Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   ISP08_RS04725 Genome accession   NZ_CP064056
Coordinates   993655..994284 (+) Length   209 a.a.
NCBI ID   WP_048793242.1    Uniprot ID   A0A7T1B1K5
Organism   Staphylococcus lloydii strain 23_2_7_LY     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 988655..999284
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  ISP08_RS04695 (ISP08_04695) - 988731..989447 (+) 717 WP_195719463.1 glutamine amidotransferase -
  ISP08_RS04700 (ISP08_04700) - 989517..990503 (-) 987 WP_195719462.1 aromatic acid exporter family protein -
  ISP08_RS04705 (ISP08_04705) map 990662..991414 (+) 753 WP_195719461.1 type I methionyl aminopeptidase -
  ISP08_RS04710 (ISP08_04710) - 991521..991907 (+) 387 WP_048793245.1 hypothetical protein -
  ISP08_RS04715 (ISP08_04715) liaF 991924..992625 (+) 702 WP_048793244.1 cell wall-active antibiotics response protein LiaF -
  ISP08_RS04720 (ISP08_04720) vraS 992622..993665 (+) 1044 WP_061855636.1 sensor histidine kinase Regulator
  ISP08_RS04725 (ISP08_04725) vraR 993655..994284 (+) 630 WP_048793242.1 response regulator transcription factor Regulator
  ISP08_RS04730 (ISP08_04730) - 994358..995446 (-) 1089 WP_195719460.1 YihY/virulence factor BrkB family protein -
  ISP08_RS04735 (ISP08_04735) - 995701..995982 (-) 282 WP_048793240.1 hypothetical protein -
  ISP08_RS04740 (ISP08_04740) - 995989..996453 (-) 465 WP_048793239.1 low molecular weight protein-tyrosine-phosphatase -
  ISP08_RS04745 (ISP08_04745) - 996586..996789 (+) 204 WP_048793238.1 DUF1128 family protein -
  ISP08_RS04750 (ISP08_04750) - 996802..998040 (+) 1239 WP_195719459.1 aminopeptidase -
  ISP08_RS04755 (ISP08_04755) - 998065..998592 (+) 528 WP_195719512.1 acyl-CoA thioesterase -

Sequence

Protein


Download         Length: 209 a.a.        Molecular weight: 23665.27 Da        Isoelectric Point: 4.7892

>NTDB_id=498836 ISP08_RS04725 WP_048793242.1 993655..994284(+) (vraR) [Staphylococcus lloydii strain 23_2_7_LY]
MPIKVLFVDDHEMVRIGISSYLSTQPDIEVVGEGKSGKEAIELAHELKPDLILMDLLMDDMDGVDATAQVKKDLPHIKVV
MLTSYIEDNEVYRALDSGVDSYILKTTSAKDIAEAIRKTQNDESVFEAEVLVKMRNRMKQRAELYEMLTEREMEILLLIA
KGYSNQEIASASHITIKTVKTHVSNILSKLEVQDRTQAVIYAFQHNLIQ

Nucleotide


Download         Length: 630 bp        

>NTDB_id=498836 ISP08_RS04725 WP_048793242.1 993655..994284(+) (vraR) [Staphylococcus lloydii strain 23_2_7_LY]
ATGCCAATTAAAGTTTTATTTGTTGATGATCATGAAATGGTACGTATTGGGATATCAAGTTATTTATCAACACAACCAGA
TATTGAAGTAGTAGGAGAAGGAAAGTCAGGTAAAGAAGCGATTGAATTAGCGCATGAATTAAAACCCGATTTAATTTTAA
TGGACTTATTGATGGATGATATGGATGGGGTAGACGCTACTGCTCAAGTAAAAAAAGATTTACCACATATCAAAGTTGTA
ATGTTAACAAGTTACATTGAGGATAATGAAGTGTATCGTGCTTTAGACTCTGGTGTTGATAGTTATATCTTAAAAACAAC
GAGTGCAAAAGACATTGCAGAAGCAATACGTAAAACACAAAATGATGAATCTGTTTTTGAAGCAGAAGTTTTAGTGAAAA
TGCGAAATCGTATGAAACAACGTGCAGAATTATATGAGATGTTAACTGAAAGAGAAATGGAAATTTTATTACTCATTGCT
AAAGGCTATTCTAACCAAGAAATTGCTAGCGCCTCTCACATTACCATCAAGACAGTAAAAACGCATGTTAGTAATATATT
AAGTAAATTAGAAGTTCAAGATAGAACACAAGCTGTTATATACGCTTTCCAACATAATTTAATTCAATAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-117)

Bacterial regulatory proteins, luxR family (GerE)

(147-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7T1B1K5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

89.952

100

0.9
  degU Bacillus subtilis subsp. subtilis str. 168

34.375

100

0.368