Detailed information NTG0506492

Bioinformatically predicted

Overview

• Name: comE/blpR
• Type: Regulator
• Locus tag: I2435_RS05495
• Genome accession: NZ_CP065059
• Coordinates: 1096298..1097035 (-)
• Length: 245 a.a.
• NCBI ID: WP_043040551.1
• Uniprot ID: -
• Organism: Streptococcus equi subsp. zooepidemicus strain SEZ25
• Function: activate transcription of early competence genes; regulation of comX expression (predicted from homology) Competence regulation

Genomic Context

Location: 1091298..1102035

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
I2435_RS05470 (JFMEOBDD_01102)	-	1091499..1092350 (-)	852	WP_206156274.1	thioredoxin family protein	-
I2435_RS05475 (JFMEOBDD_01103)	-	1093143..1093373 (-)	231	WP_012515596.1	Blp family class II bacteriocin	-
I2435_RS05480 (JFMEOBDD_01104)	-	1093635..1094798 (-)	1164	WP_206156275.1	ABC transporter permease subunit	-
I2435_RS05485 (JFMEOBDD_01105)	-	1094804..1095658 (-)	855	WP_012515593.1	ABC transporter ATP-binding protein	-
I2435_RS05490 (JFMEOBDD_01106)	-	1095725..1095925 (-)	201	WP_042670621.1	ComC/BlpC family leader-containing pheromone/bacteriocin	-
I2435_RS05495 (JFMEOBDD_01107)	comE/blpR	1096298..1097035 (-)	738	WP_043040551.1	response regulator transcription factor	Regulator
I2435_RS05500 (JFMEOBDD_01108)	-	1097799..1098104 (-)	306	WP_012677981.1	AraC family ligand binding domain-containing protein	-
I2435_RS05505 (JFMEOBDD_01109)	-	1098106..1098444 (-)	339	WP_014622843.1	cupin domain-containing protein	-
I2435_RS05510 (JFMEOBDD_01110)	-	1098472..1099227 (-)	756	WP_165628607.1	class I SAM-dependent methyltransferase	-
I2435_RS05515 (JFMEOBDD_01111)	-	1099487..1099942 (+)	456	WP_043030785.1	DUF1836 domain-containing protein	-
I2435_RS05520 (JFMEOBDD_01112)	-	1099926..1100576 (+)	651	WP_043030784.1	hemolysin III family protein	-
I2435_RS05525 (JFMEOBDD_01113)	-	1100686..1101591 (+)	906	WP_043030783.1	diacylglycerol kinase family protein	-

Sequence

Protein

• Length: 245 a.a.
• Molecular weight: 28930.36 Da
• Isoelectric Point: 7.8609

>NTDB_id=506492 I2435_RS05495 WP_043040551.1 1096298..1097035(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MNIFILEDDLGQQFRLEMKIQEILDKHHWTCDRFEVYGKPHQLLANVTERGRHQLFFLDSQIRNDEKKGLAVAREIRKRD
PYALIVFVTTHSELMPVSFRYQVSALDFIDKELSMKHFSDRIERAIIYAYEEQENVTSEGLFIFVTAKAQVQVPFSSLLF
IETSSTPHKLILYSQNERIEFYGFLSEVLKQDPRLVQCHRSYVINPYNVSFLDRDKRLLYFKNGQSCMVSRLKMKALEAS
IKALY

Nucleotide

• Length: 738 bp

>NTDB_id=506492 I2435_RS05495 WP_043040551.1 1096298..1097035(-) (comE/blpR) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
ATGAATATTTTTATTCTCGAAGATGATCTAGGCCAGCAGTTTAGGCTTGAGATGAAGATTCAAGAGATATTGGATAAGCA
TCACTGGACGTGTGATCGTTTTGAAGTTTATGGAAAGCCCCATCAGCTTCTGGCAAATGTTACAGAGAGAGGCAGGCATC
AGCTTTTCTTTCTCGATAGTCAAATTCGAAATGATGAGAAAAAGGGCTTAGCGGTTGCTCGTGAGATTAGAAAGCGTGAC
CCTTATGCTCTCATTGTTTTTGTCACGACACATTCTGAGCTTATGCCAGTTTCTTTTCGTTATCAGGTGTCTGCTCTAGA
TTTTATCGATAAGGAATTGTCAATGAAACATTTCTCAGATAGGATTGAAAGAGCCATTATATATGCTTATGAAGAGCAAG
AAAATGTAACCTCAGAGGGCTTATTTATTTTTGTAACGGCTAAGGCTCAGGTGCAGGTTCCTTTTTCAAGCCTATTGTTC
ATTGAGACCTCTAGTACTCCTCACAAGTTGATTTTGTATTCTCAAAACGAGCGAATAGAATTTTATGGCTTTCTTTCAGA
GGTTCTTAAGCAAGATCCCAGACTAGTCCAATGTCATCGTTCTTATGTTATCAATCCTTACAATGTTTCGTTTCTTGATC
GTGATAAGCGTTTACTCTATTTCAAGAATGGGCAGTCTTGCATGGTTTCAAGACTAAAAATGAAAGCACTTGAGGCGTCT
ATTAAGGCTTTGTATTGA

Domains

Predicted by InterproScan.

• LytTr DNA-binding domain (LytTR) (151-240)

• Response regulator receiver domain (Response_reg) (18-122)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/blpR	Streptococcus mutans UA159	54.132	98.776	0.535
comE/comE1	Streptococcus equinus JB1	45.041	98.776	0.445
comE/comE2	Streptococcus equinus JB1	36.885	99.592	0.367