Detailed information NTG0504109

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: KRG72_RS08890
• Genome accession: NZ_CP076703
• Coordinates: 1794770..1797337 (-)
• Length: 855 a.a.
• NCBI ID: WP_258255168.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain S1
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 1789770..1802337

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS08870 (KRG72_08870)	-	1790151..1791332 (-)	1182	WP_258255160.1	MFS transporter	-
KRG72_RS08875 (KRG72_08875)	-	1791535..1792086 (-)	552	WP_258255161.1	DNA-3-methyladenine glycosylase I	-
KRG72_RS08880 (KRG72_08880)	ruvA	1792116..1792709 (-)	594	WP_074869549.1	Holliday junction branch migration protein RuvA	Machinery gene
KRG72_RS08885 (KRG72_08885)	hexB	1792710..1794650 (-)	1941	WP_258255164.1	DNA mismatch repair endonuclease MutL	Machinery gene
KRG72_RS08890 (KRG72_08890)	hexA	1794770..1797337 (-)	2568	WP_258255168.1	DNA mismatch repair protein MutS	Machinery gene
KRG72_RS08895 (KRG72_08895)	-	1797324..1797677 (-)	354	WP_258255169.1	YlbF family regulator	-
KRG72_RS08900 (KRG72_08900)	argR	1797674..1798111 (-)	438	WP_006531423.1	arginine repressor	-
KRG72_RS08905 (KRG72_08905)	argS	1798301..1799992 (+)	1692	WP_157629471.1	arginine--tRNA ligase	-
KRG72_RS08910 (KRG72_08910)	-	1800107..1800400 (+)	294	WP_258255171.1	bacteriocin immunity protein	-
KRG72_RS08915 (KRG72_08915)	-	1800429..1801844 (-)	1416	WP_258255172.1	prolyl oligopeptidase family serine peptidase	-

Sequence

Protein

• Length: 855 a.a.
• Molecular weight: 95961.08 Da
• Isoelectric Point: 4.8320

>NTDB_id=504109 KRG72_RS08890 WP_258255168.1 1794770..1797337(-) (hexA) [Streptococcus equinus strain S1]
MAKDKISPGMQQYLDVKKDYPDAFLLFRMGDFYELFYEDAVKAAQILEISLTSRNKNADNPIPMAGVPYHSAQQYIDVLV
EMGYKVAIAEQMEDPKQAVGVVKREVVQVITPGTAVDSSKPDNANNFLVAIDSDGKNFGLAYMDVSTGEFYATSLSDFTS
LKSEILNLKAREIVVGYDLSEDEQHSLVKQLNLLLSFEQERYEDVHLIDPNLTALEISAAEKLLQYVHTTQKRELSHLQK
LVHYEIKDYLQMSYTTKSSLDLLENARTSKKHGSLYWLLDETKTAMGMRLLRNWIDRPLVNQEQIEERQNIVQVFLDNFF
ERSDLTDSLKGVYDIERLASRVSFGKANPKDLLQLGHTLGQVPTIKAILESFDSPYLDKLVNSIDTLPELESLISSAIDP
DAQAVITEGSIIRTGFDETLDKYRKVMREGTSWIAEIEAKERAASGITNLKIDYNKKDGYYFHVTNSNLSLVPDYFFRKA
TLKNSERFGTAELAKIEGEMLEAREQSASLEYDIFMRVRAQVERYISRLQDLAKAISTVDVLQSLAVVAENNHYVRPSFN
DSHEIKIEKGRHAVVEKVMGTQEYIPNTITFGRNTNIQLITGPNMSGKSTYMRQLALTVIMAQMGSYVAAESVSLPVFDA
IFTRIGAADDLISGQSTFMVEMMEANQAIKRASEKSLILFDELGRGTATYDGMALAQSIIEYIHDHIGAKTMFATHYHEL
TSLSTTLTHLVNVHVATLERNGDVTFLHKIAEGPADKSYGIHVAKIAGLPEDLLQRADSILTNLESGAAQLHLTAETEEK
TQVKIEAAEPVAEQLSLFADDSSNQEVIEALKKVDLMNLTPMQAMNVIYELKNML

