Detailed information NTG0050441

Bioinformatically predicted

Overview

• Name: comB10
• Type: Machinery gene
• Locus tag: HCD_RS00100
• Genome accession: NC_017735
• Coordinates: 17127..18260 (-)
• Length: 377 a.a.
• NCBI ID: WP_014658576.1
• Uniprot ID: I0EQ28
• Organism: Helicobacter cetorum MIT 99-5656
• Function: transformation-associated type IV transport system (predicted from homology) DNA binding and uptake

Genomic Context

Location: 12127..23260

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
HCD_RS00085 (HCD_00055)	-	13594..14535 (-)	942	WP_014658574.1	GDP-L-fucose synthase family protein	-
HCD_RS00090 (HCD_00060)	gmd	14528..15673 (-)	1146	WP_014658575.1	GDP-mannose 4,6-dehydratase	-
HCD_RS00095	-	15670..17087 (-)	1418	Protein_15	mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase	-
HCD_RS00100 (HCD_00075)	comB10	17127..18260 (-)	1134	WP_014658576.1	DNA type IV secretion system protein ComB10	Machinery gene
HCD_RS00105 (HCD_00080)	comB9	18257..19186 (-)	930	WP_014658577.1	TrbG/VirB9 family P-type conjugative transfer protein	Machinery gene
HCD_RS00110 (HCD_00085)	comB8	19186..19923 (-)	738	WP_014658578.1	type IV secretion system protein	Machinery gene
HCD_RS09485 (HCD_00090)	comB7	19920..20033 (-)	114	WP_014658579.1	hypothetical protein	Machinery gene
HCD_RS00115 (HCD_00095)	comB6	20049..21095 (-)	1047	WP_014658580.1	P-type conjugative transfer protein TrbL	Machinery gene
HCD_RS00120 (HCD_00100)	-	21095..22090 (-)	996	WP_014658581.1	PDZ domain-containing protein	-
HCD_RS00125 (HCD_00105)	-	22090..22383 (-)	294	WP_014658582.1	YbaB/EbfC family nucleoid-associated protein	-
HCD_RS00130 (HCD_00110)	panD	22386..22742 (-)	357	WP_014658583.1	aspartate 1-decarboxylase	-

Sequence

Protein

• Length: 377 a.a.
• Molecular weight: 42376.95 Da
• Isoelectric Point: 9.7882

>NTDB_id=50441 HCD_RS00100 WP_014658576.1 17127..18260(-) (comB10) [Helicobacter cetorum MIT 99-5656]
MNKWLKGVLIFVGCFVVIMATSLIYHKKPKAPLNNQPNLLSDDEVKYPLGDYTFTQNSNQTNKDSSKDATIKALQQQLQT
ALKALNSQKISPPRQEIPQDFTKPTTKTNHSKRDFSLEQLDLLASRITPFEESPKNYEENLIFPIDSSKGIDSFTNLKDK
DIATNENKLLRTITADKMIPAFLITPISSQIAGKVIAQVESDIFANMGRAVLIPKGSKVIGYYNNNNKMGEYRLDIVWTR
IITPHGINIMLTNAKGADIKGYNGLVGELIERNFQRYGMPLLLSTLTNGLLIGLTSALNNKGNKEETTNFFGDYLLMQMM
RQSGMGINQVINQILRDKSKIVPIVVIREGSRVFISPNTDIFFPIPRENEVIAEFLK

Nucleotide

• Length: 1134 bp

>NTDB_id=50441 HCD_RS00100 WP_014658576.1 17127..18260(-) (comB10) [Helicobacter cetorum MIT 99-5656]
ATGAATAAATGGCTTAAAGGGGTGCTTATTTTTGTAGGGTGTTTTGTAGTGATTATGGCTACTTCTTTAATCTATCATAA
AAAACCAAAAGCCCCTTTAAATAACCAACCAAATCTCTTAAGTGATGATGAAGTGAAATACCCCTTAGGCGACTATACTT
TCACTCAAAATTCAAACCAAACTAACAAAGACAGCTCCAAAGACGCTACCATAAAAGCCTTACAACAACAGCTACAAACC
GCCCTAAAAGCCTTAAATTCTCAAAAAATCAGCCCCCCTAGACAAGAAATTCCACAAGATTTCACAAAGCCTACCACAAA
GACAAACCACTCCAAAAGAGACTTTTCTTTAGAGCAATTAGATTTATTAGCCTCTCGTATAACCCCCTTTGAAGAAAGCC
CTAAAAACTACGAAGAAAACCTTATTTTTCCTATAGATTCTTCTAAAGGCATAGATAGTTTTACTAATCTTAAAGACAAA
GACATCGCCACGAATGAAAACAAGCTTTTAAGAACCATTACTGCAGATAAAATGATACCAGCCTTTTTAATCACGCCCAT
TTCTAGTCAAATCGCTGGTAAGGTCATCGCCCAAGTAGAGAGCGATATTTTTGCGAATATGGGAAGAGCGGTGCTTATTC
CTAAAGGCTCTAAAGTCATCGGCTATTACAATAATAATAACAAAATGGGGGAATATCGCCTAGATATTGTATGGACTAGG
ATTATCACACCCCATGGCATAAATATCATGCTCACTAACGCTAAAGGAGCGGATATTAAGGGCTATAATGGCTTAGTTGG
CGAACTCATTGAAAGGAATTTCCAACGCTATGGCATGCCCTTACTTCTTTCTACGCTCACTAATGGCTTATTGATAGGCT
TAACTTCTGCTTTAAACAATAAGGGCAACAAGGAAGAAACAACGAATTTTTTTGGAGATTATCTCTTAATGCAAATGATG
AGACAAAGTGGCATGGGGATTAACCAAGTTATCAATCAAATTTTAAGAGATAAGAGTAAAATTGTCCCTATTGTAGTCAT
TAGAGAAGGGAGTAGGGTATTCATCTCGCCAAATACGGATATTTTTTTTCCTATACCTAGAGAGAATGAAGTCATCGCTG
AGTTTTTGAAGTAG

Domains

Predicted by InterproScan.

• Bacterial conjugation TrbI-like protein (TrbI) (172-363)

3D structure

• AlphaFold DB: I0EQ28

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comB10	Helicobacter pylori P1	82.586	100	0.83