Detailed information NTG0050569

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: SII_RS09045
• Genome accession: NC_022237
• Coordinates: 1855656..1858214 (-)
• Length: 852 a.a.
• NCBI ID: WP_020999244.1
• Uniprot ID: -
• Organism: Streptococcus intermedius C270
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1850656..1863214

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SII_RS09020 (SII_1774)	-	1851287..1851793 (+)	507	WP_020999239.1	helix-turn-helix domain-containing protein	-
SII_RS09025 (SII_1775)	-	1851777..1852286 (+)	510	WP_041823294.1	RDD family protein	-
SII_RS09030 (SII_1776)	hexB	1852432..1854378 (-)	1947	WP_020999241.1	DNA mismatch repair endonuclease MutL	Machinery gene
SII_RS09035 (SII_1777)	brsR	1854620..1855060 (+)	441	WP_041823295.1	LytTR family DNA-binding domain-containing protein	Regulator
SII_RS09040 (SII_1778)	-	1855057..1855515 (+)	459	WP_020999243.1	DUF3021 domain-containing protein	-
SII_RS09045 (SII_1779)	hexA	1855656..1858214 (-)	2559	WP_020999244.1	DNA mismatch repair protein MutS	Machinery gene
SII_RS09050 (SII_1780)	argR	1858377..1858817 (-)	441	WP_003075336.1	arginine repressor	-
SII_RS09055 (SII_1781)	argS	1858921..1860609 (+)	1689	WP_020999245.1	arginine--tRNA ligase	-
SII_RS09060 (SII_1782)	nrdI	1860661..1861116 (-)	456	WP_020999246.1	class Ib ribonucleoside-diphosphate reductase assembly flavoprotein NrdI	-
SII_RS09065 (SII_1783)	-	1861192..1861701 (-)	510	WP_020999247.1	hypothetical protein	-

Sequence

Protein

• Length: 852 a.a.
• Molecular weight: 96121.54 Da
• Isoelectric Point: 4.9309

>NTDB_id=50569 SII_RS09045 WP_020999244.1 1855656..1858214(-) (hexA) [Streptococcus intermedius C270]
MTKEKLSPGMQQYLDIKKDYPDAFLLFRMGDFYELFYEDAINAAQILEIALTSRNKNSEKPIPMAGVPYHSVQQYIDVLI
ESGYKVAIAEQVEDPKKAVGVVKREVVQVITPGTAVDSSKPDSQNNFLVALDKLEDFYGLAYMDVVTGEFQVTTLSDFNM
VCGEIRNLRAREVVLGYELPEAEHQVLANQMNLLLSQVETAFEDVQLLGDDLSRLEYQVAGKLLEYVHQTQLRELSHLKQ
VHHYEIKDFLQMDYATMTSLDLTENARTGKKHGSLYWLMDETKTAMGTRLLRRWIQHPLLDKERILKRQDVVQVFLNHFF
ERSDLADSLKGVYDIERLASRVSFGKTNPKDLLQLAATLSNVPQIKGILQGIDHPVLGQLIENLDDIPELANLIQSAISP
DAPNVITEGNIIQTGFDETLDKYRVVLRDGTSWIADIEAKEKAASGINNLKIDYNKKDGYYFHVTNSQLEHVPSHFFRKA
TLKNSERFGTEELARIEGEMLEAREKSANLEYEIFMRIREEAGKYIKRLQSLAQTLATIDVLQSFAAVAEKQRFVRPEFI
ERPSIEIDKGRHAVVEKVMGAQTYIPNSISMDENVNLQLITGPNMSGKSTYMRQLAIIVIMAQMGSYVSAERAQLPIFDA
IFTRIGAADDLVSGQSTFMVEMMEANHAISQATEHSLILFDELGRGTATYDGMALAQAIIEYIHNRTGAKTLFATHYHEL
TDLSTSLTQLENVHVATLEKDGQVTFLHKIEAGPADKSYGIHVARIAGLPNDLLMRADQILARLEEQANEKPSLNPSNKG
ANDSKENQVSEQISLFTETTESPILDELRQLDIYNMTPMEVMLAIAEMKKHL

