Detailed information
Bioinformatically predicted
Overview
| Name | comB10 | Type | Machinery gene |
| Locus tag | HCW_RS08160 | Genome accession | NC_017737 |
| Coordinates | 1774631..1775833 (+) | Length | 400 a.a. |
| NCBI ID | WP_014661741.1 | Uniprot ID | - |
| Organism | Helicobacter cetorum MIT 00-7128 | ||
| Function | transformation-associated type IV transport system (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1763744..1821806 | 1774631..1775833 | within | 0 |
Gene organization within MGE regions
Location: 1763744..1821806
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| HCW_RS09155 (HCW_08030) | - | 1764852..1766480 (+) | 1629 | WP_014661730.1 | McrB family protein | - |
| HCW_RS08105 (HCW_08035) | - | 1766464..1766793 (+) | 330 | WP_014661731.1 | hypothetical protein | - |
| HCW_RS08110 (HCW_08040) | - | 1766841..1767629 (+) | 789 | WP_014661732.1 | hypothetical protein | - |
| HCW_RS08120 (HCW_08045) | - | 1767859..1768338 (+) | 480 | WP_014661733.1 | hypothetical protein | - |
| HCW_RS08125 (HCW_08050) | comB2 | 1768335..1768625 (+) | 291 | WP_014661734.1 | TrbC/VirB2 family protein | Machinery gene |
| HCW_RS08130 (HCW_08055) | comB3 | 1768635..1768898 (+) | 264 | WP_014661735.1 | hypothetical protein | Machinery gene |
| HCW_RS08135 (HCW_08060) | - | 1768909..1769145 (+) | 237 | WP_014661736.1 | hypothetical protein | - |
| HCW_RS08140 (HCW_08065) | - | 1769145..1771688 (+) | 2544 | WP_014661737.1 | VirB4 family type IV secretion/conjugal transfer ATPase | - |
| HCW_RS10050 (HCW_08070) | - | 1771689..1771829 (+) | 141 | WP_014661738.1 | hypothetical protein | - |
| HCW_RS08150 (HCW_08075) | - | 1771822..1772964 (+) | 1143 | WP_014661739.1 | VirB8/TrbF family protein | - |
| HCW_RS08155 (HCW_08080) | - | 1772961..1774634 (+) | 1674 | WP_014661740.1 | TrbG/VirB9 family P-type conjugative transfer protein | - |
| HCW_RS08160 (HCW_08085) | comB10 | 1774631..1775833 (+) | 1203 | WP_014661741.1 | DNA type IV secretion system protein ComB10 | Machinery gene |
| HCW_RS08165 (HCW_08090) | - | 1775817..1778072 (+) | 2256 | WP_014661742.1 | hypothetical protein | - |
| HCW_RS08170 (HCW_08095) | - | 1778086..1779036 (+) | 951 | WP_014661743.1 | membrane protein | - |
| HCW_RS08175 (HCW_08100) | - | 1779054..1779329 (+) | 276 | WP_014661744.1 | hypothetical protein | - |
| HCW_RS08180 (HCW_08105) | - | 1779334..1780281 (+) | 948 | WP_014661745.1 | ATPase, T2SS/T4P/T4SS family | - |
