Detailed information    

insolico Bioinformatically predicted

Overview

Name   disA   Type   Machinery gene
Locus tag   KKZ08_RS21555 Genome accession   NZ_CP075691
Coordinates   4779110..4780234 (-) Length   374 a.a.
NCBI ID   WP_223776020.1    Uniprot ID   -
Organism   Streptomyces sp. 135     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 4774110..4785234
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KKZ08_RS21535 - 4775038..4776693 (+) 1656 WP_223776017.1 sensor histidine kinase -
  KKZ08_RS21540 vraR 4776702..4777364 (+) 663 WP_223779139.1 response regulator transcription factor Regulator
  KKZ08_RS21545 - 4777393..4778082 (-) 690 WP_223776018.1 phosphatase PAP2 family protein -
  KKZ08_RS21550 - 4778256..4779065 (+) 810 WP_223776019.1 hypothetical protein -
  KKZ08_RS21555 disA 4779110..4780234 (-) 1125 WP_223776020.1 DNA integrity scanning diadenylate cyclase DisA Machinery gene
  KKZ08_RS21560 radA/sms 4780314..4781723 (-) 1410 WP_223776021.1 DNA repair protein RadA Machinery gene
  KKZ08_RS21565 - 4781910..4783658 (+) 1749 Protein_4251 hypothetical protein -
  KKZ08_RS21570 - 4783662..4784453 (-) 792 WP_223779140.1 hypothetical protein -

Sequence

Protein


Download         Length: 374 a.a.        Molecular weight: 40238.08 Da        Isoelectric Point: 4.9269

>NTDB_id=499686 KKZ08_RS21555 WP_223776020.1 4779110..4780234(-) (disA) [Streptomyces sp. 135]
MAANDRAANPGKSGGGSAADVLMRASLSAVAPGTALRDGLERILRGNTGGLIVLGWDKTVESMCTGGFILDVEFTATRLR
ELCKLDGGIVLDKDITKILRAGVQLVPDPTIPTEETGTRHRTADRVSKQVGFPVVSVSQSMRLIALYVDGQRRVLEDSAA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLALQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVDEALSELDALTHAELLELSTVAKALGYTGSPEALDSAVSPRGFRLLAKVPRLPGA
IIDRLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide


Download         Length: 1125 bp        

>NTDB_id=499686 KKZ08_RS21555 WP_223776020.1 4779110..4780234(-) (disA) [Streptomyces sp. 135]
GTGGCAGCCAACGACCGGGCAGCGAACCCCGGCAAGTCCGGCGGTGGCTCGGCCGCCGATGTGCTGATGCGCGCCTCCCT
GAGCGCCGTCGCGCCCGGCACGGCCCTGCGCGACGGCCTCGAACGCATCCTGCGCGGCAACACCGGCGGCCTGATCGTCC
TCGGCTGGGACAAGACCGTCGAGTCGATGTGCACGGGTGGTTTCATCCTGGACGTCGAGTTCACGGCGACGCGTCTGCGC
GAGCTGTGCAAGCTCGACGGCGGCATCGTCCTCGACAAGGACATCACCAAGATCCTGCGCGCCGGCGTGCAGCTGGTGCC
GGACCCGACGATCCCCACCGAGGAGACCGGCACCCGCCACCGCACGGCCGACCGCGTCTCCAAGCAGGTCGGCTTCCCGG
TCGTCTCCGTCTCGCAGTCCATGCGCCTGATCGCGCTGTACGTGGACGGGCAGCGCCGCGTCCTGGAGGACTCGGCGGCG
ATCCTCTCCCGCGCCAACCAGGCCCTCGCGACCCTGGAGCGGTACAAGCTCCGTCTCGACGAGGTCGCGGGCACGCTCTC
CGCCCTGGAGATCGAGGACCTGGTGACGGTGCGGGACGTCACGGCGGTCGCCCAGCGCCTGGAGATGGTGCGCCGCATCG
CCACGGAGATCGCCGAGTACGTGGTGGAGCTCGGCACGGACGGCCGCCTTCTCGCGCTCCAGCTGGACGAGTTGATCGCG
GGCGTCGAGCCCGAGCGTGAGCTGGTCGTCAGGGACTACGTGCCCGAGCCGACCGCCAAGCGCTCCCGCACGGTCGACGA
GGCGCTGTCCGAGCTGGACGCCCTCACCCACGCGGAGCTGCTGGAACTGTCCACCGTGGCCAAGGCCTTGGGGTACACCG
GTTCACCCGAGGCCCTGGACTCCGCCGTCTCGCCGCGCGGCTTCCGACTGCTCGCCAAGGTTCCCCGGCTTCCCGGCGCC
ATCATCGACCGCCTCGTCGAGCACTTCGGCGGCCTCCAGAAGCTGCTGGCCGCCAGCGTGGACGACCTCCAGACCGTGGA
CGGCGTGGGCGAGGCCCGTGCCCGCAGCGTCCGCGAGGGCCTCTCGCGCCTCGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTAG

Domains

Predicted by InterProScan.

DisA bacterial checkpoint controller linker region (DisA-linker)

(155-297)

DisA bacterial checkpoint controller nucleotide-binding (DAC)

(38-151)

Helix-hairpin-helix motif (HHH_2)

(324-359)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  disA Bacillus subtilis subsp. subtilis str. 168

45.429

96.524

0.438