Nucleotide

• Length: 2559 bp

>NTDB_id=50569 SII_RS09045 WP_020999244.1 1855656..1858214(-) (hexA) [Streptococcus intermedius C270]
ATGACAAAAGAAAAACTATCTCCGGGGATGCAACAGTATTTAGATATAAAAAAAGATTATCCGGATGCTTTTTTGCTATT
TCGCATGGGAGATTTTTATGAATTATTCTATGAAGATGCGATCAATGCAGCACAGATTTTAGAAATTGCTCTGACTAGCC
GTAATAAAAATTCGGAAAAGCCAATCCCGATGGCAGGAGTTCCCTATCATTCGGTGCAACAATATATTGATGTTTTAATT
GAATCGGGCTATAAAGTAGCGATTGCAGAGCAGGTGGAAGATCCTAAAAAAGCAGTTGGTGTAGTCAAACGTGAGGTGGT
ACAAGTCATCACACCGGGGACAGCCGTTGATTCTTCAAAACCAGATAGTCAAAATAATTTCTTGGTAGCTTTAGATAAGC
TAGAAGATTTCTATGGGCTAGCTTATATGGATGTGGTAACTGGTGAATTTCAGGTGACAACTCTCAGTGACTTTAACATG
GTTTGTGGGGAAATTCGAAATCTACGAGCGCGTGAAGTGGTGTTGGGATATGAATTACCTGAAGCAGAGCACCAAGTGTT
GGCAAATCAAATGAATTTGTTATTATCACAGGTGGAAACAGCTTTTGAAGATGTTCAGCTATTAGGAGATGATTTGTCTC
GCCTAGAATATCAAGTAGCTGGGAAACTGTTAGAATATGTTCACCAGACGCAACTGCGTGAGCTTAGTCACTTAAAGCAA
GTTCATCATTATGAAATTAAAGATTTCTTACAGATGGACTATGCAACTATGACAAGTCTAGATTTAACGGAGAATGCACG
GACGGGGAAGAAGCATGGCAGTCTTTATTGGTTGATGGACGAGACCAAGACAGCTATGGGGACGCGACTTCTAAGAAGAT
GGATCCAGCATCCGTTGCTTGATAAGGAACGGATTCTTAAGCGGCAGGATGTCGTACAAGTCTTTTTAAATCATTTTTTT
GAGCGTAGTGATTTGGCAGATAGTCTCAAAGGGGTTTATGATATTGAGCGCTTGGCAAGCCGTGTTTCTTTTGGGAAGAC
AAACCCGAAGGATTTATTGCAGTTGGCGGCAACATTGAGCAATGTCCCTCAGATTAAGGGAATTTTACAAGGAATCGATC
ATCCTGTTTTGGGACAGTTGATTGAAAACTTGGATGATATTCCAGAATTGGCAAACTTGATTCAGTCGGCAATTTCTCCT
GATGCTCCAAATGTTATTACTGAAGGGAATATCATTCAAACTGGTTTTGATGAAACCTTAGATAAGTATCGAGTGGTTCT
GCGAGATGGTACGAGCTGGATTGCTGATATTGAAGCGAAAGAAAAGGCAGCTAGTGGGATTAATAATCTAAAAATTGATT
ACAATAAAAAAGATGGTTATTATTTCCATGTTACTAATTCACAGTTGGAGCACGTACCTAGCCACTTTTTCCGAAAAGCA
ACGTTGAAAAATTCAGAACGATTTGGTACAGAGGAATTGGCTCGTATTGAAGGCGAAATGTTGGAAGCGCGTGAAAAATC
TGCTAATTTAGAATATGAGATTTTTATGCGTATTCGTGAAGAAGCTGGCAAATATATCAAGCGTCTGCAATCCTTGGCAC
AAACTCTGGCAACGATTGATGTATTACAAAGTTTTGCAGCAGTTGCTGAAAAGCAACGCTTTGTACGCCCAGAATTTATT
GAACGTCCTTCCATTGAAATTGATAAGGGACGGCATGCGGTTGTAGAAAAGGTTATGGGTGCACAAACTTATATTCCGAA
TAGTATTTCAATGGACGAGAATGTCAATCTTCAGCTAATTACAGGTCCAAATATGAGTGGGAAGTCAACCTATATGCGTC
AATTAGCGATTATTGTTATCATGGCGCAAATGGGTTCCTATGTTTCAGCTGAACGTGCTCAATTACCAATTTTTGATGCC
ATCTTCACTCGAATTGGTGCAGCAGATGACTTGGTATCTGGGCAATCAACCTTTATGGTAGAAATGATGGAAGCAAATCA
TGCTATTTCTCAAGCGACTGAACACTCTCTTATTCTTTTTGATGAGTTGGGAAGAGGGACAGCAACATATGATGGGATGG
CTCTTGCTCAGGCGATTATTGAATATATCCACAATCGAACAGGAGCAAAGACCCTTTTTGCCACACACTATCATGAGTTG
ACAGACTTGTCAACTAGCTTGACACAGTTAGAAAATGTTCATGTAGCAACTTTAGAAAAAGATGGGCAAGTGACCTTCCT
TCATAAGATTGAAGCTGGTCCTGCAGATAAGTCTTATGGGATTCATGTCGCAAGAATTGCAGGTTTACCAAATGATTTGT
TGATGAGAGCCGACCAGATACTAGCAAGACTAGAAGAACAAGCAAATGAGAAACCATCTCTCAATCCTTCTAATAAAGGA
GCTAATGATAGCAAGGAAAATCAAGTATCTGAGCAGATATCTTTATTCACAGAAACAACTGAATCACCTATTTTAGATGA
ACTACGTCAGTTGGATATTTATAATATGACCCCAATGGAAGTGATGCTAGCTATAGCTGAGATGAAAAAACATCTCTGA

Domains

Predicted by InterProScan.

• MutS domain II (MutS_II) (126-239)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain I (MutS_I) (8-118)

• MutS domain V (MutS_V) (599-785)

• MutS domain III (MutS_III) (255-546)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	75.235	100	0.752
mutS	Pseudomonas stutzeri strain ATCC 17587	36.543	100	0.37