| HCW_RS08185 (HCW_08110) | - | 1780278..1780796 (+) | 519 | WP_014661746.1 | hypothetical protein | - |
| HCW_RS08190 (HCW_08115) | - | 1780793..1783027 (+) | 2235 | WP_014661747.1 | type IV secretory system conjugative DNA transfer family protein | - |
| HCW_RS08195 (HCW_08120) | - | 1783155..1795178 (+) | 12024 | WP_419470993.1 | SNF2-related protein | - |
| HCW_RS08200 (HCW_08125) | - | 1795298..1795816 (+) | 519 | WP_014661011.1 | hypothetical protein | - |
| HCW_RS08205 (HCW_08130) | - | 1795826..1796272 (+) | 447 | WP_014661010.1 | hypothetical protein | - |
| HCW_RS08210 (HCW_08135) | - | 1796292..1796573 (+) | 282 | WP_014661009.1 | hypothetical protein | - |
| HCW_RS09495 | - | 1796570..1796746 (+) | 177 | WP_155802237.1 | hypothetical protein | - |
| HCW_RS08215 (HCW_08140) | - | 1796759..1796965 (+) | 207 | WP_014661008.1 | hypothetical protein | - |
| HCW_RS08220 (HCW_08145) | - | 1796965..1797720 (+) | 756 | WP_014661749.1 | hypothetical protein | - |
| HCW_RS08225 (HCW_08150) | - | 1797724..1798077 (+) | 354 | WP_014661750.1 | hypothetical protein | - |
| HCW_RS09500 (HCW_08155) | - | 1798074..1798226 (+) | 153 | WP_014661751.1 | hypothetical protein | - |
| HCW_RS08230 (HCW_08160) | - | 1798226..1798750 (+) | 525 | WP_014661752.1 | hypothetical protein | - |
| HCW_RS08235 (HCW_08165) | - | 1798762..1800825 (+) | 2064 | WP_014661753.1 | type IA DNA topoisomerase | - |
| HCW_RS08240 (HCW_08170) | - | 1800880..1801347 (+) | 468 | WP_014661754.1 | hypothetical protein | - |
| HCW_RS08245 (HCW_08175) | - | 1801317..1802111 (+) | 795 | WP_014661755.1 | nucleotidyl transferase AbiEii/AbiGii toxin family protein | - |
| HCW_RS08250 (HCW_08180) | - | 1802174..1802809 (-) | 636 | WP_043902694.1 | hypothetical protein | - |
| HCW_RS08255 (HCW_08185) | - | 1802787..1803163 (-) | 377 | Protein_1629 | hypothetical protein | - |
| HCW_RS08260 (HCW_08190) | - | 1803210..1803878 (-) | 669 | WP_014661758.1 | ParA family protein | - |
| HCW_RS09505 | - | 1804186..1804359 (-) | 174 | WP_155802267.1 | hypothetical protein | - |
| HCW_RS08265 (HCW_08195) | - | 1804365..1804691 (-) | 327 | WP_014661759.1 | hypothetical protein | - |
| HCW_RS08270 (HCW_08200) | - | 1804701..1805078 (-) | 378 | WP_014661760.1 | hypothetical protein | - |
| HCW_RS09610 (HCW_08205) | - | 1805643..1805807 (+) | 165 | WP_014661761.1 | hypothetical protein | - |
| HCW_RS08275 (HCW_08210) | - | 1805808..1806863 (+) | 1056 | WP_014661762.1 | ArdC family protein | - |
