Detailed information    

insolico Bioinformatically predicted

Overview

Name   comB8   Type   Machinery gene
Locus tag   HPSH112_RS00215 Genome accession   NC_017741
Coordinates   35634..36377 (+) Length   247 a.a.
NCBI ID   WP_000660502.1    Uniprot ID   A0A0E0WAE9
Organism   Helicobacter pylori Shi112     
Function   transformation-associated type IV transport system (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 30634..41377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HPSH112_RS00190 (HPSH112_00165) panD 32798..33148 (+) 351 WP_000142269.1 aspartate 1-decarboxylase -
  HPSH112_RS00195 (HPSH112_00170) - 33159..33452 (+) 294 WP_000347917.1 YbaB/EbfC family nucleoid-associated protein -
  HPSH112_RS00200 (HPSH112_00175) - 33452..34447 (+) 996 WP_000468441.1 PDZ domain-containing protein -
  HPSH112_RS00205 (HPSH112_00180) comB6 34453..35508 (+) 1056 WP_000786694.1 P-type conjugative transfer protein TrbL Machinery gene
  HPSH112_RS00210 comB7 35524..35637 (+) 114 WP_001217864.1 hypothetical protein Machinery gene
  HPSH112_RS00215 (HPSH112_00185) comB8 35634..36377 (+) 744 WP_000660502.1 type IV secretion system protein Machinery gene
  HPSH112_RS00220 (HPSH112_00190) comB9 36377..37333 (+) 957 WP_014662053.1 TrbG/VirB9 family P-type conjugative transfer protein Machinery gene
  HPSH112_RS00225 (HPSH112_00195) comB10 37326..38462 (+) 1137 WP_001045868.1 DNA type IV secretion system protein ComB10 Machinery gene
  HPSH112_RS00230 (HPSH112_00200) - 38534..39946 (+) 1413 WP_000694836.1 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase -
  HPSH112_RS00235 (HPSH112_00205) gmd 39961..41106 (+) 1146 WP_000659844.1 GDP-mannose 4,6-dehydratase -

Sequence

Protein


Download         Length: 247 a.a.        Molecular weight: 28599.81 Da        Isoelectric Point: 8.9830

>NTDB_id=50531 HPSH112_RS00215 WP_000660502.1 35634..36377(+) (comB8) [Helicobacter pylori Shi112]
MKEKPFNSEQLAFLEELLSHQEKHLENKLSGFSVSDLDMQSVFRLERNRLKIAYKLLGLMSFIALILAIVLISVLPLQKT
EHHFVDFLNQDKHYAIIQRADKSISSNEALARSLIGAYVLNRESINRIDDKSRYELVRLQSSSKVWQRFEDLIKTQNSIY
AQSHLEREVHIVNIAIYQQDNNPIASVSIAAKLMNENKLVYEKRYKIALSYLFDTPDFDYASMPKNPTGFKITRYSITEI
APTNRGD

Nucleotide


Download         Length: 744 bp        

>NTDB_id=50531 HPSH112_RS00215 WP_000660502.1 35634..36377(+) (comB8) [Helicobacter pylori Shi112]
ATGAAAGAAAAGCCTTTCAATAGCGAGCAGTTGGCTTTTTTAGAAGAGCTTTTAAGCCACCAAGAAAAGCATTTAGAAAA
CAAGCTTTCTGGTTTTTCGGTGAGTGATTTGGACATGCAAAGCGTGTTCAGATTAGAGAGGAACCGCTTGAAAATCGCTT
ATAAACTCTTAGGTTTGATGAGTTTTATCGCTCTTATCTTGGCGATCGTGTTAATCAGTGTTTTACCCCTACAAAAAACC
GAACACCATTTCGTGGATTTTTTAAACCAGGACAAGCATTACGCCATTATCCAAAGAGCGGATAAAAGCATTTCCAGTAA
TGAAGCGTTGGCTCGTTCGCTCATTGGGGCGTATGTGTTAAACAGGGAGAGCATTAATCGCATTGACGATAAATCGCGCT
ATGAATTGGTGCGCTTGCAAAGCAGTTCTAAAGTGTGGCAACGCTTTGAAGATTTGATTAAAACCCAAAACAGCATTTAT
GCGCAAAGCCATCTGGAAAGAGAAGTCCATATCGTCAATATTGCGATCTATCAGCAAGACAATAACCCCATTGCGAGCGT
TTCTATTGCAGCTAAACTCATGAATGAAAACAAACTGGTGTATGAAAAGCGTTATAAAATCGCGCTGAGTTATTTGTTTG
ACACCCCGGATTTTGATTACGCTTCCATGCCCAAAAACCCTACCGGTTTTAAAATCACTCGCTACAGCATCACTGAAATT
GCGCCGACTAATAGGGGCGATTGA

Domains

Predicted by InterproScan.

VirB8 protein (VirB8)

(38-239)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0E0WAE9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comB8 Helicobacter pylori P1

97.166

100

0.972

Multiple sequence alignment