Nucleotide

• Length: 2568 bp

>NTDB_id=504109 KRG72_RS08890 WP_258255168.1 1794770..1797337(-) (hexA) [Streptococcus equinus strain S1]
ATGGCAAAAGATAAAATTTCTCCAGGCATGCAACAGTATTTGGATGTCAAAAAAGACTATCCAGATGCTTTTTTACTTTT
CCGCATGGGAGACTTTTACGAACTATTTTATGAGGATGCCGTTAAGGCGGCACAGATTTTAGAGATTAGTTTAACTAGTC
GTAATAAAAATGCTGACAATCCTATTCCGATGGCTGGTGTTCCTTATCATTCAGCCCAACAATACATTGATGTCTTAGTT
GAGATGGGGTATAAGGTTGCCATTGCTGAGCAGATGGAAGATCCGAAGCAGGCAGTGGGCGTGGTTAAGCGTGAAGTCGT
TCAGGTGATTACACCAGGGACAGCGGTTGATTCTTCTAAGCCAGATAATGCTAATAATTTCTTGGTAGCTATTGATTCTG
ATGGCAAAAACTTTGGTTTGGCTTATATGGATGTGTCAACGGGTGAGTTTTACGCGACAAGTTTGTCTGATTTTACAAGC
CTAAAAAGTGAGATTTTAAACCTCAAGGCTCGTGAAATCGTGGTTGGTTATGACCTTTCTGAAGATGAGCAACACAGCTT
GGTTAAACAACTCAATCTCTTATTATCGTTTGAGCAAGAGCGCTATGAAGATGTGCATTTGATTGACCCGAATTTAACAG
CGTTAGAGATTTCTGCTGCTGAAAAATTACTTCAATACGTTCATACGACACAAAAACGTGAACTTAGTCACCTGCAAAAG
CTGGTTCACTATGAAATCAAAGACTATCTTCAAATGTCTTATACGACAAAATCAAGTCTTGATTTGCTAGAAAATGCCCG
CACAAGCAAGAAGCACGGTAGTCTTTACTGGTTGCTTGATGAAACTAAGACGGCTATGGGAATGCGTTTGTTGCGTAACT
GGATTGATCGTCCATTGGTTAATCAAGAACAAATTGAAGAACGCCAAAATATTGTCCAAGTTTTCTTAGACAACTTCTTT
GAACGTAGTGATTTGACGGACAGTCTAAAAGGCGTTTATGATATTGAGCGTTTGGCTAGTCGTGTGTCATTTGGAAAAGC
CAATCCAAAAGATTTGCTTCAACTTGGTCACACTTTGGGACAAGTGCCAACTATTAAAGCTATCTTGGAATCTTTTGATA
GTCCTTACCTTGACAAGCTTGTCAACAGCATTGACACTTTACCAGAGCTAGAGTCATTGATTAGCTCTGCTATTGACCCA
GATGCTCAAGCAGTGATTACGGAAGGAAGTATTATCAGAACTGGTTTTGATGAGACTTTGGACAAATATCGTAAAGTCAT
GCGCGAAGGGACAAGCTGGATTGCTGAGATTGAAGCCAAAGAACGTGCAGCAAGTGGTATTACAAACCTAAAAATTGATT
ACAATAAAAAAGATGGTTACTATTTCCATGTAACAAATTCTAACCTTTCTTTGGTGCCAGATTACTTCTTCCGTAAAGCA
ACTTTGAAGAATTCAGAGCGTTTTGGTACGGCAGAATTAGCTAAAATTGAAGGTGAAATGCTTGAGGCGCGTGAGCAATC
AGCGAGTCTGGAATACGATATTTTCATGCGCGTTCGCGCACAGGTGGAACGTTATATTTCACGTCTGCAAGATTTGGCAA
AAGCTATTTCTACAGTCGATGTTCTGCAAAGTTTGGCAGTGGTTGCGGAAAACAACCATTATGTTCGTCCAAGCTTTAAT
GATAGCCATGAAATTAAGATTGAAAAAGGTCGCCATGCGGTTGTTGAAAAAGTCATGGGTACGCAAGAATATATCCCAAA
TACCATCACATTTGGCAGAAATACCAATATTCAGCTGATTACTGGTCCAAATATGAGTGGTAAGTCAACTTATATGCGTC
AGTTAGCTTTGACGGTTATCATGGCGCAGATGGGGTCATATGTTGCTGCTGAGAGTGTCAGTCTTCCCGTTTTTGATGCG
ATTTTCACACGTATCGGTGCGGCGGATGATTTGATTTCAGGTCAATCAACCTTTATGGTGGAAATGATGGAAGCCAACCA
AGCCATCAAACGTGCCAGTGAAAAATCTCTGATTCTCTTTGATGAATTGGGACGCGGGACAGCGACTTACGATGGAATGG
CTTTAGCGCAATCTATCATTGAGTATATCCACGATCACATTGGTGCTAAGACCATGTTTGCGACTCACTATCATGAGTTG
ACATCTCTGTCAACTACCTTGACACATCTTGTAAACGTCCATGTTGCAACGCTTGAACGTAATGGTGATGTGACTTTCCT
TCATAAAATCGCAGAAGGACCAGCTGACAAATCTTATGGTATTCATGTTGCGAAAATTGCAGGTTTGCCAGAAGATTTGT
TGCAACGAGCAGATAGTATTTTAACCAATCTCGAATCAGGTGCTGCGCAGCTTCATTTGACAGCAGAAACTGAAGAGAAA
ACTCAAGTGAAGATAGAAGCGGCAGAACCTGTTGCAGAGCAGCTTAGCTTATTTGCAGATGACTCAAGTAACCAAGAAGT
GATTGAAGCTCTTAAAAAAGTGGACTTGATGAATCTAACACCAATGCAAGCTATGAATGTCATTTATGAATTGAAAAACA
TGTTATAA

Domains

Predicted by InterProScan.

• MutS domain I (MutS_I) (8-118)

• MutS domain III (MutS_III) (256-546)

• MutS domain V (MutS_V) (599-785)

• MutS family domain IV (MutS_IV) (415-505)

• MutS domain II (MutS_II) (126-239)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	73.099	100	0.731
mutS	Pseudomonas stutzeri strain ATCC 17587	37.342	100	0.381