Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SSUD12_RS02170 Genome accession   NC_017621
Coordinates   425035..426327 (+) Length   430 a.a.
NCBI ID   WP_014637534.1    Uniprot ID   -
Organism   Streptococcus suis D12     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 420035..431327
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SSUD12_RS02145 (SSUD12_0408) - 420840..421481 (+) 642 WP_002937025.1 response regulator transcription factor -
  SSUD12_RS02150 (SSUD12_0409) - 421531..422931 (+) 1401 WP_014637530.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  SSUD12_RS02155 (SSUD12_0410) - 422933..423304 (+) 372 WP_014637531.1 S1 RNA-binding domain-containing protein -
  SSUD12_RS02160 (SSUD12_0411) cysK 423330..424256 (-) 927 WP_014637532.1 cysteine synthase A -
  SSUD12_RS02165 (SSUD12_0412) - 424346..424978 (-) 633 WP_014637533.1 YigZ family protein -
  SSUD12_RS02170 (SSUD12_0413) comFA/cflA 425035..426327 (+) 1293 WP_014637534.1 DEAD/DEAH box helicase Machinery gene
  SSUD12_RS02175 (SSUD12_0414) - 426320..426985 (+) 666 WP_014637535.1 ComF family protein -
  SSUD12_RS02180 (SSUD12_0415) hpf 427062..427604 (+) 543 WP_014637536.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  SSUD12_RS02185 (SSUD12_0416) - 427666..428055 (+) 390 WP_014637537.1 hypothetical protein -

Sequence

Protein


Download         Length: 430 a.a.        Molecular weight: 48987.50 Da        Isoelectric Point: 9.0337

>NTDB_id=49776 SSUD12_RS02170 WP_014637534.1 425035..426327(+) (comFA/cflA) [Streptococcus suis D12]
MKELENYYGRLFTKYQLTAKEREIAEKVPSITKKNNCFRCGTTFEEENKLPNDAYYCRACLLLGRVRSDEKLYHFPQKDF
PITKCLKWKGQLTDWQQRISDGLVANVENNRATLVHAVTGAGKTEMIYHTVASVIDKGGAVCLASPRIDVCIELYKRLQN
DFSVPISLLHGESEPYFRTPLVVATTHQLLKFYQAFDLVLIDEVDAFPYADNPMLYRAADNAVKEAGVQVFLTATSTDEL
DKKVRTGKLSRLSLPRRFHGNPLVVPQKVWFSRFDDTLKKNRLVPKLKKAIEEQRKSGFPLLIFVPEISKGQEFTKIMKK
TFPEETIGFVSSQTENRLEIVEGFRKREITVLISTTILERGVTFPCVDVFVVQANHYLYTASSLVQIAGRVGRSMERPTG
LLQFYHEGSTGDIEKAIAEIKQMNKEAGYV

Nucleotide


Download         Length: 1293 bp        

>NTDB_id=49776 SSUD12_RS02170 WP_014637534.1 425035..426327(+) (comFA/cflA) [Streptococcus suis D12]
ATGAAAGAATTAGAAAATTATTATGGAAGATTATTTACCAAATACCAATTGACAGCAAAAGAAAGAGAAATAGCAGAAAA
AGTGCCAAGTATTACAAAAAAGAATAACTGCTTTCGCTGTGGAACAACTTTTGAAGAAGAAAACAAATTGCCAAACGATG
CTTATTACTGTCGAGCCTGCTTGCTTCTAGGCAGAGTGCGGTCGGACGAAAAACTCTATCATTTTCCTCAGAAAGATTTT
CCAATCACTAAGTGTTTAAAGTGGAAAGGTCAACTAACTGATTGGCAACAAAGAATTTCAGATGGACTAGTTGCAAACGT
GGAAAATAATCGTGCAACATTGGTTCATGCAGTAACAGGAGCAGGTAAGACAGAAATGATTTACCACACCGTTGCCTCAG
TGATTGATAAAGGCGGAGCGGTTTGCTTAGCCAGTCCTCGAATTGATGTTTGTATCGAACTCTATAAACGTCTGCAAAAT
GATTTTTCAGTTCCAATTAGTTTACTACATGGAGAGTCTGAACCCTATTTCCGAACTCCATTAGTTGTAGCAACCACACA
TCAGTTATTAAAATTTTATCAGGCCTTTGATTTGGTTTTGATTGATGAAGTAGACGCCTTTCCCTATGCAGATAATCCCA
TGCTCTATCGAGCAGCAGACAATGCGGTCAAGGAAGCCGGTGTTCAAGTTTTTCTGACGGCGACTTCAACAGATGAATTG
GATAAAAAAGTCAGAACGGGCAAATTAAGCCGTCTTAGTTTACCAAGGCGATTTCATGGCAATCCGCTTGTTGTCCCGCA
AAAAGTCTGGTTTAGTAGATTCGATGATACCCTAAAGAAAAATAGACTAGTCCCAAAGTTGAAAAAAGCGATTGAAGAAC
AGAGAAAGTCGGGCTTTCCCTTACTCATTTTTGTCCCAGAAATCTCCAAAGGTCAAGAATTTACCAAGATAATGAAAAAA
ACATTCCCAGAAGAAACAATTGGCTTTGTATCCAGTCAAACAGAAAATCGCCTTGAAATCGTTGAGGGGTTTCGCAAGAG
AGAAATCACAGTCTTAATCTCGACTACTATTCTTGAACGTGGGGTAACCTTCCCATGTGTAGACGTCTTTGTTGTTCAAG
CCAATCATTACCTCTACACAGCGTCAAGTCTTGTTCAGATTGCGGGCCGGGTCGGCAGGAGTATGGAACGTCCGACTGGG
TTACTCCAGTTTTATCATGAAGGAAGTACAGGAGACATTGAAAAGGCAATCGCTGAAATTAAACAGATGAACAAGGAGGC
TGGATATGTCTAA

Domains

Predicted by InterproScan.

Type III restriction enzyme, res subunit (ResIII)

(91-235)

Helicase conserved C-terminal domain (Helicase_C)

(289-393)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus mitis NCTC 12261

67.285

100

0.674
  comFA/cflA Streptococcus pneumoniae Rx1

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae D39

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae R6

66.589

100

0.667
  comFA/cflA Streptococcus pneumoniae TIGR4

66.589

100

0.667
  comFA/cflA Streptococcus mitis SK321

66.125

100

0.663
  comFA Lactococcus lactis subsp. cremoris KW2

53.904

92.326

0.498
  comFA Latilactobacillus sakei subsp. sakei 23K

37.819

100

0.379
  comFA Bacillus subtilis subsp. subtilis str. 168

37.59

96.512

0.363

Multiple sequence alignment