Detailed information NTG0050417

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: SCRE_RS05705
• Genome accession: NC_022236
• Coordinates: 1145842..1146846 (-)
• Length: 334 a.a.
• NCBI ID: WP_003068684.1
• Uniprot ID: U2XVW3
• Organism: Streptococcus constellatus subsp. pharyngis C232
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1140842..1151846

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SCRE_RS05685 (SCRE_1119)	yycF	1142076..1142777 (-)	702	WP_003035055.1	response regulator YycF	-
SCRE_RS05690 (SCRE_1120)	-	1143078..1143410 (-)	333	WP_006268722.1	hypothetical protein	-
SCRE_RS05695 (SCRE_1121)	-	1143437..1144750 (-)	1314	WP_006268747.1	glycosyltransferase family 4 protein	-
SCRE_RS05700 (SCRE_1122)	-	1144752..1145750 (-)	999	WP_020997876.1	glycosyltransferase family 4 protein	-
SCRE_RS05705 (SCRE_1123)	ccpA	1145842..1146846 (-)	1005	WP_003068684.1	catabolite control protein A	Regulator
SCRE_RS05710 (SCRE_1124)	-	1147111..1148193 (+)	1083	WP_020997877.1	M24 family metallopeptidase	-
SCRE_RS05715 (SCRE_1125)	-	1148716..1149297 (-)	582	WP_006268725.1	class I SAM-dependent methyltransferase	-
SCRE_RS05720 (SCRE_1126)	galE	1149616..1150635 (-)	1020	WP_020997878.1	UDP-glucose 4-epimerase GalE	-
SCRE_RS05725 (SCRE_1127)	rfbB	1150670..1151716 (-)	1047	WP_020997879.1	dTDP-glucose 4,6-dehydratase	-

Sequence

Protein

• Length: 334 a.a.
• Molecular weight: 37056.22 Da
• Isoelectric Point: 6.1741

>NTDB_id=50417 SCRE_RS05705 WP_003068684.1 1145842..1146846(-) (ccpA) [Streptococcus constellatus subsp. pharyngis C232]
MNTDDTVTIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNITSSYFA
TLAKGIDDIAEMYKYNIVLANSDEDDDKEVSVVNTLFSKQVDGIIFMGYHLTEKIRSEFSRSRTPVVLAGTVDVEHQLPS
VNIDYKQATMDAVERLTKNNKKIAFVSGPLVDDINGKIRLIGYKEALKKAKLSYSEGLVFESKYSYEDGYQLAERVIASK
ATAAFVTGDELAAGLLNGLSDKGVNIPEDFEIITSDDSQVARFTRPNLTTIGQPLYDLGAISMRMLTKIMHKEELEEREV
VLAHGLIERRSTRK

Nucleotide

• Length: 1005 bp

>NTDB_id=50417 SCRE_RS05705 WP_003068684.1 1145842..1146846(-) (ccpA) [Streptococcus constellatus subsp. pharyngis C232]
ATGAACACAGACGATACTGTAACGATTTATGATGTCGCCCGTGAAGCGGGAGTTTCAATGGCGACCGTTAGCCGTGTCGT
AAACGGCAATAAAAATGTAAAGGAAAATACAAGAAAAAAAGTCTTGGAAGTCATTGATCGCCTTGACTATCGACCAAATG
CAGTTGCTCGTGGACTTGCCAGTAAGAAAACGACAACAGTAGGAGTTGTCATTCCAAACATTACAAGCAGTTATTTTGCA
ACGCTTGCGAAAGGAATTGATGACATCGCAGAGATGTATAAGTATAATATTGTTTTGGCAAATAGTGATGAGGATGATGA
CAAGGAAGTTTCTGTTGTCAATACCTTGTTCTCAAAACAAGTGGACGGCATTATCTTTATGGGATATCATCTAACAGAAA
AGATTCGTTCTGAGTTTTCTCGTTCAAGGACGCCGGTTGTACTTGCAGGAACGGTTGACGTGGAACATCAATTGCCAAGT
GTTAATATTGATTACAAACAAGCAACTATGGATGCAGTAGAGCGCCTCACTAAAAACAATAAAAAAATTGCTTTTGTGAG
TGGACCTTTGGTAGATGATATAAATGGTAAGATTCGTTTAATTGGTTACAAAGAAGCGTTGAAAAAAGCAAAACTTTCTT
ATAGTGAAGGGCTTGTCTTTGAGTCTAAATACAGCTATGAGGATGGCTATCAATTGGCAGAGCGTGTCATTGCTTCTAAA
GCGACAGCAGCCTTTGTGACTGGTGATGAACTGGCAGCTGGATTGTTAAATGGCTTATCAGACAAAGGTGTAAATATACC
AGAAGATTTTGAAATCATTACTAGTGATGATTCGCAGGTAGCACGTTTTACTCGTCCAAATTTGACGACAATTGGACAAC
CTTTGTACGATCTTGGTGCGATTAGTATGCGCATGTTGACTAAGATTATGCACAAGGAAGAGTTGGAAGAACGTGAAGTG
GTGTTAGCTCATGGTCTTATTGAGCGCCGTTCAACAAGGAAGTAA

Domains

Predicted by InterProScan.

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

• Periplasmic binding protein-like domain (Peripla_BP_3) (181-332)

3D structure

• AlphaFold DB: U2XVW3

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	90.719	100	0.907
ccpA	Streptococcus pneumoniae D39	87.725	100	0.877
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	58.308	99.102	0.578