Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   KE3_RS09500 Genome accession   NC_021900
Coordinates   1890989..1892929 (-) Length   646 a.a.
NCBI ID   WP_020917598.1    Uniprot ID   A0AB33APE8
Organism   Streptococcus lutetiensis 033     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1885989..1897929
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KE3_RS09480 (KE3_1958) cinA 1887043..1888302 (-) 1260 WP_020917595.1 competence/damage-inducible protein A Machinery gene
  KE3_RS09485 - 1888431..1889360 (-) 930 WP_228380499.1 MFS transporter -
  KE3_RS11065 - 1889386..1889613 (-) 228 WP_228380500.1 MFS transporter -
  KE3_RS09490 (KE3_1959) - 1889814..1890365 (-) 552 WP_043895144.1 DNA-3-methyladenine glycosylase I -
  KE3_RS09495 (KE3_1960) ruvA 1890395..1890988 (-) 594 WP_020917597.1 Holliday junction branch migration protein RuvA Machinery gene
  KE3_RS09500 (KE3_1961) hexB 1890989..1892929 (-) 1941 WP_020917598.1 DNA mismatch repair endonuclease MutL Machinery gene
  KE3_RS09505 (KE3_1962) hexA 1893049..1895616 (-) 2568 WP_020917599.1 DNA mismatch repair protein MutS Machinery gene
  KE3_RS09510 (KE3_1963) - 1895603..1895956 (-) 354 WP_020917600.1 YlbF family regulator -
  KE3_RS09515 (KE3_1964) argR 1895953..1896390 (-) 438 WP_020917601.1 arginine repressor -

Sequence

Protein


Download         Length: 646 a.a.        Molecular weight: 73143.38 Da        Isoelectric Point: 5.3658

>NTDB_id=50089 KE3_RS09500 WP_020917598.1 1890989..1892929(-) (hexB) [Streptococcus lutetiensis 033]
MSKIIELPEVLANQIAAGEVVERPASVVKELVENSIDAGSSQITIEIEESGLKKIQVTDNGEGISQEDVALSLHRHATSK
IKSQADLFRIRTLGFRGEAIPSIASISHFTVKTATADEHYGMLLVAKGGEIERQEPISTPVGTKITVENLFYNTPARLKY
MKSLQSELAHIVDVVNRLSLAHPEIAFTLINDGHQMTTTSGTGDLRQAIAGIYGLNTAKKMIEISNADLDFEVSGYISLP
ELTRANRNYITILINGRYIKNFLLNRAILDGYGSKLMVGRFPIAVIDIQIDPYLADVNVHPTKQEIRISKEKELMSLISS
AIAESLREQDLIPDALENLAKSSTRGLPKPQQTSLPLKQTNFYYDKERHDFFVKSDTVEEEPVQLFNEVDKGVNPVDKQS
SVRYAQRSAADQEYDEHDSLDFKNKTKINRMIESLDKEEISTFPELEYFGQMHGTYLFAQGNGGLYIIDQHAAQERIKYE
YYRDKIGEVDDSLQQLLMPYLFEFSGADFIKLQEKMELLKQVGINLEPYGNNTFILREHPIWMKEGEIETAVYEMCDMLL
LTNEVSVKKYCAELAIMMSCKRSIKANHTLDDYSARQLIVQLSQCKNPYNCPHGRPVLVNFTKSDMEKMFRRIQENHTSL
RELGKY

