477..1023232 (+)	756	WP_043038959.1	class I SAM-dependent methyltransferase	-
I2436_RS04835 (GDAKBCAL_00964)	-	1023260..1023598 (+)	339	WP_206152590.1	cupin domain-containing protein	-
I2436_RS04840 (GDAKBCAL_00965)	-	1023600..1023905 (+)	306	WP_012515590.1	hypothetical protein	-
I2436_RS04845 (GDAKBCAL_00966)	comE/blpR	1024668..1025405 (+)	738	WP_165622997.1	response regulator transcription factor	Regulator
I2436_RS04850 (GDAKBCAL_00967)	-	1025778..1025978 (+)	201	WP_012515592.1	hypothetical protein	-
I2436_RS04855 (GDAKBCAL_00968)	-	1026045..1026899 (+)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
I2436_RS04860 (GDAKBCAL_00969)	-	1026905..1028068 (+)	1164	WP_014622845.1	ABC transporter permease subunit	-
I2436_RS04865 (GDAKBCAL_00970)	-	1028330..1028560 (+)	231	WP_012515596.1	Blp family class II bacteriocin	-
I2436_RS04870 (GDAKBCAL_00971)	-	1029353..1030204 (+)	852	WP_043025813.1	thioredoxin family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28868.25 Da
• Isoelectric Point: 7.8971

>NTDB_id=506544 I2436_RS04845 WP_165622997.1 1024668..1025405(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILHSQNERIEFYGFLSEVLKQDSRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALH

Nucleotide

• Length: 738 bp

>NTDB_id=506544 I2436_RS04845 WP_165622997.1 1024668..1025405(+) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ28]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAGCAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCTGTTGCTCGTGAGATCAGAAAGCGTGAC
CCTTATGCCCTCATTGTTTTTGTCACCACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACCCCTCACAAGTTGATTTTGCATTCTCAAAACGAGCGAATAGAATTTTACGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATTCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGCATTGA

Domains

Predicted by InterproScan.

• Response regulator receiver domain (Response_reg) (18-122)

• LytTr DNA-binding domain (LytTR) (151-240)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	53.719	98.776	0.531
comE/comE1	Streptococcus equinus JB1	45.455	98.776	0.449
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367