Detailed information    

insolico Bioinformatically predicted

Overview

Name   crp   Type   Regulator
Locus tag   KQ259_RS18320 Genome accession   NZ_CP076697
Coordinates   3731821..3732453 (+) Length   210 a.a.
NCBI ID   WP_000242755.1    Uniprot ID   A0A1C4FZU4
Organism   Escherichia coli strain S10EC     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3726821..3737453
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KQ259_RS18295 (KQ259_18295) yheS 3726990..3728903 (+) 1914 WP_000634830.1 ABC transporter ATP-binding protein -
  KQ259_RS18300 (KQ259_18300) yheT 3728903..3729925 (+) 1023 WP_000057364.1 hydrolase -
  KQ259_RS18305 (KQ259_18305) yheU 3729919..3730137 (+) 219 WP_000907085.1 YheU family protein -
  KQ259_RS18310 (KQ259_18310) prkB 3730191..3731060 (+) 870 WP_001274684.1 phosphoribulokinase -
  KQ259_RS18315 (KQ259_18315) yhfA 3731115..3731519 (-) 405 WP_001148908.1 OsmC family protein -
  KQ259_RS18320 (KQ259_18320) crp 3731821..3732453 (+) 633 WP_000242755.1 cAMP-activated global transcriptional regulator CRP Regulator
  KQ259_RS18325 (KQ259_18325) yhfK 3732504..3734594 (+) 2091 WP_001296470.1 YccS/YhfK family putative transporter -
  KQ259_RS18330 (KQ259_18330) argD 3734661..3735881 (-) 1221 WP_000963794.1 bifunctional acetylornithine/succinyldiaminopimelate transaminase -
  KQ259_RS18335 (KQ259_18335) pabA 3735967..3736530 (-) 564 WP_000601853.1 aminodeoxychorismate synthase component 2 -
  KQ259_RS18340 (KQ259_18340) fic 3736562..3737164 (-) 603 WP_001280613.1 putative adenosine monophosphate-protein transferase Fic -
  KQ259_RS18345 (KQ259_18345) yhfG 3737154..3737321 (-) 168 WP_000736858.1 YhfG family protein -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23640.43 Da        Isoelectric Point: 8.2710

>NTDB_id=503972 KQ259_RS18320 WP_000242755.1 3731821..3732453(+) (crp) [Escherichia coli strain S10EC]
MVLGKPQTDPTLEWFLSHCHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG
QERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGRIAQTLLNLAKQPDAMTH
PDGMQIKITRQEIGQIVGCSRETVGRILKMLEDQNLISAHGKTIVVYGTR

Nucleotide


Download         Length: 633 bp        

>NTDB_id=503972 KQ259_RS18320 WP_000242755.1 3731821..3732453(+) (crp) [Escherichia coli strain S10EC]
ATGGTGCTTGGCAAACCGCAAACAGACCCGACTCTCGAATGGTTCTTGTCTCATTGCCACATTCATAAGTACCCATCCAA
GAGCACGCTTATTCACCAGGGTGAAAAAGCGGAAACGCTGTACTACATCGTTAAAGGCTCTGTGGCAGTGCTGATCAAAG
ACGAAGAGGGTAAAGAAATGATCCTCTCCTATCTGAATCAGGGTGATTTTATTGGCGAACTGGGCCTGTTTGAAGAGGGC
CAGGAACGTAGCGCATGGGTACGTGCGAAAACCGCCTGTGAAGTGGCTGAAATTTCGTACAAAAAATTTCGCCAATTGAT
TCAGGTAAACCCGGACATTCTGATGCGTCTGTCTGCACAGATGGCGCGTCGTCTGCAAGTCACTTCAGAGAAAGTGGGCA
ACCTGGCGTTCCTCGACGTGACGGGCCGCATTGCACAGACTCTGCTGAATCTGGCAAAACAACCGGATGCTATGACTCAC
CCGGACGGTATGCAAATCAAAATTACCCGTCAGGAAATCGGTCAGATTGTCGGCTGTTCTCGTGAAACCGTGGGACGCAT
TCTGAAGATGCTGGAAGATCAGAACCTGATCTCCGCACACGGTAAAACCATCGTCGTTTACGGCACTCGTTAA

Domains

Predicted by InterProScan.

Cyclic nucleotide-binding domain (cNMP_binding)

(23-109)

Crp-like helix-turn-helix domain (HTH_Crp_2)

(142-206)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1C4FZU4

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  crp Vibrio cholerae strain A1552

95.714

100

0.957
  crp Haemophilus influenzae Rd KW20

77.941

97.143

0.757
  crp Acinetobacter baumannii D1279779

47.343

98.571

0.467