Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   KKZ08_RS21540 Genome accession   NZ_CP075691
Coordinates   4776702..4777364 (+) Length   220 a.a.
NCBI ID   WP_223779139.1    Uniprot ID   -
Organism   Streptomyces sp. 135     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 4771702..4782364
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KKZ08_RS21515 cseB 4771783..4772496 (-) 714 WP_223776013.1 two-component system response regulator CseB -
  KKZ08_RS21520 - 4772583..4773227 (-) 645 WP_223776014.1 hypothetical protein -
  KKZ08_RS21525 - 4773215..4773763 (-) 549 WP_223776015.1 SigE family RNA polymerase sigma factor -
  KKZ08_RS21530 - 4773961..4774896 (-) 936 WP_223776016.1 A/G-specific adenine glycosylase -
  KKZ08_RS21535 - 4775038..4776693 (+) 1656 WP_223776017.1 sensor histidine kinase -
  KKZ08_RS21540 vraR 4776702..4777364 (+) 663 WP_223779139.1 response regulator transcription factor Regulator
  KKZ08_RS21545 - 4777393..4778082 (-) 690 WP_223776018.1 phosphatase PAP2 family protein -
  KKZ08_RS21550 - 4778256..4779065 (+) 810 WP_223776019.1 hypothetical protein -
  KKZ08_RS21555 disA 4779110..4780234 (-) 1125 WP_223776020.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  KKZ08_RS21560 radA/sms 4780314..4781723 (-) 1410 WP_223776021.1 DNA repair protein RadA Machinery gene

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 22780.30 Da        Isoelectric Point: 6.5000

>NTDB_id=499685 KKZ08_RS21540 WP_223779139.1 4776702..4777364(+) (vraR) [Streptomyces sp. 135]
MPIRVLLADDEAMIRAGVRAILAAGGDIEVVAEAADGREAVSLAQAHRPDVALLDIRMPRLDGLAAGEEIVRTVPGAAVA
MLTTFSEDAYVARALGGGATGFLLKSGDPHELIAGVRAVAGGAAFLSPKVARHVIDGFGARRMGRGAAARARVQTLTPRE
REVLGLVGAGLSNPEIAARLHLVEGTVKAYVSAVLERLEVKNRVQAAIVAYEAGLVPEAD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=499685 KKZ08_RS21540 WP_223779139.1 4776702..4777364(+) (vraR) [Streptomyces sp. 135]
ATGCCCATCCGGGTCCTGCTGGCCGACGACGAGGCCATGATCCGCGCGGGCGTGCGCGCCATCCTGGCCGCGGGCGGGGA
CATCGAGGTCGTCGCCGAGGCCGCCGACGGGCGCGAGGCCGTCTCCCTGGCCCAGGCCCACCGCCCCGACGTGGCGCTGC
TCGACATCCGCATGCCGCGCCTGGACGGGCTCGCCGCGGGCGAGGAGATCGTCCGTACCGTGCCGGGGGCCGCCGTCGCC
ATGCTGACGACGTTCTCCGAAGACGCGTACGTGGCACGGGCGCTGGGCGGCGGCGCCACCGGCTTCCTGCTGAAGTCCGG
CGACCCGCATGAACTCATCGCGGGCGTACGGGCGGTGGCGGGCGGCGCCGCCTTCCTCTCACCGAAGGTGGCCCGGCACG
TCATCGACGGCTTCGGCGCCCGGCGCATGGGCCGCGGCGCCGCCGCACGCGCCCGCGTCCAGACCCTCACCCCGCGCGAA
CGCGAGGTCCTCGGCCTGGTCGGCGCGGGCCTTTCCAACCCGGAGATCGCCGCCCGCCTGCACCTCGTGGAGGGCACGGT
CAAGGCGTATGTGAGCGCGGTCCTCGAACGGCTCGAAGTCAAGAACCGCGTCCAGGCGGCGATCGTCGCGTACGAGGCGG
GGCTCGTCCCGGAAGCGGACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-115)

Bacterial regulatory proteins, luxR family (GerE)

(154-210)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

37.615

99.091

0.373
  degU Bacillus subtilis subsp. subtilis str. 168

36

100

0.368