Detailed information    

insolico Bioinformatically predicted

Overview

Name   ciaH   Type   Regulator
Locus tag   KPA27_RS04505 Genome accession   NZ_CP076517
Coordinates   873110..874489 (+) Length   459 a.a.
NCBI ID   WP_024401460.1    Uniprot ID   -
Organism   Streptococcus suis strain 39565     
Function   repress competence development; post-transcriptional repression of CSP production (predicted from homology)   
Competence regulation

Genomic Context

Location: 868110..879489
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KPA27_RS04475 (KPA27_04475) pstA 868536..869423 (+) 888 WP_002937616.1 phosphate ABC transporter permease PstA -
  KPA27_RS04480 (KPA27_04480) pstB 869448..870251 (+) 804 WP_002937615.1 phosphate ABC transporter ATP-binding protein PstB -
  KPA27_RS04485 (KPA27_04485) pstB 870263..871021 (+) 759 WP_002937614.1 phosphate ABC transporter ATP-binding protein PstB -
  KPA27_RS04490 (KPA27_04490) phoU 871050..871706 (+) 657 WP_002937611.1 phosphate signaling complex protein PhoU -
  KPA27_RS04495 (KPA27_04495) - 871872..872252 (+) 381 WP_024401461.1 hypothetical protein -
  KPA27_RS04500 (KPA27_04500) ciaR 872446..873117 (+) 672 WP_014637852.1 response regulator transcription factor Regulator
  KPA27_RS04505 (KPA27_04505) ciaH 873110..874489 (+) 1380 WP_024401460.1 HAMP domain-containing sensor histidine kinase Regulator
  KPA27_RS04510 (KPA27_04510) - 874590..875819 (+) 1230 WP_216330890.1 transglutaminase domain-containing protein -
  KPA27_RS04515 (KPA27_04515) rpsT 876034..876282 (-) 249 WP_012027069.1 30S ribosomal protein S20 -
  KPA27_RS04520 (KPA27_04520) coaA 876341..877261 (-) 921 WP_024410470.1 type I pantothenate kinase -
  KPA27_RS04525 (KPA27_04525) - 877370..877960 (+) 591 WP_024376492.1 class I SAM-dependent methyltransferase -
  KPA27_RS04530 (KPA27_04530) - 877957..879234 (+) 1278 WP_044680727.1 pyrimidine-nucleoside phosphorylase -

Sequence

Protein


Download         Length: 459 a.a.        Molecular weight: 51862.42 Da        Isoelectric Point: 5.8702

>NTDB_id=503154 KPA27_RS04505 WP_024401460.1 873110..874489(+) (ciaH) [Streptococcus suis strain 39565]
MPKRIGKLVYTDKFSFFIRYFAVFTLIFGLMTAIIFQLMRSTMYQNSDNTLKRIKEEPAMAVGFAIARTYEPNSVFILQD
SPTSEETTSSSSDSMPVPKDQKNTRDGDQLRLGVNTHVLLYSKSGEMVNPDTFTGLADLPLDKEKLGEIKETTVESSFGM
SEDYRYVTIELATDELGYYSSYDIKYATILVNVSQIKSSIETYESTVAIVMVSAWLISILASIYLSNLSMRPILISYQKQ
KDFVENASHELRTPLAVLQNRLESLFRHPEATILESSESIGSSLEEVRNMRLLTTNLLNLARRDDGLKVDMIDVQPNYFD
EIFANYLMIAEENGKTLTVNNLIHQPIRTDKVLIKQLLTILFDNAMKYTDDDGRIQITANIKDKSVYFTVADNGLGISDA
DKKKIFDRFYRVDKARTRQKGGFGLGLSLAQQIIKTLGGKISVRDNQPKGTIFEVGLPK

Nucleotide


Download         Length: 1380 bp        

>NTDB_id=503154 KPA27_RS04505 WP_024401460.1 873110..874489(+) (ciaH) [Streptococcus suis strain 39565]
ATGCCTAAGCGAATCGGAAAATTAGTGTATACGGATAAATTTTCCTTCTTTATCCGTTATTTTGCAGTATTTACCCTGAT
TTTTGGCTTGATGACAGCTATCATTTTTCAATTAATGCGTTCAACTATGTATCAAAATTCAGATAATACCTTGAAACGGA
TTAAGGAAGAACCAGCGATGGCTGTTGGTTTTGCGATCGCAAGAACCTATGAGCCCAACTCTGTCTTTATACTTCAAGAT
AGCCCAACTAGTGAAGAAACGACGAGCTCTAGCTCAGATAGCATGCCTGTTCCTAAAGATCAAAAAAATACTAGAGATGG
AGATCAGCTGAGATTAGGTGTCAATACTCATGTCTTACTCTATAGTAAAAGTGGAGAAATGGTCAATCCGGATACTTTTA
CTGGTTTGGCCGACCTACCGTTAGATAAGGAAAAATTGGGCGAAATTAAGGAAACAACGGTTGAATCAAGCTTCGGTATG
TCTGAAGATTATCGCTATGTGACGATTGAGCTTGCTACAGATGAACTAGGTTATTATTCGTCCTATGATATAAAATATGC
GACAATTTTAGTGAATGTCAGCCAAATAAAATCCTCCATTGAGACCTATGAATCGACAGTTGCTATTGTTATGGTATCAG
CTTGGCTCATTTCTATCTTGGCCAGTATTTACCTATCAAATCTTAGCATGCGTCCAATTCTAATCAGTTATCAAAAGCAA
AAAGACTTTGTTGAAAATGCTAGTCATGAGTTACGTACGCCGTTGGCTGTTCTCCAAAATCGCTTGGAGAGCCTGTTTCG
CCATCCCGAAGCGACGATTTTAGAGAGTAGTGAAAGTATCGGATCTAGTTTAGAAGAAGTCCGAAATATGCGATTATTGA
CAACGAACCTGCTCAATTTGGCTCGTCGTGATGATGGCTTAAAAGTCGATATGATCGATGTCCAACCCAACTATTTTGAT
GAAATCTTTGCTAATTACCTTATGATTGCCGAAGAAAATGGAAAAACACTGACAGTTAATAATTTGATTCATCAGCCGAT
TCGAACAGACAAGGTCCTTATTAAACAGTTGCTTACCATTTTATTTGACAATGCCATGAAGTATACCGATGATGATGGCA
GAATTCAAATTACAGCTAATATCAAGGATAAATCTGTCTACTTCACAGTTGCCGACAATGGTTTGGGAATCAGCGATGCC
GATAAGAAGAAAATCTTTGATCGCTTTTATCGAGTTGATAAGGCCAGAACGCGTCAAAAAGGTGGTTTCGGTCTAGGATT
ATCGCTGGCTCAGCAAATTATTAAGACACTAGGTGGGAAAATCTCTGTTAGAGATAACCAACCGAAAGGAACTATTTTTG
AGGTAGGATTACCTAAATAA

Domains

Predicted by InterProScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(240-306)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(350-458)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ciaH Streptococcus pneumoniae Rx1

49.46

100

0.499
  ciaH Streptococcus pneumoniae D39

49.46

100

0.499
  ciaH Streptococcus pneumoniae R6

49.46

100

0.499
  ciaH Streptococcus pneumoniae TIGR4

49.46

100

0.499
  ciaH Streptococcus mutans UA159

50.336

97.386

0.49