| HCW_RS08280 (HCW_08215) | - | 1806863..1809187 (+) | 2325 | WP_014661763.1 | hypothetical protein | - |
| HCW_RS08285 (HCW_08220) | - | 1809197..1810630 (+) | 1434 | WP_014661764.1 | hypothetical protein | - |
| HCW_RS08290 (HCW_08225) | - | 1810627..1811889 (+) | 1263 | WP_014661765.1 | type IV secretion system protein | - |
| HCW_RS08295 (HCW_08230) | - | 1811886..1813154 (+) | 1269 | WP_014661766.1 | hypothetical protein | - |
| HCW_RS08300 (HCW_08235) | - | 1813175..1813903 (-) | 729 | WP_014661767.1 | hypothetical protein | - |
| HCW_RS08305 (HCW_08240) | - | 1814121..1814798 (+) | 678 | WP_014661768.1 | CAAX amino protease | - |
| HCW_RS08310 (HCW_08245) | - | 1815094..1815360 (-) | 267 | WP_014661769.1 | hypothetical protein | - |
| HCW_RS08315 (HCW_08250) | ctkA | 1815639..1816619 (+) | 981 | WP_014661770.1 | serine/threonine-protein kinase CtkA | - |
| HCW_RS08320 (HCW_08255) | - | 1816917..1817984 (-) | 1068 | WP_014661771.1 | tyrosine-type recombinase/integrase | - |
| HCW_RS08325 (HCW_08260) | - | 1818828..1820855 (-) | 2028 | WP_014661772.1 | relaxase/mobilization nuclease domain-containing protein | - |
Sequence
Protein
Download Length: 400 a.a. Molecular weight: 44852.51 Da Isoelectric Point: 10.2066
>NTDB_id=50480 HCW_RS08160 WP_014661741.1 1774631..1775833(+) (comB10) [Helicobacter cetorum MIT 00-7128]
MNKSLLKKIGLGALGAITLMALGILANKNQNQNNQEEIFQVSESKFPLSDYFFEEVKEEPKEKAKETTQTTTQQPTTQAN
VSTNPIVVGYNPLNHSLNNQNSTLNHLQNVLQQKPKEKSKKTKHTKEQLEFLNTRLKPLEPLKNATKPETEYGVDSFTNL
KYKDVGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFANMGRAVLIPKGSKVIGYYNNNNQIGEYRLNIA
WTRIITPQGINIMLTNARGADVKGYNGLIGKVIKRNFERYGLPLLTSTLSNGLLIGLTSALANRQNKAGVGNPFFGDYLL
MQLTRNTGMSINQVINQMLRQNARQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKKQNEEISNEDEI
MNKSLLKKIGLGALGAITLMALGILANKNQNQNNQEEIFQVSESKFPLSDYFFEEVKEEPKEKAKETTQTTTQQPTTQAN
VSTNPIVVGYNPLNHSLNNQNSTLNHLQNVLQQKPKEKSKKTKHTKEQLEFLNTRLKPLEPLKNATKPETEYGVDSFTNL
KYKDVGTNEHKLLRTITADRMIPAFLITPISSQIAGKVTAQVESDIFANMGRAVLIPKGSKVIGYYNNNNQIGEYRLNIA
WTRIITPQGINIMLTNARGADVKGYNGLIGKVIKRNFERYGLPLLTSTLSNGLLIGLTSALANRQNKAGVGNPFFGDYLL
MQLTRNTGMSINQVINQMLRQNARQNPIIIIREGSRVFISPNLDIFIPKPKDGEVLAEFFKEKKPLIKKQNEEISNEDEI
Nucleotide
Download Length: 1203 bp
>NTDB_id=50480 HCW_RS08160 WP_014661741.1 1774631..1775833(+) (comB10) [Helicobacter cetorum MIT 00-7128]
ATGAATAAATCGTTGCTTAAAAAGATAGGCTTAGGCGCTTTAGGTGCTATTACTTTAATGGCACTAGGCATACTTGCTAA
