Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   KRG72_RS08885 Genome accession   NZ_CP076703
Coordinates   1792710..1794650 (-) Length   646 a.a.
NCBI ID   WP_258255164.1    Uniprot ID   -
Organism   Streptococcus equinus strain S1     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1787710..1799650
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KRG72_RS08865 (KRG72_08865) cinA 1788763..1790022 (-) 1260 WP_258255159.1 competence/damage-inducible protein A Machinery gene
  KRG72_RS08870 (KRG72_08870) - 1790151..1791332 (-) 1182 WP_258255160.1 MFS transporter -
  KRG72_RS08875 (KRG72_08875) - 1791535..1792086 (-) 552 WP_258255161.1 DNA-3-methyladenine glycosylase I -
  KRG72_RS08880 (KRG72_08880) ruvA 1792116..1792709 (-) 594 WP_074869549.1 Holliday junction branch migration protein RuvA Machinery gene
  KRG72_RS08885 (KRG72_08885) hexB 1792710..1794650 (-) 1941 WP_258255164.1 DNA mismatch repair endonuclease MutL Machinery gene
  KRG72_RS08890 (KRG72_08890) hexA 1794770..1797337 (-) 2568 WP_258255168.1 DNA mismatch repair protein MutS Machinery gene
  KRG72_RS08895 (KRG72_08895) - 1797324..1797677 (-) 354 WP_258255169.1 YlbF family regulator -
  KRG72_RS08900 (KRG72_08900) argR 1797674..1798111 (-) 438 WP_006531423.1 arginine repressor -

Sequence

Protein


Download         Length: 646 a.a.        Molecular weight: 73163.21 Da        Isoelectric Point: 5.2904

>NTDB_id=504108 KRG72_RS08885 WP_258255164.1 1792710..1794650(-) (hexB) [Streptococcus equinus strain S1]
MSKIIELPEVLANQIAAGEVIERPASVVKELVENSIDAGSSQITIEIEESGLKRIQVTDNGEGISQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADEHYGTLLVAKGGEIERQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGRQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEVRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGFSKPQQTSLPLKQTNLYYDKERHDFFVKSDTVEEEPAQLFNEVDKAVKQVDKQS
SVRYAQRSAAGQAYDEHDDLDFKNKTKINRMIESLDNEEVSTFPELEYFGQMHGTYLFAQGDGGLYIIDQHAAQERVKYE
YYRDKIGEVDDSLQQLLMPYLFEFSGADFIKIQEKMELLNQVGINLEPYGNNTFILREHPIWMKEEEIETAVYEMCDMLL
LTNEVSVKKYRAELAIMMSCKRSIKANHTLDDYSARQLIVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSL
RELGKY

Nucleotide


Download         Length: 1941 bp        

>NTDB_id=504108 KRG72_RS08885 WP_258255164.1 1792710..1794650(-) (hexB) [Streptococcus equinus strain S1]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCCAACCAGATTGCTGCAGGTGAAGTGATTGAACGACCGGCCAGTGT
GGTTAAAGAATTGGTTGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACCATCGAGATTGAAGAATCAGGTCTTAAGA
GGATTCAAGTCACTGATAATGGTGAGGGAATTTCTCAAGAGGATGTGGCTTTAAGTTTGCATCGCCATGCTACCAGCAAG
ATTAAAAGCCAAGCTGATCTTTTTCGTATCAGAACTTTGGGATTCCGCGGTGAGGCCATTCCTTCCATTGCCTCAATTAG
CCACTTTACAGTGAAAACAGCGACAGCTGATGAACACTATGGAACGCTTTTAGTGGCAAAGGGGGGCGAGATTGAGCGAC
AAGAACCAATTTCAACACCTGTCGGGACAAAAATTACTGTTGAAAATCTTTTTTACAACACACCTGCTCGTCTCAAATAT
ATGAAGAGCTTGCAATCAGAGTTGGCTCATATCGTTGATGTGGTTAATCGCTTGAGCCTAGCTCACCCAGAAATTGCCTT
TACTTTGATTAATGATGGTCGTCAAATGACAACGACTTCTGGGACAGGAGATTTGCGCCAAGCCATCGCTGGTATTTATG
GTTTAAATACAGCTAAGAAAATGATTGAGATTTCGAATGCTGATCTTGATTTTGAAGTCTCAGGTTATATTAGCTTGCCA
GAATTGACGCGTGCAAATCGCAATTACATCACCATTTTAATCAATGGTCGTTACATTAAAAACTTTTTGCTTAATCGTGC
TATTTTAGATGGCTACGGTTCAAAATTGATGGTTGGGCGTTTTCCGATTGCTGTCATTGACATTCAAATCGACCCTTATC
TTGCCGATGTCAATGTTCACCCAACTAAACAAGAAGTTCGTATCTCAAAAGAAAAAGAACTCATGAGCTTAATTAGCTCA
GCTATTGCAGAGAGTTTGCGTGAGCAAGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGTACTCGAGGTTT
TTCAAAACCTCAGCAAACGAGTCTGCCTTTAAAACAAACCAACCTTTACTATGATAAGGAACGTCACGATTTCTTTGTGA
AATCAGATACGGTTGAAGAAGAGCCAGCGCAGTTATTTAATGAGGTTGACAAAGCTGTCAAGCAAGTTGACAAGCAATCT
TCAGTTAGGTATGCACAGCGTTCGGCGGCAGGTCAAGCGTATGATGAGCATGATGATCTTGATTTTAAAAATAAAACGAA
AATCAATCGCATGATTGAAAGTCTTGATAATGAGGAAGTCTCTACTTTCCCTGAGTTAGAGTACTTTGGGCAAATGCACG
GCACTTATCTTTTTGCGCAAGGTGATGGTGGGCTTTATATCATTGACCAGCATGCGGCTCAGGAACGTGTCAAGTATGAG
TATTATCGTGACAAAATTGGCGAAGTTGATGATTCATTACAACAGTTGCTAATGCCATATCTATTTGAGTTTTCTGGGGC
AGATTTCATCAAAATTCAAGAAAAAATGGAGCTTCTAAATCAAGTTGGCATTAATTTAGAACCATACGGCAATAACACTT
TTATCCTTCGCGAGCATCCTATTTGGATGAAGGAAGAGGAGATTGAGACAGCTGTTTATGAAATGTGCGACATGTTGCTG
TTGACCAATGAAGTTTCTGTCAAGAAATACCGTGCTGAGTTAGCGATTATGATGTCATGTAAACGATCAATCAAGGCTAA
CCATACCCTTGATGACTATTCAGCCCGACAACTCATTGTTCAATTATCTCAATGTAAGAACCCTTATAACTGCCCACACG
GACGTCCAGTACTTGTTAATTTTACCAAGTCAGACATGGAAAAAATGTTCCGTCGTATTCAAGAAAATCACACAAGTTTA
AGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-118)

MutL C terminal dimerisation domain (MutL_C)

(448-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

70.076

100

0.711