Detailed information    

insolico Bioinformatically predicted

Overview

Name   agrA   Type   Regulator
Locus tag   HWI59_RS04280 Genome accession   NZ_CP064471
Coordinates   916950..917666 (-) Length   238 a.a.
NCBI ID   WP_002447515.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain UMCG387     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 911950..922666
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  HWI59_RS04265 (HWI59_04225) - 913231..914184 (+) 954 WP_020363477.1 LacI family DNA-binding transcriptional regulator -
  HWI59_RS04270 (HWI59_04230) - 914444..915916 (+) 1473 WP_020363476.1 sucrose-6-phosphate hydrolase -
  HWI59_RS04275 (HWI59_04235) - 915923..916882 (+) 960 WP_002457913.1 carbohydrate kinase -
  HWI59_RS04280 (HWI59_04240) agrA 916950..917666 (-) 717 WP_002447515.1 quorum-sensing response regulator AgrA Regulator
  HWI59_RS04285 (HWI59_04245) agrC 917683..918972 (-) 1290 WP_162154632.1 quorum-sensing sensor histidine kinase AgrC -
  HWI59_RS04290 (HWI59_04250) agrD 918997..919137 (-) 141 WP_002487333.1 cyclic lactone autoinducer peptide AgrD -
  HWI59_RS04295 (HWI59_04255) - 919143..919706 (-) 564 WP_237618395.1 accessory gene regulator B family protein -
  HWI59_RS04300 (HWI59_04260) hld 920023..920100 (+) 78 WP_002494082.1 delta-hemolysin -
  HWI59_RS04305 (HWI59_04265) - 920481..921266 (-) 786 WP_237618394.1 carbon-nitrogen family hydrolase -

Sequence

Protein


Download         Length: 238 a.a.        Molecular weight: 27967.00 Da        Isoelectric Point: 5.6250

>NTDB_id=502155 HWI59_RS04280 WP_002447515.1 916950..917666(-) (agrA) [Staphylococcus epidermidis strain UMCG387]
MKIFVCEDDQRQREHMVSIIKNYIMIEEKPMELTLATNDPYEVLEQSKELNDIGCYFLDIQLEADMNGIKLASEIRKHDP
VGNIIFVTSHSELTYLTFVYKVAAMDFIFKDDPSELKMRIIDCLETAHTRLKLLSKESNVDTIELKRGSNSVYVQYDDIM
FFESSTKSHRLIAHLDNRQIEFYGNLKELAQLDERFFRCHNSFVINRHNIESIDSKERIVYFKNGENCFASVRNVKKI

Nucleotide


Download         Length: 717 bp        

>NTDB_id=502155 HWI59_RS04280 WP_002447515.1 916950..917666(-) (agrA) [Staphylococcus epidermidis strain UMCG387]
ATGAAAATTTTTGTTTGTGAAGATGACCAAAGACAAAGAGAACATATGGTATCAATCATTAAAAACTACATAATGATTGA
AGAAAAGCCAATGGAGTTAACTTTAGCAACAAATGATCCTTATGAGGTTTTAGAGCAATCAAAAGAACTTAATGACATTG
GTTGTTACTTCCTTGATATTCAATTAGAAGCTGATATGAACGGTATTAAATTAGCCAGTGAAATTCGTAAACATGATCCT
GTTGGTAATATTATATTTGTAACCAGTCACAGTGAACTGACTTATTTGACATTTGTTTATAAAGTGGCTGCTATGGATTT
TATTTTTAAGGATGATCCATCTGAATTAAAAATGAGAATCATAGATTGTCTTGAAACAGCACATACACGACTCAAATTAT
TATCTAAAGAAAGTAATGTAGATACGATTGAGTTAAAACGTGGAAGTAATTCAGTATACGTTCAATATGATGATATTATG
TTTTTTGAATCATCTACGAAATCTCATAGACTCATCGCACATCTTGATAATCGACAAATTGAATTTTATGGAAATTTAAA
GGAATTAGCACAGCTTGATGAACGTTTCTTTAGATGTCATAACAGTTTTGTAATAAACAGACATAATATTGAATCTATTG
ATTCAAAAGAACGTATTGTTTACTTTAAGAATGGCGAAAATTGTTTCGCTTCAGTACGTAATGTTAAAAAAATATAA

Domains

Predicted by InterproScan.

LytTr DNA-binding domain (LytTR)

(151-237)

Response regulator receiver domain (Response_reg)

(3-120)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  agrA Staphylococcus aureus N315

87.395

100

0.874
  comE/comE2 Streptococcus gordonii strain NCTC7865

35.178

100

0.374
  comE/comE1 Streptococcus gordonii str. Challis substr. CH1

35.178

100

0.374