Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYF   Type   Machinery gene
Locus tag   I2435_RS00745 Genome accession   NZ_CP065059
Coordinates   124971..125405 (+) Length   144 a.a.
NCBI ID   WP_206156890.1    Uniprot ID   -
Organism   Streptococcus equi subsp. zooepidemicus strain SEZ25     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
IScluster/Tn 125812..127154 124971..125405 flank 407


Gene organization within MGE regions


Location: 124971..127154
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I2435_RS00745 (JFMEOBDD_00148) comYF 124971..125405 (+) 435 WP_206156890.1 competence type IV pilus minor pilin ComGF Machinery gene
  I2435_RS00750 (JFMEOBDD_00149) comGG 125383..125745 (+) 363 WP_206156532.1 competence type IV pilus minor pilin ComGG -
  I2435_RS00755 - 125812..127154 (+) 1343 WP_206156533.1 IS3 family transposase -

Sequence

Protein


Download         Length: 144 a.a.        Molecular weight: 16067.55 Da        Isoelectric Point: 10.3349

>NTDB_id=506462 I2435_RS00745 WP_206156890.1 124971..125405(+) (comYF) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
MKGSRLKAFTLIECLIALLVISGSLLAYQALTKSLMANERYLAANDQNDWLLFSQQLRAELSGTTLQGVRNNRLYVEKDK
KALSFGQVKGHDFRKAASNGQGYQPMLFGLSSSQITAVGQQVTIKLKWQSGLERTFIYAFQEKG

Nucleotide


Download         Length: 435 bp        

>NTDB_id=506462 I2435_RS00745 WP_206156890.1 124971..125405(+) (comYF) [Streptococcus equi subsp. zooepidemicus strain SEZ25]
TTGAAAGGCAGTAGGCTAAAGGCTTTTACCTTGATAGAATGCCTTATTGCCTTGCTTGTCATCTCAGGCTCTCTATTAGC
CTATCAGGCCTTAACCAAGAGCCTTATGGCAAATGAGAGGTATCTAGCAGCAAATGATCAGAACGACTGGCTTTTGTTTT
CCCAGCAATTGCGAGCAGAGCTTTCAGGTACTACCCTACAGGGTGTCCGCAATAATAGGCTATATGTTGAAAAGGACAAG
AAGGCTTTGTCCTTTGGACAGGTCAAGGGTCATGATTTTAGAAAAGCAGCTAGCAATGGTCAAGGTTATCAGCCCATGCT
GTTTGGCTTGTCAAGTAGCCAAATAACAGCAGTAGGTCAGCAGGTGACCATCAAGCTGAAATGGCAAAGCGGCTTAGAAA
GGACCTTTATTTATGCATTTCAAGAGAAGGGTTAA

Domains

Predicted by InterproScan.

Putative Competence protein ComGF (ComGF)

(38-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYF Streptococcus mutans UA140

51.389

100

0.514
  comYF Streptococcus mutans UA159

50.694

100

0.507
  comGF/cglF Streptococcus mitis SK321

48.905

95.139

0.465
  comGF Lactococcus lactis subsp. cremoris KW2

47.482

96.528

0.458
  comGF/cglF Streptococcus mitis NCTC 12261

48.175

95.139

0.458
  comGF/cglF Streptococcus pneumoniae Rx1

45.07

98.611

0.444
  comGF/cglF Streptococcus pneumoniae D39

45.07

98.611

0.444
  comGF/cglF Streptococcus pneumoniae R6

45.07

98.611

0.444
  comGF/cglF Streptococcus pneumoniae TIGR4

45.07

98.611

0.444