Nucleotide


Download         Length: 1941 bp        

>NTDB_id=50089 KE3_RS09500 WP_020917598.1 1890989..1892929(-) (hexB) [Streptococcus lutetiensis 033]
ATGAGTAAAATTATTGAGTTGCCAGAGGTTTTGGCCAACCAGATTGCTGCAGGTGAAGTTGTTGAACGACCAGCTAGTGT
GGTTAAAGAATTGGTTGAAAATTCGATTGATGCTGGAAGTAGTCAGATTACCATCGAGATTGAAGAATCAGGTCTTAAGA
AGATTCAAGTCACTGATAATGGTGAGGGAATTTCTCAAGAGGATGTAGCGTTGAGTTTGCATCGTCATGCTACAAGTAAG
ATTAAAAGCCAAGCAGACCTTTTTCGTATCAGAACTTTGGGATTTCGCGGTGAGGCCATCCCTTCCATTGCCTCAATTAG
CCATTTCACAGTGAAAACAGCGACTGCTGATGAACACTACGGAATGCTTTTAGTGGCAAAAGGGGGCGAGATTGAGCGAC
AAGAACCAATTTCAACGCCTGTCGGGACAAAAATTACCGTTGAAAATCTTTTTTACAACACTCCTGCTCGTCTTAAGTAC
ATGAAAAGCTTGCAATCAGAGTTGGCTCATATCGTTGATGTGGTTAATCGCTTGAGCCTAGCTCATCCAGAAATTGCCTT
TACTTTGATTAATGATGGTCATCAAATGACAACGACTTCTGGGACAGGTGATTTGCGTCAAGCCATTGCTGGTATTTACG
GTTTAAATACAGCTAAGAAAATGATTGAAATCTCAAATGCCGACCTTGATTTTGAAGTGTCAGGTTATATTAGCTTACCA
GAATTGACGCGTGCCAATCGCAATTACATTACTATTTTAATCAATGGTCGCTACATCAAAAATTTCTTGCTCAACCGTGC
GATTTTGGATGGTTACGGGTCAAAATTGATGGTTGGTCGCTTCCCAATTGCTGTCATCGATATTCAAATCGATCCTTACC
TTGCTGATGTTAATGTCCACCCAACCAAGCAAGAAATTCGTATCTCAAAAGAAAAAGAACTCATGAGCTTAATCAGTTCA
GCTATTGCAGAGAGTTTGCGTGAGCAAGATTTGATTCCAGATGCTCTTGAAAATCTAGCTAAGTCAAGTACACGAGGTCT
TCCAAAACCCCAGCAAACGAGTCTGCCTTTAAAACAAACCAACTTTTACTATGATAAGGAACGTCACGATTTCTTTGTGA
AATCAGATACGGTTGAAGAAGAGCCAGTGCAGTTGTTTAATGAGGTTGACAAAGGTGTCAATCCAGTTGACAAGCAATCT
TCGGTTAGGTATGCACAGCGTTCAGCGGCAGATCAAGAGTATGATGAGCATGATAGTCTTGATTTTAAAAATAAAACGAA
AATCAATCGTATGATTGAAAGTCTTGATAAGGAGGAAATCTCTACTTTCCCTGAGTTAGAGTACTTTGGGCAAATGCACG
GTACTTATCTTTTTGCACAAGGTAATGGTGGGCTTTATATCATTGACCAGCATGCGGCGCAGGAACGTATCAAGTATGAG
TATTATCGTGACAAAATTGGCGAAGTTGATGACTCATTACAACAGTTGCTGATGCCATATCTGTTTGAATTTTCTGGGGC
AGATTTCATCAAACTTCAAGAAAAAATGGAGCTTCTAAAGCAAGTTGGTATTAATTTAGAACCATACGGCAATAACACTT
TTATCCTTCGTGAGCATCCTATTTGGATGAAGGAAGGGGAGATTGAGACAGCTGTTTATGAAATGTGCGACATGTTACTG
TTGACCAATGAAGTTTCTGTCAAGAAATACTGTGCTGAGTTAGCGATTATGATGTCATGTAAACGATCAATCAAGGCTAA
CCATACCCTTGATGACTATTCAGCCCGACAACTCATCGTTCAATTATCACAATGTAAGAATCCTTATAACTGCCCACACG
GACGTCCAGTGCTTGTTAATTTCACCAAGTCAGACATGGAAAAGATGTTCCGTCGTATTCAAGAAAATCATACAAGTTTA
AGAGAGTTAGGAAAATACTAA

Domains

Predicted by InterProScan.

MutL C terminal dimerisation domain (MutL_C)

(448-590)

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-326)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0AB33APE8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

69.313

100

0.703

Multiple sequence alignment