Detailed information NTG0504100

Bioinformatically predicted

Overview

• Name: comE/comE1
• Type: Regulator
• Locus tag: KRG72_RS08275
• Genome accession: NZ_CP076703
• Coordinates: 1668265..1668996 (-)
• Length: 243 a.a.
• NCBI ID: WP_258254926.1
• Uniprot ID: -
• Organism: Streptococcus equinus strain S1
• Function: activate transcription of early competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1663265..1673996

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
KRG72_RS08245 (KRG72_08255)	-	1664115..1664408 (-)	294	WP_205395459.1	bacteriocin immunity protein	-
KRG72_RS08250 (KRG72_08260)	-	1664436..1664741 (-)	306	WP_133018012.1	bacteriocin immunity protein	-
KRG72_RS08255 (KRG72_08265)	-	1664754..1664903 (-)	150	WP_039696228.1	hypothetical protein	-
KRG72_RS08260 (KRG72_08270)	comD/comD1	1665147..1666457 (-)	1311	WP_258254918.1	sensor histidine kinase	Regulator
KRG72_RS08265 (KRG72_08275)	comC/comC1	1666772..1666915 (+)	144	WP_160172983.1	hypothetical protein	Regulator
KRG72_RS08270 (KRG72_08280)	comD/comD1	1666938..1668260 (-)	1323	WP_074799079.1	sensor histidine kinase	Regulator
KRG72_RS08275 (KRG72_08285)	comE/comE1	1668265..1668996 (-)	732	WP_258254926.1	response regulator transcription factor	Regulator
KRG72_RS08280 (KRG72_08290)	-	1670027..1671319 (-)	1293	WP_258254929.1	glycosyltransferase family 2 protein	-
KRG72_RS08285 (KRG72_08295)	-	1671322..1671621 (-)	300	WP_157327346.1	DUF3884 family protein	-
KRG72_RS08290 (KRG72_08300)	-	1671647..1671829 (-)	183	WP_157327348.1	hypothetical protein	-
KRG72_RS08295 (KRG72_08305)	-	1671895..1672119 (-)	225	WP_039697856.1	helix-turn-helix domain-containing protein	-
KRG72_RS08300 (KRG72_08310)	-	1672109..1673107 (-)	999	WP_258254932.1	thioredoxin family protein	-
KRG72_RS08305 (KRG72_08315)	-	1673367..1673576 (-)	210	WP_258254933.1	hypothetical protein	-
KRG72_RS08310 (KRG72_08320)	-	1673617..1673781 (-)	165	WP_258254936.1	Blp family class II bacteriocin	-

Sequence

Protein

• Length: 243 a.a.
• Molecular weight: 28198.10 Da
• Isoelectric Point: 6.2472

>NTDB_id=504100 KRG72_RS08275 WP_258254926.1 1668265..1668996(-) (comE/comE1) [Streptococcus equinus strain S1]
MLDIFILEDNITQQFRIERQIETIMERNHWEYQRLEAFAASKDIIKKADGQGNHQVFFLDLEIKGDEKQGLDVARSIREK
DPTAIIVFVTTHSEFMLLTYQSLVGAIDFIDKNMNDEAFGGRIELCLKEALKYQTGSFGENSYLFETTKARIRVAYDDIL
YFETSPTVHRVILHTKTGQTEFYGTIAEVAKSDKRLLKCHRSFVINVNNVTEFDKSTRTAYFENGSYCQVSRDKVKKLMA
EMR

Nucleotide

• Length: 732 bp

>NTDB_id=504100 KRG72_RS08275 WP_258254926.1 1668265..1668996(-) (comE/comE1) [Streptococcus equinus strain S1]
ATGTTAGATATTTTTATCCTTGAGGATAATATCACGCAACAATTTCGAATCGAACGTCAGATTGAGACGATTATGGAAAG
GAACCACTGGGAGTATCAGCGTTTAGAGGCTTTTGCGGCATCTAAGGATATTATAAAAAAGGCAGATGGGCAGGGAAATC
ACCAGGTTTTCTTTCTTGATTTAGAAATCAAAGGGGATGAAAAGCAAGGCTTAGATGTTGCTAGATCTATTCGTGAAAAA
GATCCGACAGCCATTATCGTCTTTGTGACAACCCATTCTGAATTTATGCTGCTAACTTACCAATCTTTAGTTGGTGCAAT
TGATTTTATTGATAAAAATATGAATGATGAAGCCTTTGGAGGGCGCATTGAATTGTGCTTGAAAGAGGCATTGAAATATC
AAACTGGTAGTTTTGGTGAGAATTCTTACCTGTTTGAAACAACAAAAGCAAGAATCCGTGTAGCTTATGATGATATTTTA
TATTTTGAAACATCGCCAACCGTGCACCGTGTGATTTTACACACTAAAACAGGTCAAACAGAGTTTTATGGCACAATCGC
TGAGGTAGCCAAATCAGATAAACGTTTGTTGAAATGTCACCGCTCATTCGTGATTAATGTTAATAATGTCACTGAATTTG
ATAAAAGCACCCGAACAGCTTATTTCGAAAACGGCTCTTACTGCCAAGTCTCAAGAGACAAAGTTAAAAAACTGATGGCA
GAAATGAGGTGA

Domains

Predicted by InterProScan.

• LytTr DNA-binding domain (LytTR) (152-240)

• Response regulator receiver domain (Response_reg) (4-118)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE/comE1	Streptococcus equinus JB1	99.588	100	0.996
comE/blpR	Streptococcus mutans UA159	46.888	99.177	0.465
comE/comE2	Streptococcus equinus JB1	45.041	99.588	0.449