TAAAAATCAAAACCAAAATAACCAAGAAGAAATCTTTCAAGTAAGCGAGAGTAAATTCCCACTAAGCGATTATTTCTTTG
AAGAAGTCAAAGAAGAACCAAAAGAAAAAGCAAAAGAAACTACGCAAACAACTACACAACAACCTACAACGCAAGCTAAT
GTTTCAACTAATCCTATTGTCGTGGGTTACAACCCCCTTAATCATAGTCTTAATAATCAAAATAGCACACTTAATCATTT
GCAAAATGTTTTACAGCAAAAGCCAAAAGAAAAATCCAAAAAAACAAAGCACACCAAAGAGCAATTAGAGTTTTTAAATA
CACGCCTTAAACCCCTAGAGCCTTTAAAGAATGCCACTAAGCCAGAGACTGAATATGGTGTGGATAGTTTTACTAATTTG
AAGTATAAAGATGTCGGCACTAATGAGCATAAGCTTTTAAGAACTATTACAGCTGATAGAATGATACCAGCTTTTTTAAT
CACGCCTATTAGCTCTCAAATTGCTGGCAAAGTAACCGCTCAAGTAGAGAGTGATATATTTGCTAATATGGGAAGAGCGG
TGCTAATTCCTAAAGGCTCTAAGGTTATAGGTTATTACAACAACAATAACCAAATTGGCGAATACCGCCTAAATATTGCT
TGGACTAGAATTATCACCCCTCAAGGCATAAACATTATGCTCACTAATGCAAGGGGAGCTGATGTAAAGGGCTATAATGG
TCTAATTGGCAAAGTCATTAAGCGTAATTTTGAACGCTATGGACTTCCTTTACTCACTTCCACACTCTCTAATGGGCTTT
TAATAGGCTTAACTTCAGCCCTAGCTAATAGACAAAATAAAGCAGGTGTAGGCAATCCTTTTTTTGGGGATTACTTACTT
ATGCAACTCACTAGAAATACAGGCATGAGTATCAATCAAGTCATCAATCAAATGTTAAGACAAAACGCTAGACAAAACCC
CATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATTTTTATCCCTAAGCCTAAAGATGGGG
AAGTTCTAGCAGAGTTTTTTAAGGAGAAAAAACCATTGATTAAAAAACAAAACGAGGAAATTAGCAATGAAGATGAAATC
TAA
ATGAATAAATCGTTGCTTAAAAAGATAGGCTTAGGCGCTTTAGGTGCTATTACTTTAATGGCACTAGGCATACTTGCTAA
TAAAAATCAAAACCAAAATAACCAAGAAGAAATCTTTCAAGTAAGCGAGAGTAAATTCCCACTAAGCGATTATTTCTTTG
AAGAAGTCAAAGAAGAACCAAAAGAAAAAGCAAAAGAAACTACGCAAACAACTACACAACAACCTACAACGCAAGCTAAT
GTTTCAACTAATCCTATTGTCGTGGGTTACAACCCCCTTAATCATAGTCTTAATAATCAAAATAGCACACTTAATCATTT
GCAAAATGTTTTACAGCAAAAGCCAAAAGAAAAATCCAAAAAAACAAAGCACACCAAAGAGCAATTAGAGTTTTTAAATA
CACGCCTTAAACCCCTAGAGCCTTTAAAGAATGCCACTAAGCCAGAGACTGAATATGGTGTGGATAGTTTTACTAATTTG
AAGTATAAAGATGTCGGCACTAATGAGCATAAGCTTTTAAGAACTATTACAGCTGATAGAATGATACCAGCTTTTTTAAT
CACGCCTATTAGCTCTCAAATTGCTGGCAAAGTAACCGCTCAAGTAGAGAGTGATATATTTGCTAATATGGGAAGAGCGG
TGCTAATTCCTAAAGGCTCTAAGGTTATAGGTTATTACAACAACAATAACCAAATTGGCGAATACCGCCTAAATATTGCT
TGGACTAGAATTATCACCCCTCAAGGCATAAACATTATGCTCACTAATGCAAGGGGAGCTGATGTAAAGGGCTATAATGG
TCTAATTGGCAAAGTCATTAAGCGTAATTTTGAACGCTATGGACTTCCTTTACTCACTTCCACACTCTCTAATGGGCTTT
TAATAGGCTTAACTTCAGCCCTAGCTAATAGACAAAATAAAGCAGGTGTAGGCAATCCTTTTTTTGGGGATTACTTACTT
ATGCAACTCACTAGAAATACAGGCATGAGTATCAATCAAGTCATCAATCAAATGTTAAGACAAAACGCTAGACAAAACCC
CATTATCATCATTAGAGAGGGGAGCAGAGTGTTTATTAGCCCTAATTTAGACATTTTTATCCCTAAGCCTAAAGATGGGG
AAGTTCTAGCAGAGTTTTTTAAGGAGAAAAAACCATTGATTAAAAAACAAAACGAGGAAATTAGCAATGAAGATGAAATC
TAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comB10 | Helicobacter pylori P1 |
53.944 |
98.25 |
0.53 |